CGS6_YEAST - dbPTM
CGS6_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID CGS6_YEAST
UniProt AC P32943
Protein Name S-phase entry cyclin-6
Gene Name CLB6
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 380
Subcellular Localization
Protein Description Involved in G1/S and or S phase progression. Interacts with CDC28..
Protein Sequence MNCIPSPISERKIQINNEDCIGKENAFHTIPRESSINLTPHSTNEKKVLSEVNSNKIDSLQLPRGKLQRDSTHLEKTRKRQLSNDSTDPIEPKTVKKIKCHQWKNLDSIEMDDPFMVAEYTDSIFSHLYEKEIQMLPTHNYLMDTQSPYHLKSSMRALLIDWLVEVHEKFHCLPETLFLAINLLDRFLSQNVVKLNKLQLLCITCLFIACKFEEVKLPKITNFAYVTDGAATVEGIRKAELFVLSSLGYNISLPNPLNFIRRISKADNYCIETRNMAKFIMEYSICCNKFIHLKPSYLAAMSMYIARKIKNENSKWDETFIHYSGGIDIESDPAFKDFISELVEDIAVPDTNLDSLRLKYKKPKHGMVYFKVFDWCKQKR
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
296PhosphorylationKFIHLKPSYLAAMSM
CCHHCCHHHHHHHHH
31.0628889911
297PhosphorylationFIHLKPSYLAAMSMY
CHHCCHHHHHHHHHH
14.6428889911
302PhosphorylationPSYLAAMSMYIARKI
HHHHHHHHHHHHHHH
12.0528889911

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources
-KUbiquitinationE3 ubiquitin ligaseCDC4P07834
PMID:22199232

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of CGS6_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of CGS6_YEAST !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
CGS5_YEASTCLB5genetic
9763426
CDK1_YEASTCDC28genetic
9763426
YPK1_YEASTYPK1genetic
19269370
MRC1_YEASTMRC1genetic
19269370
TWF1_YEASTTWF1genetic
19269370
PPME1_YEASTPPE1genetic
19269370
MSG5_YEASTMSG5genetic
19269370
CGS5_YEASTCLB5genetic
19269370
CDK1_YEASTCDC28physical
20489023
CKS1_YEASTCKS1physical
20489023
FAR1_YEASTFAR1physical
20489023
PSH1_YEASTPSH1physical
20489023
RAD17_YEASTRAD17physical
20489023
SIC1_YEASTSIC1physical
20489023
CDC7_YEASTCDC7genetic
18321994
DBF4_YEASTDBF4genetic
18321994
SECU_YEASTPDS1genetic
21518961
UPC2_YEASTUPC2genetic
21127252
SIC1_YEASTSIC1physical
21963604
CG22_YEASTCLB2genetic
23468650
SCC1_YEASTMCD1genetic
23468650
IMG2_YEASTIMG2genetic
27708008
GPR1_YEASTGPR1genetic
27708008
RM01_YEASTMRPL1genetic
27708008
MED20_YEASTSRB2genetic
27708008
LRP1_YEASTLRP1genetic
27708008
COXM1_YEASTCMC1genetic
27708008
RL22A_YEASTRPL22Agenetic
27708008
SST2_YEASTSST2genetic
27708008
MAC1_YEASTMAC1genetic
27708008
SIN3_YEASTSIN3genetic
27708008
TOP1_YEASTTOP1genetic
27708008
INO4_YEASTINO4genetic
27708008
NCBP2_YEASTCBC2genetic
27708008
NEW1_YEASTNEW1genetic
27708008
CGS5_YEASTCLB5genetic
27708008

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of CGS6_YEAST

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Related Literatures of Post-Translational Modification

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