LPX1_YEAST - dbPTM
LPX1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID LPX1_YEAST
UniProt AC Q12405
Protein Name Peroxisomal membrane protein LPX1
Gene Name LPX1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 387
Subcellular Localization Peroxisome matrix . Peroxisomal import is dependent on the peroxisomal targeting signal type 1 (PTS1) receptor PEX5 and on self-interaction.
Protein Description Has acyl esterase, lipase and phospholipase A activity..
Protein Sequence MEQNRFKKETKTCSASWPRAPQSTLCATDRLELTYDVYTSAERQRRSRTATRLNLVFLHGSGMSKVVWEYYLPRLVAADAEGNYAIDKVLLIDQVNHGDSAVRNRGRLGTNFNWIDGARDVLKIATCELGSIDSHPALNVVIGHSMGGFQALACDVLQPNLFHLLILIEPVVITRKAIGAGRPGLPPDSPQIPENLYNSLRLKTCDHFANESEYVKYMRNGSFFTNAHSQILQNIIDFERTKASGDDEDGGPVRTKMEQAQNLLCYMNMQTFAPFLISNVKFVRKRTIHIVGARSNWCPPQNQLFLQKTLQNYHLDVIPGGSHLVNVEAPDLVIERINHHIHEFVLTSPLQSSHIPQLTLEERAVMFDRAFDSFKNEALVKTTKQKL
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
12PhosphorylationRFKKETKTCSASWPR
CCCCCCCCCCCCCCC
21.0728889911
14PhosphorylationKKETKTCSASWPRAP
CCCCCCCCCCCCCCC
30.4828889911
16PhosphorylationETKTCSASWPRAPQS
CCCCCCCCCCCCCCC
22.7128889911

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of LPX1_YEAST !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of LPX1_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of LPX1_YEAST !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
LPX1_YEASTLPX1physical
18199283
LPX1_YEASTLPX1physical
21741480
FAT1_YEASTFAT1genetic
27708008
YB8B_YEASTYBR287Wgenetic
27708008
BUD31_YEASTBUD31genetic
27708008
TREA_YEASTNTH1genetic
27708008
RAD4_YEASTRAD4genetic
27708008
MRM2_YEASTMRM2genetic
27708008
THI4_YEASTTHI4genetic
27708008
BUB1_YEASTBUB1genetic
27708008
HTD2_YEASTHTD2genetic
27708008
CRP1_YEASTCRP1genetic
27708008
SFGH_YEASTYJL068Cgenetic
27708008
FABG_YEASTOAR1genetic
27708008
PRR1_YEASTPRR1genetic
27708008
KIN2_YEASTKIN2genetic
27708008
ADY4_YEASTADY4genetic
27708008
GAS1_YEASTGAS1genetic
27708008
MSO1_YEASTMSO1genetic
27708008
INO4_YEASTINO4genetic
27708008
PMA2_YEASTPMA2genetic
27708008
PCL8_YEASTPCL8genetic
27708008

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of LPX1_YEAST

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Related Literatures of Post-Translational Modification

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