| UniProt ID | SEG2_YEAST | |
|---|---|---|
| UniProt AC | P34250 | |
| Protein Name | Eisosome protein SEG2 | |
| Gene Name | SEG2 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 1132 | |
| Subcellular Localization |
Cell membrane Peripheral membrane protein Cytoplasmic side . Localizes to eisosomes. |
|
| Protein Description | Likely plays only a minor role in eisosome assembly.. | |
| Protein Sequence | MIQESSPDALAAAAAIGNALSYNGRTVDKSKIPQYNQSFTSRTTSIAGINRYTMLSNSRTNSRMLLMNGNVRQYSKRTSSLPNQGHKNTSNNSAGRRQHRAHEDAETTFREFGGKQSSKVLNISSSTGQNSKSRTTSLGNSGSTIRTIKKYIPGPRGLMAVEVPVEVEPPRYSLSNRSNQRGGRAYSLPTRNNKTSLMHRNKTTKKAGSQEKKSESGGKSKNDYHGKVLSKMHTTSLKQRHNNVPLIPTTMNEETEQELQEDLHDPLEFKPMIISDDENSFIEPSVLDRSIPKKDKSGLSGREKKEEIETLLKEVHSLEEKISNIEIAKLNEEEREQSLILELRKVKLDEERRMELLKRELNIVKENADLEAQELKLIESKRKQHFHKGQEVASEVKSITIRQPTLSEPKPAYVPPEDVEKEPSTLSNQTQNIENAENIDSVDAEGNLVDPILLGSLNNSNFHMNSDNEVRCIADSNSLTGSELSDYNYIEGSATDLRATAKTSVESEIGGNQVGLKIPQDDDSEKQEERTKGKKSGLVDTNCFLVQKEDQEEALSDNEPESSEKFPSTSGIENVKLEDETGSVMDKNNGPNNDKDDDDDKDNDNDDDDDKDDDVNDDDKDENVDDDENVDDDDDDDDDDDDEYHDSYDVIMRDPVQIEQDISDVPSLKHPSEYSTETEDNKKKEQNSENAEVSQSGTNMAKYLRGANPYLTNTSSDTFSLDSENVNSKSSTDTTRVAPDLLKSSLQPQLRSDLKQSAVPSSTSSSIYSIETSPNIDSSTGKTASNTKTNSHGPPTSISKQKYDQSSSHQIPVMSPKRLDDKRKITNRSCLRTLRGSSNEATLSHNIVYPASDSSSSPPYHSKKPSNPPSSGNLASHEASKCFPKAPQASTTSRRLPDHVPLYIDKNNSALYPKEPPARKSSFEKERPAKDNLGFRSMSLREPLITKNATATAAENLDVEEKKEKGGHVSRKSWTFGLPSPLKRRTSHSTHTTNETEIVNPMTNFKNKTNENDMPILANKKSCNNDDSSPYTASSMNTNDVSEAGTEGHRFSLFGNKSQLSNRNISGGTATLESSNPDLPTALPLSVPVTIIDKNGEIHKLHNDDAAIKDKSHDRHGHSKFGRKLKKIFGRK | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 30 | Phosphorylation | NGRTVDKSKIPQYNQ CCEECCHHHCCCCCC | 29136822 | ||
| 35 | Phosphorylation | DKSKIPQYNQSFTSR CHHHCCCCCCCCCCC | 29136822 | ||
| 38 | Phosphorylation | KIPQYNQSFTSRTTS HCCCCCCCCCCCCCC | 29136822 | ||
| 40 | Phosphorylation | PQYNQSFTSRTTSIA CCCCCCCCCCCCCCC | 29136822 | ||
| 41 | Phosphorylation | QYNQSFTSRTTSIAG CCCCCCCCCCCCCCC | 29136822 | ||
| 43 | Phosphorylation | NQSFTSRTTSIAGIN CCCCCCCCCCCCCCC | 22369663 | ||
| 44 | Phosphorylation | QSFTSRTTSIAGINR CCCCCCCCCCCCCCC | 19779198 | ||
| 45 | Phosphorylation | SFTSRTTSIAGINRY CCCCCCCCCCCCCCE | 22369663 | ||
| 52 | Phosphorylation | SIAGINRYTMLSNSR CCCCCCCEEEEECCC | 19779198 | ||
| 56 | Phosphorylation | INRYTMLSNSRTNSR CCCEEEEECCCCCCE | 22369663 | ||
