YCB2_YEAST - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: YCB2_YEAST
• UniProt AC: Q8J0M4
• Protein Name: UPF0357 protein YCL012C
• Gene Name: YCL012C
• Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
• Sequence Length: 134
• Protein Sequence: MKSLFYLKLLLWVVLLSLCLLMAHRKTKVADKFRALRSRIQLRFNRHIRLNDSFADDLENGLHSRNFDIISENSNDVRGGLDDVSKNEIKQIMENDNVDFDKARLLYMERKFGQNGIAPDGTPIDPKAFTFDSR

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
53	Phosphorylation	RHIRLNDSFADDLEN CCCCCCCCHHHHHHC	22.66	28889911
64	Phosphorylation	DLENGLHSRNFDIIS HHHCCCHHCCCEEEC	33.68	23749301
71	Phosphorylation	SRNFDIISENSNDVR HCCCEEECCCCCCCC	30.93	22369663
74	Phosphorylation	FDIISENSNDVRGGL CEEECCCCCCCCCCC	30.29	22369663
86	Ubiquitination	GGLDDVSKNEIKQIM CCCCCCCHHHHHHHH	59.45	23749301
90	Ubiquitination	DVSKNEIKQIMENDN CCCHHHHHHHHHCCC	27.82	23749301
102	Ubiquitination	NDNVDFDKARLLYME CCCCCHHHHHHHHHH	35.09	23749301
111	Ubiquitination	RLLYMERKFGQNGIA HHHHHHHHHCCCCCC	40.31	23749301
122	Phosphorylation	NGIAPDGTPIDPKAF CCCCCCCCCCCCCCC	25.17	23749301
127	Ubiquitination	DGTPIDPKAFTFDSR CCCCCCCCCCCCCCC	53.00	23749301
133	Phosphorylation	PKAFTFDSR------ CCCCCCCCC------	35.38	21440633

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of YCB2_YEAST !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of YCB2_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of YCB2_YEAST !!

Protein-Protein Interaction

Oops, there are no PPI records of YCB2_YEAST !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"A multidimensional chromatography technology for in-depthphosphoproteome analysis.";
Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.;
Mol. Cell. Proteomics 7:1389-1396(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-71; SER-74 AND SER-133,AND MASS SPECTROMETRY.
PubMed: 18407956