DAZP2_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: DAZP2_HUMAN
• UniProt AC: Q15038
• Protein Name: DAZ-associated protein 2
• Gene Name: DAZAP2
• Organism: Homo sapiens (Human).
• Sequence Length: 168
• Subcellular Localization: Cytoplasm. Nucleus. Predominantly nuclear in macrophages, stimulation of IL17RB with its ligand IL17E induces accumulation in the cytoplasm.
• Protein Sequence: MNSKGQYPTQPTYPVQPPGNPVYPQTLHLPQAPPYTDAPPAYSELYRPSFVHPGAATVPTMSAAFPGASLYLPMAQSVAVGPLGSTIPMAYYPVGPIYPPGSTVLVEGGYDAGARFGAGATAGNIPPPPPGCPPNAAQLAVMQGANVLVTQRKGNFFMGGSDGGYTIW

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
110	Phosphorylation	TVLVEGGYDAGARFG EEEEECCCCCCCCCC	17.30	-
131	Ubiquitination	NIPPPPPGCPPNAAQ CCCCCCCCCCCCHHH	42.19	21906983
153	Ubiquitination	NVLVTQRKGNFFMGG CEEEEECCCCEEECC	48.68	21906983
161	Phosphorylation	GNFFMGGSDGGYTIW CCEEECCCCCCCCCC	27.61	25348954
165	Phosphorylation	MGGSDGGYTIW---- ECCCCCCCCCC----	10.69	28796482
166	Phosphorylation	GGSDGGYTIW----- CCCCCCCCCC-----	21.43	28796482

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of DAZP2_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of DAZP2_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of DAZP2_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
DCNL1_HUMAN	DCUN1D1	physical	16189514
DAZP2_HUMAN	DAZAP2	physical	16189514
CA094_HUMAN	C1orf94	physical	16189514
FA46C_HUMAN	FAM46C	physical	16189514
BATF2_HUMAN	BATF2	physical	16189514
STAM2_HUMAN	STAM2	physical	16189514
POLI_HUMAN	POLI	physical	16189514
ZN581_HUMAN	ZNF581	physical	16189514
AATF_HUMAN	AATF	physical	16189514
TOLIP_HUMAN	TOLLIP	physical	16189514
ZFN2B_HUMAN	ZFAND2B	physical	16189514
NOC4L_HUMAN	NOC4L	physical	16189514
RFOX2_HUMAN	RBFOX2	physical	16189514
UBAC1_HUMAN	UBAC1	physical	16189514
RHXF2_HUMAN	RHOXF2	physical	16189514
MUT7_HUMAN	EXD3	physical	16189514
CACO2_HUMAN	CALCOCO2	physical	16189514
WWP1_HUMAN	WWP1	physical	16189514
RBPMS_HUMAN	RBPMS	physical	16189514
GPSM1_HUMAN	GPSM1	physical	16189514
CC120_HUMAN	CCDC120	physical	16189514
DAZL_HUMAN	DAZL	physical	10857750
DAZ1_HUMAN	DAZ1	physical	10857750
TF7L2_HUMAN	TCF7L2	physical	19304756
CTNB1_HUMAN	CTNNB1	physical	19304756
LEF1_HUMAN	LEF1	physical	19304756
TCF7_HUMAN	TCF7	physical	19304756
TF7L1_HUMAN	TCF7L1	physical	19304756
RL40_HUMAN	UBA52	physical	21900206
CEP70_HUMAN	CEP70	physical	21900206
CO4A2_HUMAN	COL4A2	physical	21900206
SQSTM_HUMAN	SQSTM1	physical	21900206
CDK4_HUMAN	CDK4	physical	21900206
WDR73_HUMAN	WDR73	physical	21900206
MED31_HUMAN	MED31	physical	21900206
TLE1_HUMAN	TLE1	physical	21900206
CO4A5_HUMAN	COL4A5	physical	21900206
FBN3_HUMAN	FBN3	physical	21900206
SMUF2_HUMAN	SMURF2	physical	22070932
DAZP2_HUMAN	DAZAP2	physical	25416956
OPTN_HUMAN	OPTN	physical	25416956
CACO2_HUMAN	CALCOCO2	physical	25416956
STAM2_HUMAN	STAM2	physical	25416956
UBAC1_HUMAN	UBAC1	physical	25416956
ARI5A_HUMAN	ARID5A	physical	25416956
RBPMS_HUMAN	RBPMS	physical	25416956
CLASR_HUMAN	CLASRP	physical	25416956
POGZ_HUMAN	POGZ	physical	25416956
F168A_HUMAN	FAM168A	physical	25416956
NED4L_HUMAN	NEDD4L	physical	25416956
RFOX2_HUMAN	RBFOX2	physical	25416956
RN115_HUMAN	RNF115	physical	25416956
RABX5_HUMAN	RABGEF1	physical	25416956
EPN1_HUMAN	EPN1	physical	25416956
UB2D4_HUMAN	UBE2D4	physical	25416956
UBS3A_HUMAN	UBASH3A	physical	25416956
DCNL1_HUMAN	DCUN1D1	physical	25416956
TOLIP_HUMAN	TOLLIP	physical	25416956
PKHB2_HUMAN	PLEKHB2	physical	25416956
VP37C_HUMAN	VPS37C	physical	25416956
SMAP2_HUMAN	SMAP2	physical	25416956
TNIP3_HUMAN	TNIP3	physical	25416956
ZNF34_HUMAN	ZNF34	physical	25416956
RHXF2_HUMAN	RHOXF2	physical	25416956
UBS3B_HUMAN	UBASH3B	physical	25416956
CA094_HUMAN	C1orf94	physical	25416956
OTUL_HUMAN	OTULIN	physical	25416956
PR20E_HUMAN	PRR20A	physical	25416956
PR20C_HUMAN	PRR20A	physical	25416956
PR20D_HUMAN	PRR20A	physical	25416956
PR20B_HUMAN	PRR20A	physical	25416956
PR20A_HUMAN	PRR20A	physical	25416956
ZFN2B_HUMAN	ZFAND2B	physical	25416956
TEX37_HUMAN	TEX37	physical	25416956
KRA81_HUMAN	KRTAP8-1	physical	25416956
KR195_HUMAN	KRTAP19-5	physical	25416956
VHLL_HUMAN	VHLL	physical	25416956
RN208_HUMAN	RNF208	physical	25416956

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.