ZNF34_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZNF34_HUMAN
• UniProt AC: Q8IZ26
• Protein Name: Zinc finger protein 34
• Gene Name: ZNF34
• Organism: Homo sapiens (Human).
• Sequence Length: 560
• Subcellular Localization: Nucleus .
• Protein Description: May be involved in transcriptional regulation..
• Protein Sequence: MLLLLSDQLLLTALRKPNPQAMAALFLSAPPQAEVTFEDVAVYLSREEWGRLGPAQRGLYRDVMLETYGNLVSLGVGPAGPKPGVISQLERGDEPWVLDVQGTSGKEHLRVNSPALGTRTEYKELTSQETFGEEDPQGSEPVEACDHISKSEGSLEKLVEQRGPRAVTLTNGESSRESGGNLRLLSRPVPDQRPHKCDICEQSFEQRSYLNNHKRVHRSKKTNTVRNSGEIFSANLVVKEDQKIPTGKKLHYCSYCGKTFRYSANLVKHQRLHTEEKPYKCDECGKAFSQSCEFINHRRMHSGEIPYRCDECGKTFTRRPNLMKHQRIHTGEKPYKCGECGKHFSAYSSLIYHQRIHTGEKPYKCNDCGKAFSDGSILIRHRRTHTGEKPFECKECGKGFTQSSNLIQHQRIHTGEKPYKCNECEKAFIQKTKLVEHQRSHTGEKPYECNDCGKVFSQSTHLIQHQRIHTGEKPYKCSECGKAFHNSSRLIHHQRLHHGEKPYRCSDCKKAFSQSTYLIQHRRIHTGEKPYKCSECGKAFRHSSNMCQHQRIHLREDFSM

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
12	Phosphorylation	LSDQLLLTALRKPNP HHHHHHHHHHHCCCH	24.50	24719451
67	Phosphorylation	YRDVMLETYGNLVSL HHHHHHHHHCCCEEC	32.54	20068231
68	Phosphorylation	RDVMLETYGNLVSLG HHHHHHHHCCCEECC	8.47	20068231
73	Phosphorylation	ETYGNLVSLGVGPAG HHHCCCEECCCCCCC	23.67	20068231
87	Phosphorylation	GPKPGVISQLERGDE CCCCCCEEECCCCCC	26.72	20068231
113	Phosphorylation	KEHLRVNSPALGTRT CCCEEECCCCCCCCH	14.53	25159151
118	Phosphorylation	VNSPALGTRTEYKEL ECCCCCCCCHHHHHH	34.96	23312004
222	Phosphorylation	RVHRSKKTNTVRNSG CCCCCCCCCCCCCCC	39.60	-
224	Phosphorylation	HRSKKTNTVRNSGEI CCCCCCCCCCCCCCE	26.52	-
262	Phosphorylation	YCGKTFRYSANLVKH CCCCEEEEECHHHHH	14.14	-
263	Phosphorylation	CGKTFRYSANLVKHQ CCCEEEEECHHHHHC	13.36	-
302	Phosphorylation	INHRRMHSGEIPYRC CCCCCCCCCCCCCCC	28.86	28555341
324	Acetylation	TRRPNLMKHQRIHTG CCCCCCCCCCCCCCC	39.49	19815649
330	Phosphorylation	MKHQRIHTGEKPYKC CCCCCCCCCCCCEEC	44.67	29496963
336	Sumoylation	HTGEKPYKCGECGKH CCCCCCEECCCCCCC	44.27	-
336	Sumoylation	HTGEKPYKCGECGKH CCCCCCEECCCCCCC	44.27	-
358	Phosphorylation	IYHQRIHTGEKPYKC HHHCCCCCCCCCEEC	44.67	29496963
373	Phosphorylation	NDCGKAFSDGSILIR CCCCCCCCCCCEEEE	46.02	29759185
376	Phosphorylation	GKAFSDGSILIRHRR CCCCCCCCEEEEECC	21.15	29759185
384	Phosphorylation	ILIRHRRTHTGEKPF EEEEECCCCCCCCCC	24.60	-
386	Phosphorylation	IRHRRTHTGEKPFEC EEECCCCCCCCCCCC	46.56	21857030
389	Ubiquitination	RRTHTGEKPFECKEC CCCCCCCCCCCCCCC	57.25	-
394	Sumoylation	GEKPFECKECGKGFT CCCCCCCCCCCCCCC	49.17	-
394	Sumoylation	GEKPFECKECGKGFT CCCCCCCCCCCCCCC	49.17	-
414	Phosphorylation	IQHQRIHTGEKPYKC CCCCEECCCCCCCCC	44.67	29496963
470	Phosphorylation	IQHQRIHTGEKPYKC HCCCCCCCCCCCEEC	44.67	29496963
504	Methylation	HHGEKPYRCSDCKKA CCCCCCCCCHHHHHH	23.22	115387611
526	Phosphorylation	IQHRRIHTGEKPYKC EECCCCCCCCCCEEC	44.67	29496963
544	Phosphorylation	GKAFRHSSNMCQHQR HHHHHHCCCCCHHCE	23.58	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZNF34_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZNF34_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZNF34_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.