dbPTM

RT04_YEAST - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	RT04_YEAST
UniProt AC	P32902
Protein Name	37S ribosomal protein MRP4, mitochondrial
Gene Name	MRP4
Organism	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length	394
Subcellular Localization	Mitochondrion . Mitoribosomes are tethered to the mitochondrial inner membrane and spatially aligned with the membrane insertion machinery through two distinct membrane contact sites, formed by the 21S rRNA expansion segment 96-ES1 and the inner memb
Protein Description	Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane..
Protein Sequence	MQRHVFARNFRRLSLLRNPSLTKRFQSSASGAANTPNNNDEVMLLQQKLLYDEIRSELKSLSQVPEDEILPELKKSLEQDKLSDKEQQLEAELSDFFRNYALLNKLFDSKTLDGQSSTTTAAATPTKPYPNLIPSANDKPYSSQELFLRQLNHSMRTAKLGATISKVYYPHKDIFYPPLPENITVESLMSAGVHLGQSTSLWRSSTQSYIYGEYKGIHIIDLNQTLSYLKRAAKVVEGVSESGGIILFLGTRQGQKRGLEEAAKKTHGYYVSTRWIPGTLTNSTEISGIWEKQEIDSNDNPTERALSPNETSKQVKPDLLVVLNPTENRNALLEAIKSRVPTIAIIDTDSEPSLVTYPIPGNDDSLRSVNFLLGVLARAGQRGLQNRLARNNEK

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
60	Phosphorylation	EIRSELKSLSQVPED HHHHHHHHHHCCCHH	45.97	27214570
76	Phosphorylation	ILPELKKSLEQDKLS HHHHHHHHHHHCCCC	35.24	29136822
105	Acetylation	RNYALLNKLFDSKTL HHHHHHHHHHCCCCC	50.96	24489116
154	Phosphorylation	FLRQLNHSMRTAKLG HHHHHHHHHHHHHHC	14.64	26447709
157	Phosphorylation	QLNHSMRTAKLGATI HHHHHHHHHHHCCEE	21.36	26447709
163	Phosphorylation	RTAKLGATISKVYYP HHHHHCCEEEECCCC	24.80	26447709
165	Phosphorylation	AKLGATISKVYYPHK HHHCCEEEECCCCCC	16.24	26447709
230	Acetylation	NQTLSYLKRAAKVVE HHHHHHHHHHHHHHH	31.58	24489116
311	Phosphorylation	RALSPNETSKQVKPD CCCCCCCCCCCCCCC	48.11	24930733
312	Phosphorylation	ALSPNETSKQVKPDL CCCCCCCCCCCCCCE	18.21	24930733