| 58 | Phosphorylation | RYTMLSNSRTNSRML CEEEEECCCCCCEEE | 22369663 | ||
| 78 | Phosphorylation | VRQYSKRTSSLPNQG HHHHHHCCCCCCCCC | 22890988 | ||
| 79 | Phosphorylation | RQYSKRTSSLPNQGH HHHHHCCCCCCCCCC | 22890988 | ||
| 80 | Phosphorylation | QYSKRTSSLPNQGHK HHHHCCCCCCCCCCC | 19823750 | ||
| 127 | Phosphorylation | VLNISSSTGQNSKSR EEEEECCCCCCCCCC | 19684113 | ||
| 131 | Phosphorylation | SSSTGQNSKSRTTSL ECCCCCCCCCCCEEC | 28889911 | ||
| 133 | Phosphorylation | STGQNSKSRTTSLGN CCCCCCCCCCEECCC | 22369663 | ||
| 135 | Phosphorylation | GQNSKSRTTSLGNSG CCCCCCCCEECCCCC | 22369663 | ||
| 136 | Phosphorylation | QNSKSRTTSLGNSGS CCCCCCCEECCCCCH | 22369663 | ||
| 137 | Phosphorylation | NSKSRTTSLGNSGST CCCCCCEECCCCCHH | 22369663 | ||
| 141 | Phosphorylation | RTTSLGNSGSTIRTI CCEECCCCCHHHHHH | 22369663 | ||
| 143 | Phosphorylation | TSLGNSGSTIRTIKK EECCCCCHHHHHHHH | 22369663 | ||
| 144 | Phosphorylation | SLGNSGSTIRTIKKY ECCCCCHHHHHHHHH | 22369663 | ||
| 147 | Phosphorylation | NSGSTIRTIKKYIPG CCCHHHHHHHHHCCC | 19823750 | ||
| 149 | Ubiquitination | GSTIRTIKKYIPGPR CHHHHHHHHHCCCCC | 24961812 | ||
| 172 | Phosphorylation | VEVEPPRYSLSNRSN CEECCCCCCCCCCCC | 22369663 | ||
| 173 | Phosphorylation | EVEPPRYSLSNRSNQ EECCCCCCCCCCCCC | 22369663 | ||
| 175 | Phosphorylation | EPPRYSLSNRSNQRG CCCCCCCCCCCCCCC | 22369663 | ||
| 186 | Phosphorylation | NQRGGRAYSLPTRNN CCCCCCCCCCCCCCC | 22890988 | ||
| 187 | Phosphorylation | QRGGRAYSLPTRNNK CCCCCCCCCCCCCCC | 22369663 | ||
| 234 | Phosphorylation | KVLSKMHTTSLKQRH HHHHHHCCCCHHHHH | 23749301 | ||
| 236 | Phosphorylation | LSKMHTTSLKQRHNN HHHHCCCCHHHHHCC | 21440633 | ||
| 275 | Phosphorylation | EFKPMIISDDENSFI CCCCEEEECCCCCCC | 27214570 | ||
| 280 | Phosphorylation | IISDDENSFIEPSVL EEECCCCCCCCHHHH | 27214570 | ||
| 313 | Ubiquitination | EEIETLLKEVHSLEE HHHHHHHHHHHCHHH | 17644757 | ||
| 317 | Phosphorylation | TLLKEVHSLEEKISN HHHHHHHCHHHHHHC | 25521595 | ||
| 321 | Ubiquitination | EVHSLEEKISNIEIA HHHCHHHHHHCCCHH | 17644757 | ||
| 323 | Phosphorylation | HSLEEKISNIEIAKL HCHHHHHHCCCHHHC | 24961812 | ||
| 398 | Phosphorylation | EVASEVKSITIRQPT HHHHHCCEEEEECCC | 23749301 | ||
| 400 | Phosphorylation | ASEVKSITIRQPTLS HHHCCEEEEECCCCC | 21440633 | ||
| 500 | Phosphorylation | SATDLRATAKTSVES CCCCHHHHCCCCEEE | 22369663 | ||
| 503 | Phosphorylation | DLRATAKTSVESEIG CHHHHCCCCEEEECC | 22369663 | ||
