ACPM_YEAST - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ACPM_YEAST
• UniProt AC: P32463
• Protein Name: Acyl carrier protein, mitochondrial
• Gene Name: ACP1
• Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
• Sequence Length: 125
• Subcellular Localization: Mitochondrion.
• Protein Description: Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity). May be involved in the synthesis of very-long-chain fatty acids. Accessory and non-catalytic subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain (By similarity)..
• Protein Sequence: MFRSVCRISSRVAPSAYRTIMGRSVMSNTILAQRFYSANLSKDQVSQRVIDVIKAFDKNSPNIANKQISSDTQFHKDLGLDSLDTVELLVAIEEEFDIEIPDKVADELRSVGETVDYIASNPDAN

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
24	Phosphorylation	YRTIMGRSVMSNTIL HHHHHCCHHHCCHHH	19.22	28889911
27	Phosphorylation	IMGRSVMSNTILAQR HHCCHHHCCHHHHHH	28.76	27017623
54	Acetylation	QRVIDVIKAFDKNSP HHHHHHHHHHCCCCC	42.73	24489116
58	Acetylation	DVIKAFDKNSPNIAN HHHHHHCCCCCCHHC	53.52	22865919
60	Phosphorylation	IKAFDKNSPNIANKQ HHHHCCCCCCHHCCC	25.68	21082442
66	Acetylation	NSPNIANKQISSDTQ CCCCHHCCCCCCCCH	39.73	24489116
66	2-Hydroxyisobutyrylation	NSPNIANKQISSDTQ CCCCHHCCCCCCCCH	39.73	-
69	Phosphorylation	NIANKQISSDTQFHK CHHCCCCCCCCHHHH	21.48	22369663
70	Phosphorylation	IANKQISSDTQFHKD HHCCCCCCCCHHHHH	46.43	22369663
72	Phosphorylation	NKQISSDTQFHKDLG CCCCCCCCHHHHHCC	34.77	22369663
82	O-(pantetheine 4'-phosphoryl)serine	HKDLGLDSLDTVELL HHHCCCCCCCHHHHH	32.94	-
82	Phosphorylation	HKDLGLDSLDTVELL HHHCCCCCCCHHHHH	32.94	-
110	Phosphorylation	KVADELRSVGETVDY HHHHHHHHHHCHHHH	47.28	28889911
120	Phosphorylation	ETVDYIASNPDAN-- CHHHHHHCCCCCC--	39.06	28889911

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ACPM_YEAST !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ACPM_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ACPM_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
UBP2_YEAST	UBP2	physical	18719252
MDHM_YEAST	MDH1	genetic	16941010
NDI1_YEAST	NDI1	genetic	16941010
OAC1_YEAST	OAC1	genetic	16941010
EFS_HUMAN	EFS	physical	27107014
F193B_HUMAN	FAM193B	physical	27107014

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.