PDR18_YEAST - dbPTM
PDR18_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID PDR18_YEAST
UniProt AC P53756
Protein Name ABC transporter ATP-binding protein/permease PDR18
Gene Name PDR18
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 1333
Subcellular Localization Membrane
Multi-pass membrane protein .
Protein Description
Protein Sequence MECVSVEGLDSSFLEGQTFGDILCLPWTIIKGIRERKNRNKMKIILKNVSLLAKSGEMVLVLGRPGAGCTSFLKSAAGETSQFAGGVTTGHISYDGIPQKEMMQHYKPDVIYNGEQDVHFPHLTVKQTLDFAISCKMPAKRVNNVTKEEYITANREFYAKIFGLTHTFDTKVGNDFISGVSGGERKRVSIAEALAAKGSIYCWDNATRGLDSSTALEFARAIRTMTNLLGTTALVTVYQASENIYETFDKVTVLYAGRQIFCGKTTEAKDYFENMGYLCPPRQSTAEYLTAITDPNGLHEIKPGFEYQVPHTADEFEKYWLDSPEYARLKGEIQKYKHEVNTEWTKKTYNESMAQEKSKGTRKKSYYTVSYWEQIRLCTIRGFLRIYGDKSYTVINTCAAIAQAFITGSLFYQAPSSTLGAFSRSGVLFFSLLYYSLMGLANISFEHRPILQKHKVYSLYHPSAEALASTISSFPFRMIGLTFFIIILYFLAGLHRSAGAFFTMYLLLTMCSEAITSLFQMVSSLCDTLSQANSIAGVVMLSIAMYSTYMIQLPSMHPWFKWISYILPIRYAFESMLNAEFHGRHMDCGGTLVPSGPGFENILPENQVCAFVGSRPGQSWVLGDDYLRAQYQYEYKNTWRNFGIMWCFLIGYIVLRAVFTEYKSPVKSGGDALVVKKGTKNAIQRSWSSKNDEENLNASIATQDMKEIASSNDDSTSADFEGLESTGVFIWKNVSFTIPHSSGQRKLLDSVSGYCVPGTLTALIGESGAGKTTLLNTLAQRNVGTITGDMLVDGLPMDASFKRRTGYVQQQDLHVAELTVKESLQFSARMRRPQSIPDAEKMEYVEKIISILEMQEFSEALVGEIGYGLNVEQRKKLSIGVELVGKPDLLLFLDEPTSGLDSQSAWAVVKMLKRLALAGQSILCTIHQPSATLFEQFDRLLLLGKGGQTIYFGEIGKNSSSVIKYFEKNGARKCQQNENPAEYILEAIGAGATASVQQNWPDIWQKSHEYANINEKINDMIKDLSSTTLHKTATRASKYATSYSYQFHHVLKRSSLTFWRNLNYIMAKMMLLMISGLFIGFTFFHVGVNAIGLQNSLFACFMAIVISAPATNQIQERATVAKELYEVRESKSNMFHWSLLLITHYLNELPYHLLFSTIFFVSSYFPLGVFTEASRSSVFYLNYAILFQLYYIGLALMILYMSPNLQSANVIVGFILSFLLSFCGAVQPASLMPGFWTFMWKLSPYTYFLQNLVGLLMHDKPVRCSKKELSLFNPPVGQTCGEFTKPFFEFGTGYIANPDATADCAYCQYKVGDEYLARINASFSYLWRNFGFI
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
48N-linked_GlycosylationKMKIILKNVSLLAKS
HHEEEEHHHHHHHHC		25.76-
144N-linked_GlycosylationMPAKRVNNVTKEEYI
CCCHHCCCCCHHHHH		39.72-
199PhosphorylationEALAAKGSIYCWDNA
HHHHHCCCEEEECCC		15.0727017623
201PhosphorylationLAAKGSIYCWDNATR
HHHCCCEEEECCCCC		6.8127017623
205N-linked_GlycosylationGSIYCWDNATRGLDS
CCEEEECCCCCCCCH		20.79-
207PhosphorylationIYCWDNATRGLDSST
EEEECCCCCCCCHHH		31.3727017623
238PhosphorylationTTALVTVYQASENIY
CHHHHEHHHCCCCHH		6.7628132839
245PhosphorylationYQASENIYETFDKVT
HHCCCCHHHHCCHHE		22.0928132839
349PhosphorylationTEWTKKTYNESMAQE
CHHHHHHHCHHHHCH		26.3027017623
350N-linked_GlycosylationEWTKKTYNESMAQEK
HHHHHHHCHHHHCHH		39.85-
352PhosphorylationTKKTYNESMAQEKSK
HHHHHCHHHHCHHCC		18.7727017623
697N-linked_GlycosylationKNDEENLNASIATQD
CCCHHHHCHHHHHHH		43.13-
733N-linked_GlycosylationTGVFIWKNVSFTIPH
CCEEEEEEEEEEECC		21.48-
949PhosphorylationLLGKGGQTIYFGEIG
CCCCCCCEEEEEECC		22.4027017623
951PhosphorylationGKGGQTIYFGEIGKN
CCCCCEEEEEECCCC		14.6627017623
958N-linked_GlycosylationYFGEIGKNSSSVIKY
EEEECCCCCHHHHHH		41.74-
1026PhosphorylationDMIKDLSSTTLHKTA
HHHHHHHHCHHHHHH		32.4819779198
1245PhosphorylationFMWKLSPYTYFLQNL
HHHHHCHHHHHHHHH		15.6528889911
1246PhosphorylationMWKLSPYTYFLQNLV
HHHHCHHHHHHHHHH		15.9228889911
1247PhosphorylationWKLSPYTYFLQNLVG
HHHCHHHHHHHHHHH		9.1028889911
1320N-linked_GlycosylationDEYLARINASFSYLW
HHHHHHHHHHHHHHH		24.79-
1324PhosphorylationARINASFSYLWRNFG
HHHHHHHHHHHHHCC		19.4728132839
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of PDR18_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of PDR18_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of PDR18_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
MKAR_YEASTIFA38physical
16093310
HSP71_YEASTSSA1physical
22940862
HSP72_YEASTSSA2physical
22940862
SSB1_YEASTSSB1physical
22940862
OSW5_YEASTOSW5physical
23831759
ZRC1_YEASTZRC1physical
23831759
ZRT1_YEASTZRT1genetic
23831759
PDR11_YEASTPDR11physical
23831759
DOA10_YEASTSSM4physical
23831759
TAF12_YEASTTAF12genetic
27708008
MOB2_YEASTMOB2genetic
27708008
SWC4_YEASTSWC4genetic
27708008
CDK1_YEASTCDC28genetic
27708008
APC11_YEASTAPC11genetic
27708008
CDC53_YEASTCDC53genetic
27708008
RPC10_YEASTRPC11genetic
27708008
MSS4_YEASTMSS4genetic
27708008
RPB7_YEASTRPB7genetic
27708008
ACT_YEASTACT1genetic
27708008
CDC12_YEASTCDC12genetic
27708008
PRI1_YEASTPRI1genetic
27708008
KTHY_YEASTCDC8genetic
27708008
MED4_YEASTMED4genetic
27708008
DYR_YEASTDFR1genetic
27708008
TBF1_YEASTTBF1genetic
27708008
TF2B_YEASTSUA7genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of PDR18_YEAST

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Related Literatures of Post-Translational Modification

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