| 504 | Phosphorylation | LRATAKTSVESEIGG HHHHCCCCEEEECCC | 22369663 | ||
| 507 | Phosphorylation | TAKTSVESEIGGNQV HCCCCEEEECCCEEE | 22369663 | ||
| 524 | Phosphorylation | KIPQDDDSEKQEERT ECCCCCCHHHHHHHH | 25005228 | ||
| 526 | Ubiquitination | PQDDDSEKQEERTKG CCCCCHHHHHHHHHC | 22106047 | ||
| 556 | Phosphorylation | EDQEEALSDNEPESS HHHHHHHHCCCCCHH | 22369663 | ||
| 562 | Phosphorylation | LSDNEPESSEKFPST HHCCCCCHHCCCCCC | 22890988 | ||
| 563 | Phosphorylation | SDNEPESSEKFPSTS HCCCCCHHCCCCCCC | 22890988 | ||
| 568 | Phosphorylation | ESSEKFPSTSGIENV CHHCCCCCCCCCCCE | 19779198 | ||
| 570 | Phosphorylation | SEKFPSTSGIENVKL HCCCCCCCCCCCEEE | 28889911 | ||
| 581 | Phosphorylation | NVKLEDETGSVMDKN CEEEECCCCCCCCCC | 22890988 | ||
| 583 | Phosphorylation | KLEDETGSVMDKNNG EEECCCCCCCCCCCC | 22369663 | ||
| 663 | Phosphorylation | VQIEQDISDVPSLKH CCCCCCCCCCCCCCC | 22890988 | ||
| 667 | Phosphorylation | QDISDVPSLKHPSEY CCCCCCCCCCCHHHC | 22890988 | ||
| 672 | Phosphorylation | VPSLKHPSEYSTETE CCCCCCHHHCCCCCC | 22369663 | ||
| 674 | Phosphorylation | SLKHPSEYSTETEDN CCCCHHHCCCCCCCH | 22369663 | ||
| 675 | Phosphorylation | LKHPSEYSTETEDNK CCCHHHCCCCCCCHH | 22369663 | ||
| 676 | Phosphorylation | KHPSEYSTETEDNKK CCHHHCCCCCCCHHH | 22369663 | ||
| 678 | Phosphorylation | PSEYSTETEDNKKKE HHHCCCCCCCHHHHH | 22369663 | ||
| 688 | Phosphorylation | NKKKEQNSENAEVSQ HHHHHHCCCCCCHHH | 22369663 | ||
| 694 | Phosphorylation | NSENAEVSQSGTNMA CCCCCCHHHHHHHHH | 23749301 | ||
| 696 | Phosphorylation | ENAEVSQSGTNMAKY CCCCHHHHHHHHHHH | 22369663 | ||
| 698 | Phosphorylation | AEVSQSGTNMAKYLR CCHHHHHHHHHHHHC | 22369663 | ||
| 702 | Ubiquitination | QSGTNMAKYLRGANP HHHHHHHHHHCCCCC | 23749301 | ||
| 714 | Phosphorylation | ANPYLTNTSSDTFSL CCCCCCCCCCCCCCC | 29734811 | ||
| 715 | Phosphorylation | NPYLTNTSSDTFSLD CCCCCCCCCCCCCCC | 22369663 | ||
| 716 | Phosphorylation | PYLTNTSSDTFSLDS CCCCCCCCCCCCCCC | 21440633 | ||
| 718 | Phosphorylation | LTNTSSDTFSLDSEN CCCCCCCCCCCCCCC | 21440633 | ||
| 720 | Phosphorylation | NTSSDTFSLDSENVN CCCCCCCCCCCCCCC | 20377248 | ||
| 723 | Phosphorylation | SDTFSLDSENVNSKS CCCCCCCCCCCCCCC | 24961812 | ||
| 728 | Phosphorylation | LDSENVNSKSSTDTT CCCCCCCCCCCCCCC | 24961812 | ||
| 730 | Phosphorylation | SENVNSKSSTDTTRV CCCCCCCCCCCCCCC | 24961812 | ||
