dbPTM

ADRO_YEAST - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	ADRO_YEAST
UniProt AC	P48360
Protein Name	Probable NADPH:adrenodoxin oxidoreductase, mitochondrial
Gene Name	ARH1
Organism	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length	493
Subcellular Localization	Mitochondrion inner membrane Peripheral membrane protein .
Protein Description	Acts as an electron transfer protein. Essential for viability..
Protein Sequence	MSFVQIRHISSQINRKTVSIVGSGPSGFYTAYHLLKKSPIPLNVTIWEKLPVPFGLSRYGVAPDHPEVKNCEETFTTCAEEFSSPTNQKHKFSFVGGITIGKEILLKELLDNQDAVILSYGCTGDRKLNIPGELGTKGVFSSREFVNWYNGHPDFAKDKRFTDFDWSKVSKVGIIGNGNVALDITRVLISNQIDEIWENTDISSLALNLLRRAPVKDVKLIARRDFVHSKFTNKELRELWELEKYGIRGRIDPKFFQKEMFDPSKYDRAFNRRVEMCSEYLKPFNERSKKNYKKAPPPSSGYDKFWELDYLKTPLKINRDDFGAINSLSLCNNRLNEDNSLQPLKDVNNIMTYKVDLLITSLGYAGVPMPEFSKLSIGFDKDHIANKQGRVLTSSGEIFPHLYASGWIRKGSQGVIASTMQDAFEVGDRVIQDLVVSGALSLENSIDLSNIKHTTWKDWERINKKELLRGKKEHKTRSKFLTFEELWNGVEGI

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
230	Acetylation	RRDFVHSKFTNKELR ECCCCCCCCCCHHHH	41.13	24489116
265	Acetylation	KEMFDPSKYDRAFNR HHHCCHHHHHHHHHH	57.46	24489116
345	Acetylation	DNSLQPLKDVNNIMT CCCCCCCCCCCCHHH	67.33	24489116
381	Acetylation	KLSIGFDKDHIANKQ HHEECCCHHHHCCCC	49.28	24489116
445	Phosphorylation	GALSLENSIDLSNIK CCCCCCCCCCHHHCC	14.22	27017623

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of ADRO_YEAST !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of ADRO_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of ADRO_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
NOT1_YEAST	CDC39	physical	10688190
INA22_YEAST	INA22	physical	10688190
ERS1_YEAST	ERS1	genetic	27708008
XPO1_YEAST	CRM1	genetic	27708008
MED6_YEAST	MED6	genetic	27708008
DNA2_YEAST	DNA2	genetic	27708008
HACD_YEAST	PHS1	genetic	27708008
SEN1_YEAST	SEN1	genetic	27708008
BET5_YEAST	BET5	genetic	27708008
CH10_YEAST	HSP10	genetic	27708008
EI2BG_YEAST	GCD1	genetic	27708008
YAJ9_YEAST	YAR029W	genetic	27708008
H3_YEAST	HHT1	genetic	27708008
REI1_YEAST	REI1	genetic	27708008
PP2C1_YEAST	PTC1	genetic	27708008
VPS41_YEAST	VPS41	genetic	27708008
AIM11_YEAST	AIM11	genetic	27708008
SGF73_YEAST	SGF73	genetic	27708008
PSD2_YEAST	PSD2	genetic	27708008
MAL12_YEAST	MAL12	genetic	27708008
AIM17_YEAST	AIM17	genetic	27708008
INM1_YEAST	INM1	genetic	27708008
ICE2_YEAST	ICE2	genetic	27708008
FLX1_YEAST	FLX1	genetic	27708008
YJY1_YEAST	YJR011C	genetic	27708008
BFA1_YEAST	BFA1	genetic	27708008
POM33_YEAST	POM33	genetic	27708008
STB4_YEAST	STB4	genetic	27708008
CBPY_YEAST	PRC1	genetic	27708008
PMS1_YEAST	PMS1	genetic	27708008
NOP12_YEAST	NOP12	genetic	27708008
LDS2_YEAST	LDS2	genetic	27708008
CY1_YEAST	CYT1	genetic	27708008
WHI5_YEAST	WHI5	genetic	27708008
RS10A_YEAST	RPS10A	genetic	27708008
MUM3_YEAST	MUM3	genetic	27708008
RAD1_YEAST	RAD1	genetic	27708008
GGPPS_YEAST	BTS1	genetic	27708008
NEW1_YEAST	NEW1	genetic	27708008
FUMH_YEAST	FUM1	genetic	27708008
YP022_YEAST	YPR022C	genetic	27708008
CTF4_YEAST	CTF4	genetic	27708008

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of ADRO_YEAST

Related Literatures of Post-Translational Modification