SYTM_YEAST - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SYTM_YEAST
• UniProt AC: P07236
• Protein Name: Threonine--tRNA ligase, mitochondrial
• Gene Name: MST1
• Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
• Sequence Length: 462
• Subcellular Localization: Mitochondrion matrix.
• Protein Sequence: MKIQLVRWHCSRNALWNRAFYSTRKATKNASSATPATMTSMVSQRQDLFMTDPLSPGSMFFLPNGAKIFNKLIEFMKLQQKFKFGFNEVVTPLIYKKTLWEKSGHWENYADDMFKVETTDEEKEEYGLKPMNCPGHCLIFGKKDRSYNELPLRFSDFSPLHRNEASGALSGLTRLRKFHQDDGHIFCTPSQVKSEIFNSLKLIDIVYNKIFPFVKGGSGAESNYFINFSTRPDHFIGDLKVWNHAEQVLKEILEESGKPWKLNPGDGAFYGPKLDIMVTDHLRKTHQVATIQLDFQLPERFDLKFKDQDNSYKRPIMIHRATFGSIERFMALLIDSNEGRWPFWLNPYQAVIIPVNTKNVQQLDMCTALQKKLRNELEADDMEPVPLNDWHFNVDLDIRNEPVGYRIKSAILKNYSYLIIVGDEEVQLQKYNIRERDNRKSFEKLTMSQIWEKFIELEKNYK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
43	Phosphorylation	ATMTSMVSQRQDLFM HHHHHHHHHCCCCCC	15.82	27214570
158	Phosphorylation	PLRFSDFSPLHRNEA CCCCCCCCCCCCCHH	31.38	24930733

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SYTM_YEAST !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SYTM_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SYTM_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SYTM_YEAST	MST1	physical	22343532
SYTM_YEAST	MST1	physical	26704982

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.