| 731 | Phosphorylation | ENVNSKSSTDTTRVA CCCCCCCCCCCCCCC | 21551504 | ||
| 732 | Phosphorylation | NVNSKSSTDTTRVAP CCCCCCCCCCCCCCH | 24961812 | ||
| 734 | Phosphorylation | NSKSSTDTTRVAPDL CCCCCCCCCCCCHHH | 24961812 | ||
| 735 | Phosphorylation | SKSSTDTTRVAPDLL CCCCCCCCCCCHHHH | 21551504 | ||
| 743 | Ubiquitination | RVAPDLLKSSLQPQL CCCHHHHHHCCCHHH | 23749301 | ||
| 762 | Phosphorylation | KQSAVPSSTSSSIYS HHHCCCCCCCCCEEE | 21551504 | ||
| 763 | Phosphorylation | QSAVPSSTSSSIYSI HHCCCCCCCCCEEEE | 21551504 | ||
| 782 | Ubiquitination | NIDSSTGKTASNTKT CCCCCCCCCCCCCCC | 17644757 | ||
| 788 | Ubiquitination | GKTASNTKTNSHGPP CCCCCCCCCCCCCCC | 17644757 | ||
| 791 | Phosphorylation | ASNTKTNSHGPPTSI CCCCCCCCCCCCCCC | 23749301 | ||
| 796 | Phosphorylation | TNSHGPPTSISKQKY CCCCCCCCCCCCCCC | 23749301 | ||
| 797 | Phosphorylation | NSHGPPTSISKQKYD CCCCCCCCCCCCCCC | 21551504 | ||
| 799 | Phosphorylation | HGPPTSISKQKYDQS CCCCCCCCCCCCCCC | 21551504 | ||
| 803 | Phosphorylation | TSISKQKYDQSSSHQ CCCCCCCCCCCCCCC | 28889911 | ||
| 806 | Phosphorylation | SKQKYDQSSSHQIPV CCCCCCCCCCCCCCC | 21551504 | ||
| 807 | Phosphorylation | KQKYDQSSSHQIPVM CCCCCCCCCCCCCCC | 21440633 | ||
| 808 | Phosphorylation | QKYDQSSSHQIPVMS CCCCCCCCCCCCCCC | 21440633 | ||
| 815 | Phosphorylation | SHQIPVMSPKRLDDK CCCCCCCCCCCCCCC | 21551504 | ||
| 852 | Phosphorylation | HNIVYPASDSSSSPP CCEEEECCCCCCCCC | 23749301 | ||
| 854 | Phosphorylation | IVYPASDSSSSPPYH EEEECCCCCCCCCCC | 23749301 | ||
| 855 | Phosphorylation | VYPASDSSSSPPYHS EEECCCCCCCCCCCC | 23749301 | ||
| 856 | Phosphorylation | YPASDSSSSPPYHSK EECCCCCCCCCCCCC | 23749301 | ||
| 857 | Phosphorylation | PASDSSSSPPYHSKK ECCCCCCCCCCCCCC | 27017623 | ||
| 860 | Phosphorylation | DSSSSPPYHSKKPSN CCCCCCCCCCCCCCC | 23749301 | ||
| 866 | Phosphorylation | PYHSKKPSNPPSSGN CCCCCCCCCCCCCCC | 20377248 | ||
| 870 | Phosphorylation | KKPSNPPSSGNLASH CCCCCCCCCCCCCCH | 21440633 | ||
| 871 | Phosphorylation | KPSNPPSSGNLASHE CCCCCCCCCCCCCHH | 19823750 | ||
| 876 | Phosphorylation | PSSGNLASHEASKCF CCCCCCCCHHHHHCC | 21551504 | ||
| 880 | Phosphorylation | NLASHEASKCFPKAP CCCCHHHHHCCCCCC | 19823750 | ||
| 909 | Phosphorylation | LYIDKNNSALYPKEP EEECCCCCCCCCCCC | 24909858 | ||
| 921 | Phosphorylation | KEPPARKSSFEKERP CCCCCCCCCCCCCCC | 21440633 | ||
| 922 | Phosphorylation | EPPARKSSFEKERPA CCCCCCCCCCCCCCC | 24909858 | ||
