SPR28_YEAST - dbPTM
SPR28_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID SPR28_YEAST
UniProt AC Q04921
Protein Name Sporulation-regulated protein 28
Gene Name SPR28
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 423
Subcellular Localization Membrane
Peripheral membrane protein. Bud neck. Present at the bud neck during cell division. Probably interacts with phosphoinosides such as phosphatidylinositol 4-phosphate or phosphatidylinositol 5-phosphate (By similarity). Localizes to ring-lik
Protein Description Septins are GTPases involved in cytokinesis that assemble into filaments and form a ring at the cleavage site. May act by recruiting MYO1 and HOF1, a protein involved in septation, to the site of cleavage. Septins are also involved in cell morphogenesis, bud site selection, chitin deposition, cell cycle regulation, cell compartmentalization and spore wall formation (By similarity)..
Protein Sequence MFPMKDHSALEQHTLSRDELRRRKGYKKGLQLSILLLGEKGSGKSTFLNNLCGQDISLSDGDYDDDDDKVTNNVTPENGNAIEDIDPGYKTAHLSPGLKLVTRRVYLNDELGVPITLDIILFPGCGDNVDNSQSSVVIKNYLDQQFANVLKEEVRIKRNTKETDGRPHVCLYFLKSTPRGVKKFDIELMKTICDKVNLIPIIPKADGLTETELNLHKDIVRQEISQNNIRVFDFKSDTLGETLALYDMDIDSSSAKSKYDNDTKIKEISPFAIVCSKTFNKNSENRVEHIRTYEWGSLVVEDQNTSDFIYLKAILLGSHLQELKDVTNNVLYENYRAKVLTEKKNNYDIPNYSYIDETSRGSVSNVSTRRNSASRTLGNPDTNDENAYQIHKEIDEKNRIIEDYQRKIDLLEKMLAAPHQNKV
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
259PhosphorylationSSSAKSKYDNDTKIK
CHHHHHCCCCCCCCE		27.3728889911
292PhosphorylationNRVEHIRTYEWGSLV
CCCEEEEEEEEECEE		25.7827017623
305PhosphorylationLVVEDQNTSDFIYLK
EEECCCCCCCHHHHH		24.8427017623
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of SPR28_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of SPR28_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of SPR28_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
CDC11_YEASTCDC11physical
10688190
SPR28_YEASTSPR28physical
8885406
SEC22_YEASTSEC22genetic
23891562
RPN4_YEASTRPN4genetic
27708008
MTU1_YEASTSLM3genetic
27708008
GPR1_YEASTGPR1genetic
27708008
TRM3_YEASTTRM3genetic
27708008
BCS1_YEASTBCS1genetic
27708008
RAD4_YEASTRAD4genetic
27708008
YFF1_YEASTYFL051Cgenetic
27708008
CHO2_YEASTCHO2genetic
27708008
PTH_YEASTPTH1genetic
27708008
PIR5_YEASTYJL160Cgenetic
27708008
YJ24_YEASTKCH1genetic
27708008
CBT1_YEASTCBT1genetic
27708008
POM33_YEASTPOM33genetic
27708008
ATP10_YEASTATP10genetic
27708008
MSS1_YEASTMSS1genetic
27708008
RAD14_YEASTRAD14genetic
27708008
PET8_YEASTPET8genetic
27708008
LSM7_YEASTLSM7genetic
27708008
MNE1_YEASTMNE1genetic
27708008
HAP5_YEASTHAP5genetic
27708008
PPAL_YEASTLTP1genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of SPR28_YEAST

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Related Literatures of Post-Translational Modification

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