YL455_YEAST - dbPTM
YL455_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID YL455_YEAST
UniProt AC Q06188
Protein Name PWWP domain-containing protein YLR455W
Gene Name YLR455W
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 304
Subcellular Localization Nucleus .
Protein Description
Protein Sequence MTKDIRTGDLVLCKVGSFPPWPAVVFPQRLLRNDVYRKRKSNCVAVCFFNDPTYYWEQPSRLKELDQDSIHNFILEHSKNANQRELVNAYKEAKNFDDFNVFLQEKFEEENRLSDLKAFEKSEGSKIVAGEDPFVGRTKVVNKRKKNSISIKEDPEDNQKSNEEESKPNIKPSKKKRPTANSGGKSNSGNKKKVKLDYSRRVEISQLFRRRIQRNLIQRETPPTEHEIKETHELLNRIYENSDTKRPFFDLKALRESKLHKLLKAIVNDPDLGEFHPLCKEILLSWADLITELKKEKLQALPTP
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
69PhosphorylationLKELDQDSIHNFILE
HHHCCHHHHHHHHHH
21.8021440633
94UbiquitinationVNAYKEAKNFDDFNV
HHHHHHHHCCCCCHH
60.2724961812
114PhosphorylationFEEENRLSDLKAFEK
HHHHCCHHHHHHHHH
37.3530377154
146UbiquitinationKVVNKRKKNSISIKE
ECCCCCCCCCCCCCC
61.0224961812
148PhosphorylationVNKRKKNSISIKEDP
CCCCCCCCCCCCCCC
26.9620377248
150PhosphorylationKRKKNSISIKEDPED
CCCCCCCCCCCCCCC
27.6821440633
152UbiquitinationKKNSISIKEDPEDNQ
CCCCCCCCCCCCCCC
49.6424961812
152AcetylationKKNSISIKEDPEDNQ
CCCCCCCCCCCCCCC
49.6425381059
160UbiquitinationEDPEDNQKSNEEESK
CCCCCCCCCCCHHCC
62.6024961812
161PhosphorylationDPEDNQKSNEEESKP
CCCCCCCCCCHHCCC
39.4421551504
166PhosphorylationQKSNEEESKPNIKPS
CCCCCHHCCCCCCCC
57.6129136822
252AcetylationKRPFFDLKALRESKL
CCCCCCHHHHHHHHH
47.4124489116
303PhosphorylationEKLQALPTP------
HHHHCCCCC------
42.3422369663

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of YL455_YEAST !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of YL455_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of YL455_YEAST !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
H2B2_YEASTHTB2physical
16554755
FBRL_YEASTNOP1physical
16554755
HMO1_YEASTHMO1physical
16554755
YRA1_YEASTYRA1physical
16554755
EBP2_YEASTEBP2physical
16554755
STM1_YEASTSTM1physical
16554755
PWP1_YEASTPWP1physical
16554755
NOP56_YEASTNOP56physical
16554755
RRP5_YEASTRRP5physical
16554755
HAS1_YEASTHAS1physical
16554755
TOP2_YEASTTOP2physical
16554755
RPA49_YEASTRPA49physical
16554755
BRX1_YEASTBRX1physical
16554755
NOC2_YEASTNOC2physical
16554755
RRS1_YEASTRRS1physical
16554755
NOP58_YEASTNOP58physical
16554755
ATM_YEASTTEL1genetic
17314980
RPB3_YEASTRPB3genetic
17314980
MDM35_YEASTMDM35genetic
17314980
YBI6_YEASTYBL086Cgenetic
17314980
IFH1_YEASTIFH1physical
18719252
H2B2_YEASTHTB2physical
25104842
H4_YEASTHHF1physical
25104842
H2A2_YEASTHTA2physical
25104842
YNG1_YEASTYNG1physical
25104842
NTO1_YEASTNTO1physical
25104842
SAS3_YEASTSAS3physical
25104842
TAF14_YEASTTAF14physical
25104842
H3_YEASTHHT1physical
25104842
RPB4_YEASTRPB4physical
25104842
EAF6_YEASTEAF6physical
25104842
RPB2_YEASTRPB2physical
25104842
SYIC_YEASTILS1genetic
27708008
APC11_YEASTAPC11genetic
27708008
TECR_YEASTTSC13genetic
27708008
PRP9_YEASTPRP9genetic
27708008
UBC3_YEASTCDC34genetic
27708008
RRP1_YEASTRRP1genetic
27708008
RPB7_YEASTRPB7genetic
27708008
RSP5_YEASTRSP5genetic
27708008
MOB2_YEASTMOB2genetic
27708008
PRP18_YEASTPRP18genetic
27708008
ARP4_YEASTARP4genetic
27708008
SEC22_YEASTSEC22genetic
27708008
TAD3_YEASTTAD3genetic
27708008
RPC6_YEASTRPC34genetic
27708008
TYSY_YEASTCDC21genetic
27708008
RPB2_YEASTRPB2genetic
27708008
APC5_YEASTAPC5genetic
27708008
CLP1_YEASTCLP1genetic
27708008

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of YL455_YEAST

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Related Literatures of Post-Translational Modification

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