| UniProt ID | ASI2_YEAST | |
|---|---|---|
| UniProt AC | P53895 | |
| Protein Name | Protein ASI2 | |
| Gene Name | ASI2 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 289 | |
| Subcellular Localization |
Nucleus inner membrane Multi-pass membrane protein . |
|
| Protein Description | Negative regulator of SPS-sensor signaling. Together with ASI1 and ASI3, prevents the unprocessed precursor forms of STP1 and STP2 that escape cytoplasmic anchoring from inducing SPS-sensor-regulated genes in the absence of inducing signals.. | |
| Protein Sequence | MARPQNHRRSNWTERDDNDDYLFQRFLEESETRHSREPSPVTEQSQQELQQDVQQAIDGIFNSLRRNMSSTSNINRAANMDATTNGNGGINADTIRATNANTADSPFTARQQSPLRTFLRNLFILDYFIGLILFPFSVYNILRSGFNSMTFSENDFIIEIVGYWKFAKIFGSGGTTLIAYKDTGKLGLLGKFHNIIVFYSSPVIKHIMKSRDGNEPNLNWIRLMFAKAFELFVKVSTILIYLAYGVSGTVYMVTAGFFFVLCLLFTVIRRYKGVHRMLVSQRITGPGVF | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 35 | Phosphorylation | EESETRHSREPSPVT HHHCCCCCCCCCCCC | 34.74 | 25704821 | |
| 69 | Phosphorylation | NSLRRNMSSTSNINR HHHHHHCCCCCCHHH | 33.73 | 22369663 | |
| 70 | Phosphorylation | SLRRNMSSTSNINRA HHHHHCCCCCCHHHH | 25.70 | 22369663 | |
| 71 | Phosphorylation | LRRNMSSTSNINRAA HHHHCCCCCCHHHHH | 20.63 | 22369663 | |
| 72 | Phosphorylation | RRNMSSTSNINRAAN HHHCCCCCCHHHHHC | 37.35 | 22369663 | |
| 105 | Phosphorylation | TNANTADSPFTARQQ CCCCCCCCCCCHHCC | 21.32 | 27214570 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of ASI2_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of ASI2_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of ASI2_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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