ASR1_YEAST - dbPTM
ASR1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID ASR1_YEAST
UniProt AC Q06834
Protein Name Alcohol-sensitive RING finger protein 1
Gene Name ASR1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 288
Subcellular Localization Cytoplasm . Nucleus . Predominantly cytoplasmic. Accumulates in the nucleus specifically upon alcohol stress. Shuttles between the nucleus and the cytoplasm in a XPO1-dependent manner.
Protein Description Required for tolerance to alcohol..
Protein Sequence MEECPICLADDQEGEQFGCLNVCGHKFHLNCIREWHKYSINLKCPICRVESTHLEVGEGQHALSINLKMGFMIKNAIDYVGAETTNERNEDDTGEQDQEIEFLSERLRGTLVMDTIKIIQCSICGDTDVSRLSLYCQDCEAIYHETCLRGLACEVGDRNTWQECTDCRSNALLELRMGAISSQLASYDSRNSMIFAGELRDKHSVKTQQMYEQIRNAKHKIQMHVRRALDRYPLPLLRFKDAYKHVNKQVSRKLYRLSDNKYLPDQYDYDSLARTGVHTELLIYCHDE
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
117UbiquitinationTLVMDTIKIIQCSIC
EEECCCEEEEEEEEC
35.5323749301
192PhosphorylationASYDSRNSMIFAGEL
CCCCCCCCEEEEHHC
16.4926447709
204PhosphorylationGELRDKHSVKTQQMY
HHCCCCCCCCHHHHH
30.9228889911
261UbiquitinationLYRLSDNKYLPDQYD
HHHHCCCCCCCCCCC
53.8323749301

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of ASR1_YEAST !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of ASR1_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of ASR1_YEAST !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
RPB11_YEASTRPB11physical
11805837
RPB3_YEASTRPB3physical
11805837
YD131_YEASTYDR131Cphysical
11805837
RPB9_YEASTRPB9physical
11805837
FKBP_YEASTFPR1physical
11805837
RPB1_YEASTRPO21physical
11805837
RPB1_YEASTRPO21physical
16554755
RV167_YEASTRVS167physical
16554755
ARPC5_YEASTARC15physical
16554755
CORO_YEASTCRN1physical
16554755
CAPZA_YEASTCAP1physical
16554755
HSC82_YEASTHSC82physical
16554755
RPB2_YEASTRPB2physical
16429126
RPB3_YEASTRPB3physical
16429126
RPB1_YEASTRPO21physical
16429126
ENO2_YEASTENO2physical
16429126
ALF_YEASTFBA1physical
16429126
PGK_YEASTPGK1physical
16429126
IMB5_YEASTKAP114physical
17485461
IMB1_YEASTKAP95physical
17485461
IMB4_YEASTKAP123physical
17485461
IMB3_YEASTPSE1physical
17485461
IMB2_YEASTKAP104physical
17485461
HSP7F_YEASTSSE1physical
19536198
SSB1_YEASTSSB1physical
19536198
RPB1_YEASTRPO21physical
19064926
RPB2_YEASTRPB2physical
19064926
RPB3_YEASTRPB3physical
19064926
RPAB1_YEASTRPB5physical
19064926
RPAB2_YEASTRPO26physical
19064926
RPAB3_YEASTRPB8physical
19064926
RPB9_YEASTRPB9physical
19064926
RPB11_YEASTRPB11physical
19064926
RPAB5_YEASTRPB10physical
19064926
RPAB4_YEASTRPC10physical
19064926
RPB4_YEASTRPB4physical
19064926
CALM_YEASTCMD1physical
21726536
UB2D1_HUMANUBE2D1physical
19064926
RPAB4_YEASTRPC10physical
23418395
RPB9_YEASTRPB9physical
23418395
RPB11_YEASTRPB11physical
23418395
RPAB5_YEASTRPB10physical
23418395
RPAB2_YEASTRPO26physical
23418395
RPB1_YEASTRPO21physical
23418395
RPB3_YEASTRPB3physical
23418395
RPAB1_YEASTRPB5physical
23418395
RPB2_YEASTRPB2physical
23418395
RPAB3_YEASTRPB8physical
23418395
T2FA_YEASTTFG1physical
23418395
T2FB_YEASTTFG2physical
23418395
SPT5_YEASTSPT5physical
23418395
RTR1_YEASTRTR1physical
23418395
GPN1_YEASTNPA3physical
23418395
SET2_YEASTSET2physical
23418395
RPB4_YEASTRPB4physical
23418395
RPB7_YEASTRPB7physical
23418395
SWE1_YEASTSWE1genetic
25646695
CORO_YEASTCRN1genetic
25646695
ATG15_YEASTATG15genetic
27708008
VPS41_YEASTVPS41genetic
27708008
SGF73_YEASTSGF73genetic
27708008
VAM7_YEASTVAM7genetic
27708008
SAC1_YEASTSAC1genetic
27708008
RS3A2_YEASTRPS1Bgenetic
27708008
REI1_YEASTREI1genetic
27708008
YCQ6_YEASTYCR016Wgenetic
27708008
SLX5_YEASTSLX5genetic
27708008
RS29B_YEASTRPS29Bgenetic
27708008
APA2_YEASTAPA2genetic
27708008
AIM11_YEASTAIM11genetic
27708008
ATC1_YEASTPMR1genetic
27708008
HUR1_YEASTHUR1genetic
27708008
XRN1_YEASTXRN1genetic
27708008
PHB2_YEASTPHB2genetic
27708008
SLH1_YEASTSLH1genetic
27708008
HOS4_YEASTHOS4genetic
27708008
BFA1_YEASTBFA1genetic
27708008
CBF1_YEASTCBF1genetic
27708008
DCW1_YEASTDCW1genetic
27708008
ELM1_YEASTELM1genetic
27708008
CYT2_YEASTCYT2genetic
27708008
CTK1_YEASTCTK1genetic
27708008
MIC60_YEASTMIC60genetic
27708008
TRK2_YEASTTRK2genetic
27708008
CORO_YEASTCRN1genetic
27708008
TSA1_YEASTTSA1genetic
27708008
RCF2_YEASTRCF2genetic
27708008
AIM41_YEASTAIM41genetic
27708008
YO223_YEASTDSC3genetic
27708008
DGK1_YEASTDGK1genetic
27708008
HAP5_YEASTHAP5genetic
27708008
UBP3_YEASTUBP3physical
26787877
BRE5_YEASTBRE5physical
26787877
RPB1_YEASTRPO21physical
26787877
RPB2_YEASTRPB2physical
26787877
RPB3_YEASTRPB3physical
26787877
RPB4_YEASTRPB4physical
26787877
RPAB1_YEASTRPB5physical
26787877
RPAB2_YEASTRPO26physical
26787877
RPB7_YEASTRPB7physical
26787877
RPAB3_YEASTRPB8physical
26787877
RPB9_YEASTRPB9physical
26787877
RPAB5_YEASTRPB10physical
26787877
RPB11_YEASTRPB11physical
26787877
RPAB4_YEASTRPC10physical
26787877

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of ASR1_YEAST

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Related Literatures of Post-Translational Modification

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