VBA1_YEAST - dbPTM
VBA1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID VBA1_YEAST
UniProt AC Q04301
Protein Name Vacuolar basic amino acid transporter 1
Gene Name VBA1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 562
Subcellular Localization Vacuole membrane
Multi-pass membrane protein .
Protein Description Transporter required for vacuolar uptake of at least histidine and lysine..
Protein Sequence MQTLDETSNLLPPPEEAEAPPLEQKFHEYNLALPKFPILFSLWLGSFLSSLDSTIVANIMNRVAEEFSESSKKQWIATSFLLTNTAFQPLYGKLSDITGRKSALLTAQFFFGLGCLLTCFARNVTEFSIARAICGIGAGGLNAISSIAVSDICTARERGVYQGYANIVFGFGQLLGAPLGGVFIETIGWRALFGIQVPVIMLCSVLAIKNINIKLFHVPPMKERYTLKNLSRIDIFGSLSLVATISGVLFLCSSQLNKLYLALFTIGSFIVFILVERYYATEKILPFELLTRSFCLSSAVTVISSFVVFGEIFRSPIYLQLLQNISVTKTGLFLIFPSISVAVGSLVTGWVLRNTKINLAHCAYQIIFGGMIMQLLGLGLGYFLLSHLNPDYTIYDMLESITFRSNSIWWKLIYVFASVLVSFGYACLLVATLVSIVFTVEKSQQGTMTGVFYLWRSIGNVLGASLTLVSYENSLSSMLWNYMFKTKRDDEYHFTKKQYYSLINDSSYLRGPNFPTDIFVRILDVYKKAFLISYIPNIALAAVGIVLSLYLVKHTYKRSSSS
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
25UbiquitinationEAPPLEQKFHEYNLA
CCCCHHHHHHHHCCC		39.0324961812
78PhosphorylationSKKQWIATSFLLTNT
HHHHHHHHHHHHHCC		15.7527017623
79PhosphorylationKKQWIATSFLLTNTA
HHHHHHHHHHHHCCC		12.6027017623
83PhosphorylationIATSFLLTNTAFQPL
HHHHHHHHCCCCHHH		32.4419779198
85PhosphorylationTSFLLTNTAFQPLYG
HHHHHHCCCCHHHHH		24.5019779198
91PhosphorylationNTAFQPLYGKLSDIT
CCCCHHHHHHHHHCC		20.9227017623
123N-linked_GlycosylationLLTCFARNVTEFSIA
HHHHHHCCCCHHHHH		41.45-
324N-linked_GlycosylationIYLQLLQNISVTKTG
HHHHHHHHCCCCCCE		28.59-
471PhosphorylationASLTLVSYENSLSSM
CEEEEEECCCCHHHH		16.2027017623
474PhosphorylationTLVSYENSLSSMLWN
EEEECCCCHHHHHHH		20.0727017623
476PhosphorylationVSYENSLSSMLWNYM
EECCCCHHHHHHHHH		17.3327017623
477PhosphorylationSYENSLSSMLWNYMF
ECCCCHHHHHHHHHH		24.1627017623
482PhosphorylationLSSMLWNYMFKTKRD
HHHHHHHHHHCCCCC		7.7327017623
504N-linked_GlycosylationKQYYSLINDSSYLRG
HHHHHHHCCHHHHCC		48.70-
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of VBA1_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of VBA1_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of VBA1_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
VBA2_YEASTVBA2genetic
15572352
MNN9_YEASTMNN9physical
16093310
USO1_YEASTUSO1genetic
27708008
SEC7_YEASTSEC7genetic
27708008
ACT_YEASTACT1genetic
27708008
PSF2_YEASTPSF2genetic
27708008
FNTA_YEASTRAM2genetic
27708008
SEC8_YEASTSEC8genetic
27708008
MRM2_YEASTMRM2genetic
27708008
AIM18_YEASTAIM18genetic
27708008
BFA1_YEASTBFA1genetic
27708008
SEC17_YEASTSEC17genetic
27708008
CKS1_YEASTCKS1genetic
27708008
APC11_YEASTAPC11genetic
27708008
DPOD_YEASTPOL3genetic
27708008
NSE4_YEASTNSE4genetic
27708008
NOP14_YEASTNOP14genetic
27708008
MAK21_YEASTMAK21genetic
27708008
SC61G_YEASTSSS1genetic
27708008
ERF3_YEASTSUP35genetic
27708008
GPI11_YEASTGPI11genetic
27708008
BCP1_YEASTBCP1genetic
27708008
MOB2_YEASTMOB2genetic
27708008
NBP35_YEASTNBP35genetic
27708008
GPI1_YEASTGPI1genetic
27708008
XPO1_YEASTCRM1genetic
27708008
TAF1_YEASTTAF1genetic
27708008
BRL1_YEASTBRL1genetic
27708008
CDC12_YEASTCDC12genetic
27708008
MET30_YEASTMET30genetic
27708008
MCM10_YEASTMCM10genetic
27708008
PRI1_YEASTPRI1genetic
27708008
ARP4_YEASTARP4genetic
27708008
TIM16_YEASTPAM16genetic
27708008
CDC6_YEASTCDC6genetic
27708008
YJ9I_YEASTYJR141Wgenetic
27708008
RSC4_YEASTRSC4genetic
27708008
BET3_YEASTBET3genetic
27708008
TIM14_YEASTPAM18genetic
27708008
RSC58_YEASTRSC58genetic
27708008
CFT2_YEASTCFT2genetic
27708008
NEP1_YEASTEMG1genetic
27708008
SEC22_YEASTSEC22genetic
27708008
GSP1_YEASTGSP1genetic
27708008
NOP2_YEASTNOP2genetic
27708008
DPOA_YEASTPOL1genetic
27708008
DCP2_YEASTDCP2genetic
27708008
DBP6_YEASTDBP6genetic
27708008
HRP1_YEASTHRP1genetic
27708008
PSB5_YEASTPRE2genetic
27708008
YAJ9_YEASTYAR029Wgenetic
27708008
H3_YEASTHHT1genetic
27708008
RKM3_YEASTRKM3genetic
27708008
SWC5_YEASTSWC5genetic
27708008
SHG1_YEASTSHG1genetic
27708008
ATG15_YEASTATG15genetic
27708008
AAD4_YEASTAAD4genetic
27708008
MNN10_YEASTMNN10genetic
27708008
DBF2_YEASTDBF2genetic
27708008
PUR91_YEASTADE16genetic
27708008
ARP6_YEASTARP6genetic
27708008
PET8_YEASTPET8genetic
27708008
PFD4_YEASTGIM3genetic
27708008
YN92_YEASTYNR063Wgenetic
27708008
NEW1_YEASTNEW1genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of VBA1_YEAST

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Related Literatures of Post-Translational Modification

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