ECL1_YEAST - dbPTM
ECL1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID ECL1_YEAST
UniProt AC P48235
Protein Name Extender of the chronological lifespan protein 1
Gene Name ECL1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 211
Subcellular Localization
Protein Description Involved in chronological cell aging..
Protein Sequence MSTAFNDYCTVCDRLIPTSPQKTNINTRKIQRDNETKSSLQSNKLYCSEDCKLKDSNPLNEKLLSHLHKKSKTSHSHNLTPPLSYSKNLTASNLFEPTTSLSSSPTSSTIPFDELEKLESLLISPLLLPQDGIVNPKQESNPSRVDEYDENEHYLNLADSLRLDSSYQLHSKAHLGYENNLPRSNDLIDDHLISDQIIENNYNLWFRLSSS
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
2Phosphorylation------MSTAFNDYC
------CCCCHHHCC
28.5725521595
3Phosphorylation-----MSTAFNDYCT
-----CCCCHHHCCH
33.6925521595
18PhosphorylationVCDRLIPTSPQKTNI
HHCCCCCCCCCCCCC
46.1527214570
19PhosphorylationCDRLIPTSPQKTNIN
HCCCCCCCCCCCCCC
21.7025752575
124PhosphorylationKLESLLISPLLLPQD
HHHHHHHHCCCCCCC
14.9528132839
160PhosphorylationHYLNLADSLRLDSSY
CEEHHHHHCCCCCCE
15.1328132839

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of ECL1_YEAST !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of ECL1_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of ECL1_YEAST !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
CDC37_YEASTCDC37genetic
27708008
STU1_YEASTSTU1genetic
27708008
ORC2_YEASTORC2genetic
27708008
GDI1_YEASTGDI1genetic
27708008
GNA1_YEASTGNA1genetic
27708008
ACT_YEASTACT1genetic
27708008
RRP4_YEASTRRP4genetic
27708008
BIG1_YEASTBIG1genetic
27708008
STS1_YEASTSTS1genetic
27708008
SEC22_YEASTSEC22genetic
27708008
NAT10_YEASTKRE33genetic
27708008
CAP_YEASTSRV2genetic
27708008
SYA_YEASTALA1genetic
27708008
BUR1_YEASTSGV1genetic
27708008

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of ECL1_YEAST

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Related Literatures of Post-Translational Modification

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