dbPTM

NRK1_YEAST - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	NRK1_YEAST
UniProt AC	P53915
Protein Name	Nicotinamide riboside kinase
Gene Name	NRK1
Organism	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length	240
Subcellular Localization
Protein Description	Catalyzes the phosphorylation of nicotinamide riboside (NR) and nicotinic acid riboside (NaR) to form nicotinamide mononucleotide (NMN) and nicotinic acid mononucleotide (NaMN)..
Protein Sequence	MTSKKVILVALSGCSSSGKTTIAKLTASLFTKATLIHEDDFYKHDNEVPVDAKYNIQNWDSPEALDFKLFGKELDVIKQTGKIATKLIHNNNVDDPFTKFHIDRQVWDELKAKYDSINDDKYEVVIVDGFMIFNNTGISKKFDLKILVRAPYEVLKKRRASRKGYQTLDSFWVDPPYYFDEFVYESYRANHAQLFVNGDVEGLLDPRKSKNIKEFINDDDTPIAKPLSWVCQEILKLCKD

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
43	Acetylation	IHEDDFYKHDNEVPV ECCCCCCCCCCCCCC	44.46	24489116
72	Acetylation	LDFKLFGKELDVIKQ CCEEECCHHHHHHHH	48.01	24489116
99	Acetylation	NVDDPFTKFHIDRQV CCCCCCHHHHHCHHH	35.01	24489116

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of NRK1_YEAST !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of NRK1_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of NRK1_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
URH1_YEAST	URH1	genetic	17914902
PNPH_YEAST	PNP1	genetic	17914902
URH1_YEAST	URH1	genetic	19416965
PNPH_YEAST	PNP1	genetic	19416965
SIR2_YEAST	SIR2	genetic	19416965
DCOR_YEAST	SPE1	genetic	21623372
BIOD_YEAST	BIO4	genetic	21623372
ARO1_YEAST	ARO1	genetic	21623372
GPP2_YEAST	GPP2	genetic	21623372
FABD_YEAST	MCT1	genetic	21623372
COX9_YEAST	COX9	genetic	21623372
CEM1_YEAST	CEM1	genetic	21623372
THRC_YEAST	THR4	genetic	21623372
KAD2_YEAST	ADK1	genetic	21623372
ACON2_YEAST	ACO2	genetic	21623372
PDX3_YEAST	PDX3	genetic	21623372
AGX1_YEAST	AGX1	genetic	21623372
BLM10_YEAST	BLM10	genetic	27708008
MRM2_YEAST	MRM2	genetic	27708008
RL8B_YEAST	RPL8B	genetic	27708008
BMT6_YEAST	BMT6	genetic	27708008
SWC5_YEAST	SWC5	genetic	27708008
YCR3_YEAST	YCR023C	genetic	27708008
KIN82_YEAST	KIN82	genetic	27708008
RDS1_YEAST	RDS1	genetic	27708008
IES5_YEAST	IES5	genetic	27708008
YEV1_YEAST	YER121W	genetic	27708008
WWM1_YEAST	WWM1	genetic	27708008
ORM1_YEAST	ORM1	genetic	27708008
PEF1_YEAST	PEF1	genetic	27708008
YG37_YEAST	YGR127W	genetic	27708008
ENO1_YEAST	ENO1	genetic	27708008
HTD2_YEAST	HTD2	genetic	27708008
YIQ1_YEAST	YIL161W	genetic	27708008
MET28_YEAST	MET28	genetic	27708008
GZF3_YEAST	GZF3	genetic	27708008
SWE1_YEAST	SWE1	genetic	27708008
NNK1_YEAST	NNK1	genetic	27708008
NU133_YEAST	NUP133	genetic	27708008
RSSA2_YEAST	RPS0B	genetic	27708008
YL149_YEAST	YLR149C	genetic	27708008
YL152_YEAST	YLR152C	genetic	27708008
RFX1_YEAST	RFX1	genetic	27708008
LIPB_YEAST	LIP2	genetic	27708008
GLRX8_YEAST	GRX8	genetic	27708008
DUS3_YEAST	DUS3	genetic	27708008
YMK8_YEAST	YML108W	genetic	27708008
TMA23_YEAST	TMA23	genetic	27708008
MSN1_YEAST	MSN1	genetic	27708008
TRM11_YEAST	TRM11	genetic	27708008
KTR1_YEAST	KTR1	genetic	27708008
LIPA_YEAST	LIP5	genetic	27708008
FABD_YEAST	MCT1	genetic	27708008
RDL1_YEAST	RDL1	genetic	27708008

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of NRK1_YEAST

Related Literatures of Post-Translational Modification