RHXF2_HUMAN - dbPTM
RHXF2_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID RHXF2_HUMAN
UniProt AC Q9BQY4
Protein Name Rhox homeobox family member 2
Gene Name RHOXF2 {ECO:0000312|HGNC:HGNC:30011}
Organism Homo sapiens (Human).
Sequence Length 288
Subcellular Localization Nucleus .
Protein Description Transcription factor maybe involved in reproductive processes. Modulates expression of target genes encoding proteins involved in processes relevant to spermatogenesis..
Protein Sequence MEPPDQCSQYMTSLLSPAVDDEKELQDMNAMVLSLTEEVKEEEEDAQPEPEQGTAAGEKLKSAGAQGGEEKDGGGEEKDGGGAGVPGHLWEGDLEGTSGSDGNVEDSDQSEKEPGQQYSRPQGAVGGLEPGNAQQPNVHAFTPLQLQELERIFQREQFPSEFLRRRLARSMNVTELAVQIWFENRRAKWRRHQRALMARNMLPFMAVGQPVMVTAAEAITAPLFISGMRDDYFWDHSHSSSLCFPMPPFPPPSLPLPLMLLPPMPPAGQAEFGPFPFVIVPSFTFPNV
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
97PhosphorylationWEGDLEGTSGSDGNV
EECCCCCCCCCCCCC
22.1222210691
98PhosphorylationEGDLEGTSGSDGNVE
ECCCCCCCCCCCCCC
47.3523186163
100PhosphorylationDLEGTSGSDGNVEDS
CCCCCCCCCCCCCCC
41.9523917254
107PhosphorylationSDGNVEDSDQSEKEP
CCCCCCCCCCCCCCC
24.8422210691
110PhosphorylationNVEDSDQSEKEPGQQ
CCCCCCCCCCCCCCC
56.4822210691
214PhosphorylationVGQPVMVTAAEAITA
CCCCEEEEHHHHHHH
11.3124043423
220PhosphorylationVTAAEAITAPLFISG
EEHHHHHHHHHHCCC
29.3024043423
226PhosphorylationITAPLFISGMRDDYF
HHHHHHCCCCCCCCC
21.1424043423

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of RHXF2_HUMAN !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of RHXF2_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of RHXF2_HUMAN !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
LENG8_HUMANLENG8physical
16189514
DTX2_HUMANDTX2physical
16189514
FA46D_HUMANFAM46Dphysical
16189514
FBF1_HUMANFBF1physical
16189514
NEUR4_HUMANNEU4physical
16189514
RHXF2_HUMANRHOXF2physical
16189514
FA46B_HUMANFAM46Bphysical
16189514
DEDD2_HUMANDEDD2physical
20211142
DAZP2_HUMANDAZAP2physical
19060904
PCH2_HUMANTRIP13physical
19060904
RHXF2_HUMANRHOXF2physical
25416956
HNRLL_HUMANHNRNPLLphysical
25416956
NEUR4_HUMANNEU4physical
25416956
KR195_HUMANKRTAP19-5physical
25416956
KR197_HUMANKRTAP19-7physical
25416956
ARMX2_HUMANARMCX2physical
21516116

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of RHXF2_HUMAN

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Related Literatures of Post-Translational Modification

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