RN208_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RN208_HUMAN
• UniProt AC: Q9H0X6
• Protein Name: RING finger protein 208
• Gene Name: RNF208
• Organism: Homo sapiens (Human).
• Sequence Length: 261
• Protein Sequence: MPSDPGPEAGSGWPGLLMSCLKGPHVILKMEAMKIVHPEKFPELPAAPCFPPAPRPTPTLAPKRAWPSDTEIIVNQACGGDMPALEGAPHTPPLPRRPRKGSSELGFPRVAPEDEVIVNQYVIRPGPSASAASSAAAGEPLECPTCGHSYNVTQRRPRVLSCLHSVCEQCLQILYESCPKYKFISCPTCRRETVLFTDYGLAALAVNTSILSRLPPEALTAPSGGQWGAEPEGSCYQTFRQYCGAACTCHVRNPLSACSIM

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
102	Phosphorylation	PRRPRKGSSELGFPR CCCCCCCCCCCCCCC	24.55	22617229
103	Phosphorylation	RRPRKGSSELGFPRV CCCCCCCCCCCCCCC	45.57	30108239
181	Phosphorylation	LYESCPKYKFISCPT HHHHCCCCCEEECCC	9.04	-
209	Phosphorylation	AALAVNTSILSRLPP HHHHHCHHHHHCCCH	19.14	24719451
212	Phosphorylation	AVNTSILSRLPPEAL HHCHHHHHCCCHHHH	30.05	24719451

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RN208_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RN208_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RN208_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of RN208_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Quantitative phosphoproteomic analysis of T cell receptor signalingreveals system-wide modulation of protein-protein interactions.";
Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K.,Rodionov V., Han D.K.;
Sci. Signal. 2:RA46-RA46(2009).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-102, AND MASSSPECTROMETRY.
PubMed: 19690332