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of RT04_YEAST !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of RT04_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of RT04_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
HSC82_YEAST	HSC82	physical	11805826
RT01_YEAST	MRP1	physical	11805826
RT13_YEAST	MRP13	physical	11805826
RT21_YEAST	MRP21	physical	11805826
RT51_YEAST	MRP51	physical	11805826
RT28_YEAST	MRPS28	physical	11805826
RT05_YEAST	MRPS5	physical	11805826
RT09_YEAST	MRPS9	physical	11805826
NAM9_YEAST	NAM9	physical	11805826
RTPT_YEAST	PET123	physical	11805826
RT10_YEAST	RSM10	physical	11805826
RT19_YEAST	RSM19	physical	11805826
RT22_YEAST	RSM22	physical	11805826
RT23_YEAST	RSM23	physical	11805826
RT25_YEAST	RSM25	physical	11805826
RT26_YEAST	RSM26	physical	11805826
RT27_YEAST	RSM27	physical	11805826
RT07_YEAST	RSM7	physical	11805826
HIBCH_YEAST	EHD3	physical	11805826
RT08_YEAST	MRPS8	physical	11805826
RT17_YEAST	MRPS17	physical	11805826
RT18_YEAST	MRPS18	physical	11805826
PUS7_YEAST	PUS7	physical	11805826
IMG1_YEAST	IMG1	physical	12392552
IMG2_YEAST	IMG2	physical	12392552
RT01_YEAST	MRP1	physical	12392552
RT13_YEAST	MRP13	physical	12392552
RT06_YEAST	MRP17	physical	12392552
RT02_YEAST	MRP2	physical	12392552
RT21_YEAST	MRP21	physical	12392552
RM02_YEAST	MRP7	physical	12392552
RM01_YEAST	MRPL1	physical	12392552
RM15_YEAST	MRPL15	physical	12392552
RM17_YEAST	MRPL17	physical	12392552
RM20_YEAST	MRPL20	physical	12392552
RM22_YEAST	MRPL22	physical	12392552
RM23_YEAST	MRPL23	physical	12392552
RM25_YEAST	MRPL25	physical	12392552
RM27_YEAST	MRPL27	physical	12392552
RM03_YEAST	MRPL3	physical	12392552
RM31_YEAST	MRPL31	physical	12392552
RM35_YEAST	MRPL35	physical	12392552
RM36_YEAST	MRPL36	physical	12392552
RM38_YEAST	MRPL38	physical	12392552
RM40_YEAST	MRPL40	physical	12392552
RN49_YEAST	MRPL49	physical	12392552
RM50_YEAST	MRPL50	physical	12392552
RM51_YEAST	MRPL51	physical	12392552
RM06_YEAST	MRPL6	physical	12392552
RM08_YEAST	MRPL8	physical	12392552
RT17_YEAST	MRPS17	physical	12392552
RT18_YEAST	MRPS18	physical	12392552
RT28_YEAST	MRPS28	physical	12392552
RT35_YEAST	MRPS35	physical	12392552
RT05_YEAST	MRPS5	physical	12392552
RT08_YEAST	MRPS8	physical	12392552
RT09_YEAST	MRPS9	physical	12392552
NAM9_YEAST	NAM9	physical	12392552
RTPT_YEAST	PET123	physical	12392552
RT10_YEAST	RSM10	physical	12392552
RT19_YEAST	RSM19	physical	12392552
RT22_YEAST	RSM22	physical	12392552
RT23_YEAST	RSM23	physical	12392552
RT24_YEAST	RSM24	physical	12392552
RT25_YEAST	RSM25	physical	12392552
RT26_YEAST	RSM26	physical	12392552
RT27_YEAST	RSM27	physical	12392552
RT07_YEAST	RSM7	physical	12392552
RMAR_YEAST	VAR1	physical	12392552
EIF3A_YEAST	RPG1	physical	16554755
RT24_YEAST	RSM24	physical	16554755
IF2G_YEAST	GCD11	physical	16554755
RT23_YEAST	RSM23	physical	16554755
PYR1_YEAST	URA2	physical	16554755
CBF1_YEAST	CBF1	physical	16554755
IMDH3_YEAST	IMD3	physical	16554755
CCL1_YEAST	CCL1	physical	16554755
HIBCH_YEAST	EHD3	physical	16429126
RT01_YEAST	MRP1	physical	16429126
RT13_YEAST	MRP13	physical	16429126
RT21_YEAST	MRP21	physical	16429126
RT51_YEAST	MRP51	physical	16429126
RT17_YEAST	MRPS17	physical	16429126
RT18_YEAST	MRPS18	physical	16429126
RT28_YEAST	MRPS28	physical	16429126
RT05_YEAST	MRPS5	physical	16429126
RT08_YEAST	MRPS8	physical	16429126
RT09_YEAST	MRPS9	physical	16429126
NAM9_YEAST	NAM9	physical	16429126
RTPT_YEAST	PET123	physical	16429126
PUS7_YEAST	PUS7	physical	16429126
RT10_YEAST	RSM10	physical	16429126
RT22_YEAST	RSM22	physical	16429126
RT23_YEAST	RSM23	physical	16429126
RT25_YEAST	RSM25	physical	16429126
RT26_YEAST	RSM26	physical	16429126
RT07_YEAST	RSM7	physical	16429126
RT19_YEAST	RSM19	physical	16429126
RT27_YEAST	RSM27	physical	16429126
DED1_YEAST	DED1	physical	16429126
GET3_YEAST	GET3	physical	11283351
ATG17_YEAST	ATG17	physical	11283351
BBP1_YEAST	BBP1	physical	11283351
MUM2_YEAST	MUM2	physical	18719252
SIF2_YEAST	SIF2	physical	18719252
COG2_YEAST	COG2	physical	18719252
ATG17_YEAST	ATG17	physical	18719252
HUA2_YEAST	HUA2	physical	18719252
SYF1_YEAST	SYF1	physical	18719252
ADA2_YEAST	ADA2	physical	18719252
MDV1_YEAST	MDV1	physical	18719252
NDC80_HUMAN	NDC80	physical	27107014
MARE3_HUMAN	MAPRE3	physical	27107014
NECA2_HUMAN	NECAB2	physical	27107014
DYDC1_HUMAN	DYDC1	physical	27107014
MAGA8_HUMAN	MAGEA8	physical	27107014
CEP70_HUMAN	CEP70	physical	27107014
MYOME_HUMAN	PDE4DIP	physical	27107014
UBX11_HUMAN	UBXN11	physical	27107014
ATRIP_HUMAN	ATRIP	physical	27107014
MTUS2_HUMAN	MTUS2	physical	27107014
USBP1_HUMAN	USHBP1	physical	27107014
SPERT_HUMAN	SPERT	physical	27107014
RPGR1_HUMAN	RPGRIP1	physical	27107014
CCDB1_HUMAN	CCNDBP1	physical	27107014
LDOC1_HUMAN	LDOC1	physical	27107014
HEM1_HUMAN	ALAS1	physical	27107014
MR1L1_HUMAN	MRFAP1L1	physical	27107014
CA050_HUMAN	C1orf50	physical	27107014
CACO2_HUMAN	CALCOCO2	physical	27107014
TEX11_HUMAN	TEX11	physical	27107014
HOOK2_HUMAN	HOOK2	physical	27107014
RBPMS_HUMAN	RBPMS	physical	27107014
TRI23_HUMAN	TRIM23	physical	27107014
TTC12_HUMAN	TTC12	physical	27107014

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of RT04_YEAST

Related Literatures of Post-Translational Modification