EMC3_YEAST - dbPTM
EMC3_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID EMC3_YEAST
UniProt AC P36039
Protein Name ER membrane protein complex subunit 3
Gene Name EMC3
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 253
Subcellular Localization Endoplasmic reticulum membrane
Multi-pass membrane protein .
Protein Description The EMC seems to be required for efficient folding of proteins in the endoplasmic reticulum (ER)..
Protein Sequence MLLDDQLKYWVLLPISIVMVLTGVLKQYIMTLITGSSANEAQPRVKLTEWQYLQWAQLLIGNGGNLSSDAFAAKKEFLVKDLTEERHLAKAKQQDGSQAGEVPNPFNDPSMSNAMMNMAKGNMASFIPQTIIMWWVNHFFAGFILMQLPFPLTAKFKEMLQTGIICQDLDVRWVSSISWYFISVLGLNPVYNLIGLNDQDMGIQAGIGGPQGPQGPPQSQVDKAMHAMANDLTIIQHETCLDNVEQRVLKQYM
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
80AcetylationAKKEFLVKDLTEERH
HCHHHHHCCCHHHHH
49.5224489116

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of EMC3_YEAST !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of EMC3_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of EMC3_YEAST !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
SEY1_YEASTSEY1physical
19325107
EMC1_YEASTEMC1physical
19325107
SOP4_YEASTSOP4physical
19325107
EMC2_YEASTEMC2physical
19325107
YD056_YEASTYDR056Cphysical
19325107
VDAC1_YEASTPOR1physical
19325107
GTO2_YEASTECM4physical
19325107
ECM5_YEASTECM5physical
19325107
GSF2_YEASTGSF2physical
19325107
CUE1_YEASTCUE1genetic
19325107
HLJ1_YEASTHLJ1genetic
19325107
RPN4_YEASTRPN4genetic
19325107
UBC7_YEASTUBC7genetic
19325107
UBX4_YEASTUBX4genetic
19325107
SSH1_YEASTSSH1genetic
19325107
GPR1_YEASTGPR1genetic
27708008
ASK10_YEASTASK10genetic
27708008
RAD1_YEASTRAD1genetic
27708008
TRS20_YEASTTRS20genetic
27708008
UAP1_YEASTQRI1genetic
27708008
RIFK_YEASTFMN1genetic
27708008
MOB2_YEASTMOB2genetic
27708008
XPO1_YEASTCRM1genetic
27708008
CP51_YEASTERG11genetic
27708008
BRL1_YEASTBRL1genetic
27708008
ARP4_YEASTARP4genetic
27708008
MED14_YEASTRGR1genetic
27708008
NEP1_YEASTEMG1genetic
27708008
CAP_YEASTSRV2genetic
27708008
SEC62_YEASTSEC62genetic
27708008
TBF1_YEASTTBF1genetic
27708008
NIP7_YEASTNIP7genetic
27708008
SSH1_YEASTSSH1genetic
27708008
PP2C1_YEASTPTC1genetic
27708008
RPN4_YEASTRPN4genetic
27708008
BRE1_YEASTBRE1genetic
27708008
GET3_YEASTGET3genetic
27708008
RAD55_YEASTRAD55genetic
27708008
OMS1_YEASTOMS1genetic
27708008
STP1_YEASTSTP1genetic
27708008
GET2_YEASTGET2genetic
27708008
GUP1_YEASTGUP1genetic
27708008
CUE3_YEASTCUE3genetic
27708008
CHO2_YEASTCHO2genetic
27708008
SMI1_YEASTSMI1genetic
27708008
AP3B_YEASTAPL6genetic
27708008
TBP7_YEASTYTA7genetic
27708008
YOR1_YEASTYOR1genetic
27708008
SLT2_YEASTSLT2genetic
27708008
SSF1_YEASTSSF1genetic
27708008
SSP1_YEASTSSP1genetic
27708008
SDHX_YEASTYJL045Wgenetic
27708008
ICT1_YEASTICT1genetic
27708008
NKP2_YEASTNKP2genetic
27708008
MID2_YEASTMID2genetic
27708008
AIM34_YEASTAIM34genetic
27708008
PHO80_YEASTPHO80genetic
27708008
CG12_YEASTCLN2genetic
27708008
YME1_YEASTYME1genetic
27708008
ASR1_YEASTASR1genetic
27708008
KPC1_YEASTPKC1genetic
29674565
GET2_YEASTGET2genetic
29674565
CHO2_YEASTCHO2genetic
29674565
EDE1_YEASTEDE1genetic
29674565
TFB1_YEASTTFB1genetic
29674565
PUF4_YEASTPUF4genetic
29674565
GET1_YEASTGET1genetic
29674565
BRL1_YEASTBRL1genetic
29674565
ATC7_YEASTNEO1genetic
29674565
POB3_YEASTPOB3genetic
29674565
MAS5_YEASTYDJ1genetic
29674565
PHO80_YEASTPHO80genetic
29674565
TRS20_YEASTTRS20genetic
29674565
THRC_YEASTTHR4genetic
29674565
INO2_YEASTINO2genetic
29674565
SLT2_YEASTSLT2genetic
29674565
DCP2_YEASTDCP2genetic
29674565
NAB3_YEASTNAB3genetic
29674565

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of EMC3_YEAST

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Related Literatures of Post-Translational Modification

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