| 939 | Phosphorylation | NLGFRSMSLREPLIT CCCCCCCCCCCCCCC | 21440633 | ||
| 950 | Phosphorylation | PLITKNATATAAENL CCCCCCCCCHHHHHC | 19823750 | ||
| 952 | Phosphorylation | ITKNATATAAENLDV CCCCCCCHHHHHCCH | 19823750 | ||
| 973 | Phosphorylation | GGHVSRKSWTFGLPS CCCCCCCCEECCCCC | 22890988 | ||
| 975 | Phosphorylation | HVSRKSWTFGLPSPL CCCCCCEECCCCCCC | 22890988 | ||
| 980 | Phosphorylation | SWTFGLPSPLKRRTS CEECCCCCCCCCCCC | 22890988 | ||
| 986 | Phosphorylation | PSPLKRRTSHSTHTT CCCCCCCCCCCCCCC | 19779198 | ||
| 987 | Phosphorylation | SPLKRRTSHSTHTTN CCCCCCCCCCCCCCC | 17330950 | ||
| 989 | Phosphorylation | LKRRTSHSTHTTNET CCCCCCCCCCCCCCC | 19779198 | ||
| 990 | Phosphorylation | KRRTSHSTHTTNETE CCCCCCCCCCCCCCE | 19779198 | ||
| 992 | Phosphorylation | RTSHSTHTTNETEIV CCCCCCCCCCCCEEE | 19779198 | ||
| 993 | Phosphorylation | TSHSTHTTNETEIVN CCCCCCCCCCCEEEC | 19779198 | ||
| 996 | Phosphorylation | STHTTNETEIVNPMT CCCCCCCCEEECCCC | 19779198 | ||
| 1022 | Phosphorylation | PILANKKSCNNDDSS CEECCCCCCCCCCCC | 28889911 | ||
| 1034 | Phosphorylation | DSSPYTASSMNTNDV CCCCCCHHHCCCCCC | 23749301 | ||
| 1035 | Phosphorylation | SSPYTASSMNTNDVS CCCCCHHHCCCCCCH | 23749301 | ||
| 1038 | Phosphorylation | YTASSMNTNDVSEAG CCHHHCCCCCCHHCC | 23749301 | ||
| 1058 | Phosphorylation | FSLFGNKSQLSNRNI EECCCCHHHHCCCCC | 23749301 | ||
| 1061 | Phosphorylation | FGNKSQLSNRNISGG CCCHHHHCCCCCCCC | 23749301 | ||
| 1066 | Phosphorylation | QLSNRNISGGTATLE HHCCCCCCCCCEECC | 22369663 | ||
| 1069 | Phosphorylation | NRNISGGTATLESSN CCCCCCCCEECCCCC | 22369663 | ||
| 1071 | Phosphorylation | NISGGTATLESSNPD CCCCCCEECCCCCCC | 23749301 | ||
| 1074 | Phosphorylation | GGTATLESSNPDLPT CCCEECCCCCCCCCC | 22369663 | ||
| 1075 | Phosphorylation | GTATLESSNPDLPTA CCEECCCCCCCCCCC | 23749301 | ||
| 1081 | Phosphorylation | SSNPDLPTALPLSVP CCCCCCCCCCEEECE | 21440633 | ||
| 1086 | Phosphorylation | LPTALPLSVPVTIID CCCCCEEECEEEEEC | 22369663 | ||
| 1090 | Phosphorylation | LPLSVPVTIIDKNGE CEEECEEEEECCCCC | 22369663 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of SEG2_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of SEG2_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of SEG2_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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