| UniProt ID | ECL1_YEAST | |
|---|---|---|
| UniProt AC | P48235 | |
| Protein Name | Extender of the chronological lifespan protein 1 | |
| Gene Name | ECL1 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 211 | |
| Subcellular Localization | ||
| Protein Description | Involved in chronological cell aging.. | |
| Protein Sequence | MSTAFNDYCTVCDRLIPTSPQKTNINTRKIQRDNETKSSLQSNKLYCSEDCKLKDSNPLNEKLLSHLHKKSKTSHSHNLTPPLSYSKNLTASNLFEPTTSLSSSPTSSTIPFDELEKLESLLISPLLLPQDGIVNPKQESNPSRVDEYDENEHYLNLADSLRLDSSYQLHSKAHLGYENNLPRSNDLIDDHLISDQIIENNYNLWFRLSSS | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 2 | Phosphorylation | ------MSTAFNDYC ------CCCCHHHCC | 28.57 | 25521595 | |
| 3 | Phosphorylation | -----MSTAFNDYCT -----CCCCHHHCCH | 33.69 | 25521595 | |
| 18 | Phosphorylation | VCDRLIPTSPQKTNI HHCCCCCCCCCCCCC | 46.15 | 27214570 | |
| 19 | Phosphorylation | CDRLIPTSPQKTNIN HCCCCCCCCCCCCCC | 21.70 | 25752575 | |
| 124 | Phosphorylation | KLESLLISPLLLPQD HHHHHHHHCCCCCCC | 14.95 | 28132839 | |
| 160 | Phosphorylation | HYLNLADSLRLDSSY CEEHHHHHCCCCCCE | 15.13 | 28132839 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of ECL1_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of ECL1_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of ECL1_YEAST !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| CDC37_YEAST | CDC37 | genetic | 27708008 | |
| STU1_YEAST | STU1 | genetic | 27708008 | |
| ORC2_YEAST | ORC2 | genetic | 27708008 | |
| GDI1_YEAST | GDI1 | genetic | 27708008 | |
| GNA1_YEAST | GNA1 | genetic | 27708008 | |
| ACT_YEAST | ACT1 | genetic | 27708008 | |
| RRP4_YEAST | RRP4 | genetic | 27708008 | |
| BIG1_YEAST | BIG1 | genetic | 27708008 | |
| STS1_YEAST | STS1 | genetic | 27708008 | |
| SEC22_YEAST | SEC22 | genetic | 27708008 | |
| NAT10_YEAST | KRE33 | genetic | 27708008 | |
| CAP_YEAST | SRV2 | genetic | 27708008 | |
| SYA_YEAST | ALA1 | genetic | 27708008 | |
| BUR1_YEAST | SGV1 | genetic | 27708008 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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