RIT1_YEAST - dbPTM
RIT1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID RIT1_YEAST
UniProt AC P23796
Protein Name tRNA A64-2'-O-ribosylphosphate transferase
Gene Name RIT1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 513
Subcellular Localization
Protein Description tRNA backbone modifying enzyme that mediates initiator/ elongator tRNA discrimination. This enzyme modifies exclusively the initiator tRNA in position 64 using 5'-phosphoribosyl-1'-pyrophosphate as the modification donor. Recognize the stem-loop IV region that is unique in eukaryotic cytoplasmic initiator tRNAs..
Protein Sequence MVSRLSKRYRSRVQFSISVMDENIYLSLSQINKDIRKENKSVRNRLQSILLDNKFLQDRVIPIFPHYPLIPNERCGLWYCNPSSFKQTSYFKSTDGHVNQWDFSTRRLNFHLLETIRDNKGIIIVDSTRRGKKIPDALSKTVPIWCAVLNTLMLQETEKNVAIDKVLYLPPETVPKSEYDMIKRKIPELVAKLQKLNIIDSKKLNELFMGKLLRPIWVHPGSSLLDHSVDYFTGEVQEYEAWETPEDQNIIPIILCTVSYQAQDGMDKRYGFTYVQGAADDHELWSFGLDSNMFWAHIEYLGDASYSDDQLHDYIMDLAAAKLRNQCYIQDKGSLDEVFGNIDKITNEISLGKVSSGLTINKNLKQKLKSEYGKVIIFSNSVTVAEDTDDEEESGTDPFISIYKLQSGDKKSSKALRSTFPRIHGEIQSLFTNRDEKIKPMLICCNTGTDMSIGVILSILCTKYTEEWMLTSELPDISKLIVRKHLTKLISHLKGRNVNPSRATLNSVNSFLM
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
201PhosphorylationQKLNIIDSKKLNELF
HHCCCCCHHHHHHHH		22.6819795423
356PhosphorylationISLGKVSSGLTINKN
CCCCCCCCCCCCCHH		40.5927214570
388PhosphorylationSVTVAEDTDDEEESG
CEEEECCCCCCCCCC		36.5327214570
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of RIT1_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of RIT1_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of RIT1_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
EF1A_YEASTTEF2genetic
10485288
IF2G_YEASTGCD11genetic
10485288
IF2A_YEASTSUI2genetic
10485288
IF2B_YEASTSUI3genetic
10485288
UBI4P_YEASTUBI4genetic
19061648
ERF3_YEASTSUP35genetic
19061648
EI2BE_YEASTGCD6genetic
19061648
NU170_YEASTNUP170genetic
19061648
POP8_YEASTPOP8genetic
19061648
POP7_YEASTPOP7genetic
19061648
XRN1_YEASTXRN1genetic
19061648
IF4F1_YEASTTIF4631genetic
19061648
LTV1_YEASTLTV1genetic
19061648
NU120_YEASTNUP120genetic
19061648
IF2M_YEASTIFM1genetic
19061648
PFD5_YEASTGIM5genetic
19061648
ELP6_YEASTELP6genetic
19061648
ELP3_YEASTELP3genetic
19061648
ELP5_YEASTIKI1genetic
19061648
IF2G_YEASTGCD11genetic
19061648
RLI1_YEASTRLI1genetic
19061648
NOP15_YEASTNOP15genetic
19061648
ELP3_YEASTELP3genetic
19547744
RIM1_YEASTRIM1genetic
20093466
YD183_YEASTYDL183Cgenetic
20093466
UME6_YEASTUME6genetic
20093466
BCS1_YEASTBCS1genetic
20093466
RLA4_YEASTRPP2Bgenetic
20093466
BUD27_YEASTBUD27genetic
20093466
RS27B_YEASTRPS27Bgenetic
20093466
DHOM_YEASTHOM6genetic
20093466
XPOT_YEASTLOS1genetic
20093466
SEC72_YEASTSEC72genetic
20093466
SPH1_YEASTSPH1genetic
20093466
ROM2_YEASTROM2genetic
20093466
VPS9_YEASTVPS9genetic
20093466
PET8_YEASTPET8genetic
20093466
COQ7_YEASTCAT5genetic
20093466
ELP4_YEASTELP4genetic
20093466
IWR1_YEASTIWR1genetic
21695216
RRP1_YEASTRRP1genetic
27708008
SEC7_YEASTSEC7genetic
27708008
ACT_YEASTACT1genetic
27708008
PSF2_YEASTPSF2genetic
27708008
NUF2_YEASTNUF2genetic
27708008
SEC8_YEASTSEC8genetic
27708008
TFC3_YEASTTFC3genetic
27708008
SYIC_YEASTILS1genetic
27708008
IPYR_YEASTIPP1genetic
27708008
CDK1_YEASTCDC28genetic
27708008
CDC10_YEASTCDC10genetic
27708008
NOP14_YEASTNOP14genetic
27708008
RPC10_YEASTRPC11genetic
27708008
MAK21_YEASTMAK21genetic
27708008
CDC1_YEASTCDC1genetic
27708008
TFC6_YEASTTFC6genetic
27708008
UTP5_YEASTUTP5genetic
27708008
SYF1_YEASTSYF1genetic
27708008
TSC11_YEASTTSC11genetic
27708008
MOB2_YEASTMOB2genetic
27708008
STT3_YEASTSTT3genetic
27708008
CDC12_YEASTCDC12genetic
27708008
RPC9_YEASTRPC17genetic
27708008
CDC11_YEASTCDC11genetic
27708008
BOS1_YEASTBOS1genetic
27708008
EI2BB_YEASTGCD7genetic
27708008
CDC3_YEASTCDC3genetic
27708008
TRM6_YEASTGCD10genetic
27708008
RPC6_YEASTRPC34genetic
27708008
RPC1_YEASTRPO31genetic
27708008
EI2BG_YEASTGCD1genetic
27708008
TFC8_YEASTTFC8genetic
27708008
RPC3_YEASTRPC82genetic
27708008
NU170_YEASTNUP170genetic
27708008
UME6_YEASTUME6genetic
27708008
BUD27_YEASTBUD27genetic
27708008
MRX5_YEASTYJL147Cgenetic
27708008
PIR5_YEASTYJL160Cgenetic
27708008
CYP7_YEASTCPR7genetic
27708008
DBR1_YEASTDBR1genetic
27708008
XPOT_YEASTLOS1genetic
27708008
COX12_YEASTCOX12genetic
27708008
VPS9_YEASTVPS9genetic
27708008
PEX12_YEASTPEX12genetic
27708008
RSF1_YEASTRSF1genetic
27708008
SWS2_YEASTSWS2genetic
27708008
ESBP6_YEASTESBP6genetic
27708008
COQ7_YEASTCAT5genetic
27708008
ELP4_YEASTELP4genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of RIT1_YEAST

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Related Literatures of Post-Translational Modification

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