SMD3_YEAST - dbPTM
SMD3_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID SMD3_YEAST
UniProt AC P43321
Protein Name Small nuclear ribonucleoprotein Sm D3
Gene Name SMD3
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 101
Subcellular Localization Cytoplasm . Nucleus .
Protein Description Involved in pre-mRNA splicing. Binds snRNA U1, U2, U4 and U5 which contain a highly conserved structural motif called the Sm binding site. Also binds telomerase RNA and is required for its accumulation..
Protein Sequence MTMNGIPVKLLNEAQGHIVSLELTTGATYRGKLVESEDSMNVQLRDVIATEPQGAVTHMDQIFVRGSQIKFIVVPDLLKNAPLFKKNSSRPMPPIRGPKRR
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster

Oops, there are no PTM records of SMD3_YEAST !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of SMD3_YEAST !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of SMD3_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of SMD3_YEAST !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
RSMB_YEASTSMB1physical
10428970
CDC12_YEASTCDC12physical
9207794
MTD1_YEASTMTD1physical
9207794
REV7_YEASTREV7physical
9207794
SEN1_YEASTSEN1physical
9207794
SPA2_YEASTSPA2physical
9207794
RSMB_YEASTSMB1physical
9207794
STB5_YEASTSTB5physical
9207794
VBA1_YEASTVBA1physical
9207794
PP2B1_YEASTCNA1physical
9207794
RAD16_YEASTRAD16physical
9207794
SNU66_YEASTSNU66physical
10377396
PRP6_YEASTPRP6physical
16554755
PRP9_YEASTPRP9physical
16554755
ARG56_YEASTARG5,6physical
16554755
RSE1_YEASTRSE1physical
16554755
RU1A_YEASTMUD1genetic
24497193
MUD2_YEASTMUD2genetic
24497193
SMD1_YEASTSMD1genetic
27974620
SMD2_YEASTSMD2genetic
27974620
RUXF_YEASTSMX3genetic
27417296
MUD2_YEASTMUD2genetic
25897024
RU1A_YEASTMUD1genetic
25897024
NAM8_YEASTNAM8genetic
25897024
TGS1_YEASTTGS1genetic
25897024
RSMB_YEASTSMB1genetic
25897024
RU2A_YEASTLEA1genetic
25897024

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of SMD3_YEAST

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Related Literatures of Post-Translational Modification

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