TYR1_YEAST - dbPTM
TYR1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID TYR1_YEAST
UniProt AC P20049
Protein Name Prephenate dehydrogenase [NADP(+)]
Gene Name TYR1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 452
Subcellular Localization
Protein Description
Protein Sequence MVSEDKIEQWKATKVIGIIGLGDMGLLYANKFTDAGWGVICCDREEYYDELKEKYASAKFELVKNGHLVSRQSDYIIYSVEASNISKIVATYGPSSKVGTIVGGQTSCKLPEIEAFEKYLPKDCDIITVHSLHGPKVNTEGQPLVIINHRSQYPESFEFVNSVMACLKSKQVYLTYEEHDKITADTQAVTHAAFLSMGSAWAKIKIYPWTLGVNKWYGGLENVKVNISLRIYSNKWHVYAGLAITNPSAHQQILQYATSATELFSLMIDNKEQELTDRLLKAKQFVFGKHTGLLLLDDTILEKYSLSKSSIGNSNNCKPVPNSHLSLLAIVDSWFQLGIDPYDHMICSTPLFRIFLGVSEYLFLKPGLLEQTIDAAIHDKSFIKDDLEFVISAREWSSVVSFANFDIYKKQFQSVQKFFEPMLPEANLIGNEMIKTILSHSSDRSAAEKRNT
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
59AcetylationKEKYASAKFELVKNG
HHHHHHCCEEEEECC		36.5524489116
97UbiquitinationATYGPSSKVGTIVGG
EEECCCCCCEEEECC		49.3623749301
118AcetylationPEIEAFEKYLPKDCD
CCHHHHHHHCCCCCC		45.7124489116
239PhosphorylationYSNKWHVYAGLAITN
ECCCEEEEEEEEECC		5.1030377154
245PhosphorylationVYAGLAITNPSAHQQ
EEEEEEECCHHHHHH		35.1530377154
258PhosphorylationQQILQYATSATELFS
HHHHHHHHCHHHHHH		17.6030377154
259PhosphorylationQILQYATSATELFSL
HHHHHHHCHHHHHHH		25.6430377154
265PhosphorylationTSATELFSLMIDNKE
HCHHHHHHHHCCCCC		29.6530377154
410UbiquitinationANFDIYKKQFQSVQK
CCCHHHHHHHHHHHH		39.1023749301
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of TYR1_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of TYR1_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of TYR1_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
KPC1_YEASTPKC1physical
16554755
SSB2_YEASTSSB2physical
16554755
TYR1_YEASTTYR1physical
18719252
6PGD1_YEASTGND1genetic
21623372
CHMU_YEASTARO7genetic
21623372
ERG6_YEASTERG6genetic
21623372
THDH_YEASTILV1genetic
21623372
AROC_YEASTARO2genetic
21623372
ATPO_YEASTATP5genetic
21623372
GGPPS_YEASTBTS1genetic
21623372
DCOR_YEASTSPE1genetic
21623372
ACT_YEASTACT1genetic
27708008
UBP6_YEASTUBP6genetic
27708008
VAM7_YEASTVAM7genetic
27708008
PRP9_YEASTPRP9genetic
27708008
CDC1_YEASTCDC1genetic
27708008
CND3_YEASTYCG1genetic
27708008
GDI1_YEASTGDI1genetic
27708008
COG3_YEASTCOG3genetic
27708008
SYYC_YEASTTYS1genetic
27708008
RRP41_YEASTSKI6genetic
27708008
CP51_YEASTERG11genetic
27708008
FDFT_YEASTERG9genetic
27708008
IF2A_YEASTSUI2genetic
27708008
CDC11_YEASTCDC11genetic
27708008
BET3_YEASTBET3genetic
27708008
POB3_YEASTPOB3genetic
27708008
RNA14_YEASTRNA14genetic
27708008
SPC24_YEASTSPC24genetic
27708008
RNA1_YEASTRNA1genetic
27708008
LST8_YEASTLST8genetic
27708008
NOG2_YEASTNOG2genetic
27708008
SGT1_YEASTSGT1genetic
27708008
GRPE_YEASTMGE1genetic
27708008
YAJ9_YEASTYAR029Wgenetic
27708008
SGF29_YEASTSGF29genetic
27708008
RV161_YEASTRVS161genetic
27708008
PP2C1_YEASTPTC1genetic
27708008
SND1_YEASTYDR186Cgenetic
27708008
UME6_YEASTUME6genetic
27708008
GNTK_YEASTYDR248Cgenetic
27708008
STP1_YEASTSTP1genetic
27708008
PCL6_YEASTPCL6genetic
27708008
CEM1_YEASTCEM1genetic
27708008
ICP55_YEASTICP55genetic
27708008
UBP3_YEASTUBP3genetic
27708008
OSW7_YEASTOSW7genetic
27708008
CSK2B_YEASTCKB1genetic
27708008
AAKG_YEASTSNF4genetic
27708008
GCN1_YEASTGCN1genetic
27708008
TAN1_YEASTTAN1genetic
27708008
CGS6_YEASTCLB6genetic
27708008
UBCX_YEASTPEX4genetic
27708008
SNF6_YEASTSNF6genetic
27708008
STP2_YEASTSTP2genetic
27708008
CRP1_YEASTCRP1genetic
27708008
CSK21_YEASTCKA1genetic
27708008
FYV10_YEASTFYV10genetic
27708008
FMC1_YEASTFMC1genetic
27708008
DAL81_YEASTDAL81genetic
27708008
SNX4_YEASTSNX4genetic
27708008
LPLA_YEASTAIM22genetic
27708008
MNN11_YEASTMNN11genetic
27708008
FABG_YEASTOAR1genetic
27708008
COXM1_YEASTCMC1genetic
27708008
NU133_YEASTNUP133genetic
27708008
SIC1_YEASTSIC1genetic
27708008
PEX13_YEASTPEX13genetic
27708008
LIPB_YEASTLIP2genetic
27708008
GAS2_YEASTGAS2genetic
27708008
ATP10_YEASTATP10genetic
27708008
ECM30_YEASTECM30genetic
27708008
SOK2_YEASTSOK2genetic
27708008
PEX12_YEASTPEX12genetic
27708008
ERG2_YEASTERG2genetic
27708008
HFA1_YEASTHFA1genetic
27708008
MAS5_YEASTYDJ1genetic
27708008
YNN4_YEASTYNL134Cgenetic
27708008
EAF7_YEASTEAF7genetic
27708008
PP2A4_YEASTPPG1genetic
27708008
YO087_YEASTDUF1genetic
27708008
AZF1_YEASTAZF1genetic
27708008
ENV9_YEASTENV9genetic
27708008
PMT3_YEASTPMT3genetic
27708008
MNE1_YEASTMNE1genetic
27708008
CHL1_YEASTCHL1genetic
27708008
RAD1_YEASTRAD1genetic
27708008
BECN1_YEASTVPS30genetic
27708008
ATG5_YEASTATG5genetic
27708008
PPQ1_YEASTPPQ1genetic
27708008
MRL1_YEASTMRL1genetic
27708008
PIAS2_HUMANPIAS2physical
27107014
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of TYR1_YEAST

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Related Literatures of Post-Translational Modification

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