RT09_YEAST - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RT09_YEAST
• UniProt AC: P38120
• Protein Name: 37S ribosomal protein S9, mitochondrial
• Gene Name: MRPS9
• Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
• Sequence Length: 278
• Subcellular Localization: Mitochondrion . Mitoribosomes are tethered to the mitochondrial inner membrane and spatially aligned with the membrane insertion machinery through two distinct membrane contact sites, formed by the 21S rRNA expansion segment 96-ES1 and the inner memb
• Protein Description: Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane..
• Protein Sequence: MFSRLSLFRRAALAPAPMRMSFRTIYQKTEDELPRRIVPKLATFYSANPNHEDRINRLERLLRKYIKLPSQNNNEAQQTKAPWISFDEYALIGGGTKLKPTQYTQLLYMLNKLHNIDPQLTNDEITSELSQYYKKSSMLSNNIKIKTLDEFGRSIAVGKRKSSTAKVFVVRGTGEILVNGRQLNDYFLKMKDRESIMYPLQVIESVGKYNIFATTSGGGPTGQAESIMHAIAKALVVFNPLLKSRLHKAGVLTRDYRHVERKKPGKKKARKMPTWVKR

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
43	Phosphorylation	RIVPKLATFYSANPN CHHHHHHHHHHCCCC	33.28	22369663
45	Phosphorylation	VPKLATFYSANPNHE HHHHHHHHHCCCCHH	11.52	22369663
46	Phosphorylation	PKLATFYSANPNHED HHHHHHHHCCCCHHH	19.85	22369663
85	Phosphorylation	QTKAPWISFDEYALI HCCCCCEECCCEEEC	23.83	22369663
89	Phosphorylation	PWISFDEYALIGGGT CCEECCCEEECCCCC	14.46	22369663
96	Phosphorylation	YALIGGGTKLKPTQY EEECCCCCCCCCCHH	36.16	22369663
136	Phosphorylation	LSQYYKKSSMLSNNI HHHHHHHHHHHCCCC	19.48	19823750
137	Phosphorylation	SQYYKKSSMLSNNIK HHHHHHHHHHCCCCE	32.40	19823750
140	Phosphorylation	YKKSSMLSNNIKIKT HHHHHHHCCCCEEEE	21.13	19823750
243	Acetylation	VVFNPLLKSRLHKAG HHHCHHHHHHHHHHC	41.01	22865919

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RT09_YEAST !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RT09_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RT09_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SRS2_YEAST	SRS2	genetic	21459050
ERG3_YEAST	ERG3	genetic	27708008
RL31B_YEAST	RPL31B	genetic	27708008
RIT1_YEAST	RIT1	genetic	27708008
YO268_YEAST	YOR268C	genetic	27708008
CHL1_YEAST	CHL1	genetic	27708008
SWC4_YEAST	SWC4	genetic	27708008
SEC22_YEAST	SEC22	genetic	27708008
TEM1_YEAST	TEM1	genetic	27708008
ORC1_YEAST	ORC1	genetic	27708008
POB3_YEAST	POB3	genetic	27708008
BET5_YEAST	BET5	genetic	27708008
GEM1_YEAST	GEM1	genetic	27708008
YAJ9_YEAST	YAR029W	genetic	27708008
ATG15_YEAST	ATG15	genetic	27708008
GIR2_YEAST	GIR2	genetic	27708008
YFB2_YEAST	YFL012W	genetic	27708008
AVL9_YEAST	AVL9	genetic	27708008
SWS2_YEAST	SWS2	genetic	27708008
STI1_YEAST	STI1	genetic	27708008
EXO1_YEAST	EXO1	genetic	27708008
AFI1_YEAST	AFI1	genetic	27708008
DGK1_YEAST	DGK1	genetic	27708008
YP027_YEAST	YPR027C	genetic	27708008

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.