SUI1_YEAST - dbPTM
SUI1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID SUI1_YEAST
UniProt AC P32911
Protein Name Eukaryotic translation initiation factor eIF-1
Gene Name SUI1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 108
Subcellular Localization
Protein Description Additional factor that functions in concert with eIF-2 and the initiator tRNA in directing the ribosome to the proper start site of translation..
Protein Sequence MSIENLKSFDPFADTGDDETATSNYIHIRIQQRNGRKTLTTVQGVPEEYDLKRILKVLKKDFACNGNIVKDPEMGEIIQLQGDQRAKVCEFMISQLGLQKKNIKIHGF
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
2Phosphorylation------MSIENLKSF
------CCCCCHHCC		38.3124909858
2Acetylation------MSIENLKSF
------CCCCCHHCC		38.3122814378
7Ubiquitination-MSIENLKSFDPFAD
-CCCCCHHCCCCCCC		61.7424961812
7Acetylation-MSIENLKSFDPFAD
-CCCCCHHCCCCCCC		61.7425381059
8PhosphorylationMSIENLKSFDPFADT
CCCCCHHCCCCCCCC		37.7422369663
15PhosphorylationSFDPFADTGDDETAT
CCCCCCCCCCCCCCC		38.8022369663
20PhosphorylationADTGDDETATSNYIH
CCCCCCCCCCCCEEE		42.0828132839
22PhosphorylationTGDDETATSNYIHIR
CCCCCCCCCCEEEEE		25.5622369663
23PhosphorylationGDDETATSNYIHIRI
CCCCCCCCCEEEEEE		25.7722369663
25PhosphorylationDETATSNYIHIRIQQ
CCCCCCCEEEEEEEE		8.1422369663
37UbiquitinationIQQRNGRKTLTTVQG
EEEECCCCEEEEECC		49.6523749301
41PhosphorylationNGRKTLTTVQGVPEE
CCCCEEEEECCCCHH		17.5928889911
52UbiquitinationVPEEYDLKRILKVLK
CCHHHCHHHHHHHHH		34.2023749301
52AcetylationVPEEYDLKRILKVLK
CCHHHCHHHHHHHHH		34.2024489116
52SuccinylationVPEEYDLKRILKVLK
CCHHHCHHHHHHHHH		34.2023954790
60AcetylationRILKVLKKDFACNGN
HHHHHHHHHCCCCCC		54.6522865919
70UbiquitinationACNGNIVKDPEMGEI
CCCCCCCCCHHHCCE		64.8623749301
70AcetylationACNGNIVKDPEMGEI
CCCCCCCCCHHHCCE		64.8624489116
100AcetylationISQLGLQKKNIKIHG
HHHHCCCCCCCEECC		53.4824489116
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of SUI1_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of SUI1_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of SUI1_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
AATC_YEASTAAT2physical
11805837
SYLC_YEASTCDC60physical
11805837
SYG_YEASTGRS1physical
11805837
PDC5_YEASTPDC5physical
11805837
SYA_YEASTALA1physical
11805837
TRXB1_YEASTTRR1physical
11805837
ARLY_YEASTARG4physical
11805837
SYIC_YEASTILS1physical
11805837
ADH4_YEASTADH4physical
11805837
OAT_YEASTCAR2physical
11805837
CYPH_YEASTCPR1physical
11805837
KAR_YEASTYDL124Wphysical
11805837
THRC_YEASTTHR4physical
11805837
SSZ1_YEASTSSZ1physical
11805837
PSD10_YEASTNAS6physical
11805837
ACS2_YEASTACS2physical
11805837
ENP1_YEASTENP1physical
11805837
TPS1_YEASTTPS1physical
11805837
MPC54_YEASTMPC54physical
11805837
THIL_YEASTERG10physical
11805837
FPPS_YEASTERG20physical
11805837
SYNC_YEASTDED81physical
11805837
EIF3C_YEASTNIP1physical
11805837
EIF3I_YEASTTIF34physical
11805837
EIF3A_YEASTRPG1physical
11805837
EIF3G_YEASTTIF35physical
11805837
TRM6_YEASTGCD10physical
8628297
EIF3B_YEASTPRT1physical
8628297
IF4F2_YEASTTIF4632physical
12861028
EIF3I_YEASTTIF34physical
8628297
EIF3C_YEASTNIP1physical
11018020
EIF3C_YEASTNIP1physical
9660829
IF5_YEASTTIF5physical
15145951
IF5_YEASTTIF5physical
15377664
EI2BB_YEASTGCD7physical
15145951
EIF3I_YEASTTIF34physical
15145951
EIF3G_YEASTTIF35physical
15145951
EIF3C_YEASTNIP1physical
15485912
IF5_YEASTTIF5physical
12861028
EIF3C_YEASTNIP1genetic
15485912
IF2B_YEASTSUI3genetic
15485912
RV167_YEASTRVS167physical
16554755
PIL1_YEASTPIL1physical
16554755
CORO_YEASTCRN1physical
16554755
IF2A_YEASTSUI2physical
17974565
EIF3C_YEASTNIP1physical
17974565
IF5A1_YEASTHYP2physical
17974565
EIF3G_YEASTTIF35physical
17974565
IF5_YEASTTIF5genetic
19751744
IF1A_YEASTTIF11genetic
21930786
EIF3C_YEASTNIP1physical
22718758
IF4F1_YEASTTIF4631physical
22851688
RSSA1_YEASTRPS0Aphysical
22851688
IF1A_YEASTTIF11genetic
23893413
IF1A_YEASTTIF11physical
24335188
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of SUI1_YEAST

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Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"A multidimensional chromatography technology for in-depthphosphoproteome analysis.";
Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.;
Mol. Cell. Proteomics 7:1389-1396(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-22, AND MASSSPECTROMETRY.
"Proteome-wide identification of in vivo targets of DNA damagecheckpoint kinases.";
Smolka M.B., Albuquerque C.P., Chen S.H., Zhou H.;
Proc. Natl. Acad. Sci. U.S.A. 104:10364-10369(2007).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-15, AND MASSSPECTROMETRY.

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