VHLL_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: VHLL_HUMAN
• UniProt AC: Q6RSH7
• Protein Name: von Hippel-Lindau-like protein
• Gene Name: VHLL
• Organism: Homo sapiens (Human).
• Sequence Length: 139
• Protein Description: Functions as a dominant-negative VHL to serve as a protector of HIFalpha..
• Protein Sequence: MPWRAGNGVGLEAQAGTQEAGPEEYCQEELGAEEEMAARAAWPVLRSVNSRELSRIIICNHSPRIVLPVWLNYYGKLLPYLTLLPGRDFRIHNFRSHPWLFRDARTHDKLLVNQTELFVPSSNVNGQPVFANITLQCIP

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
47	Phosphorylation	AAWPVLRSVNSRELS HHHHHHHCCCCCCCC	22.84	24719451
80	Phosphorylation	YYGKLLPYLTLLPGR HHHHHHHHHHCCCCC	16.58	-
82	Phosphorylation	GKLLPYLTLLPGRDF HHHHHHHHCCCCCCC	22.02	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of VHLL_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of VHLL_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of VHLL_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
HIF1A_HUMAN	HIF1A	physical	14757845

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.