COS5_YEAST - dbPTM
COS5_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID COS5_YEAST
UniProt AC P47187
Protein Name Protein COS5
Gene Name COS5
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 383
Subcellular Localization Membrane
Multi-pass membrane protein.
Protein Description
Protein Sequence MKENELKNEKSVDVLSFKQLESQKIVLPQDLFRSSFTWFCYEIYKSLAFPIWMLLWLPLSVWWKLSNNCIYPLIVSLLVLFLGPIFVLVICGLSRKRSLSKQLIQFCKEVTENTPSSDPHDWEVVAANLNSYLYENKAWNTRYFFFNAMGCQEAFRTTLLEPFSLKKDEAAKVKSFKDSVPYIEEALGVYFREVEKQWKLFNTEKSWSPVGLEDVQLPKDIHRSKLTWFLKRIFTIYSLPLWLAFLNCICVSQHFCLAFRILCPGLFFLMMVWLFQNMRTTALLVKMEHKMQFLLTIINEQESGANGWDEIARKMNRYLFEKKAWKNEEFFFEGIDCEWFFSHFFYRLLSAKKSMWLLPLNVELWPYIKEAQLSRNEESLMKK
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
7Ubiquitination-MKENELKNEKSVDV
-CCHHHCCCCCCCCE		57.8124961812
10UbiquitinationENELKNEKSVDVLSF
HHHCCCCCCCCEEEH		66.2423749301
11PhosphorylationNELKNEKSVDVLSFK
HHCCCCCCCCEEEHH		19.8522890988
16PhosphorylationEKSVDVLSFKQLESQ
CCCCCEEEHHHHHHC		30.1922369663
18UbiquitinationSVDVLSFKQLESQKI
CCCEEEHHHHHHCCE		51.0723749301
203PhosphorylationKQWKLFNTEKSWSPV
HHHHHHCCCCCCCCC		37.1428889911
205UbiquitinationWKLFNTEKSWSPVGL
HHHHCCCCCCCCCCH		56.0123793018
382UbiquitinationRNEESLMKK------
CCHHHHHCC------		61.7023749301
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of COS5_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of COS5_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of COS5_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
MKAR_YEASTIFA38physical
16093310
ELO2_YEASTELO2physical
16093310
HXT9_YEASTHXT9physical
16093310
RSP5_YEASTRSP5physical
25942624
CND2_YEASTBRN1genetic
27708008
SEC65_YEASTSEC65genetic
27708008
OST2_YEASTOST2genetic
27708008
TF2B_YEASTSUA7genetic
27708008
SIF2_YEASTSIF2genetic
27708008
COQ11_YEASTYLR290Cgenetic
27708008
MKS1_YEASTMKS1genetic
27708008
EOS1_YEASTEOS1genetic
27708008
CDK1_YEASTCDC28genetic
27708008
CDC10_YEASTCDC10genetic
27708008
TFB1_YEASTTFB1genetic
27708008
RPB7_YEASTRPB7genetic
27708008
COG3_YEASTCOG3genetic
27708008
CDC4_YEASTCDC4genetic
27708008
SMD1_YEASTSMD1genetic
27708008
CDC12_YEASTCDC12genetic
27708008
SEC6_YEASTSEC6genetic
27708008
PRP19_YEASTPRP19genetic
27708008
CDC3_YEASTCDC3genetic
27708008
ORC1_YEASTORC1genetic
27708008
POB3_YEASTPOB3genetic
27708008
UTP15_YEASTUTP15genetic
27708008
HRR25_YEASTHRR25genetic
27708008
BUR1_YEASTSGV1genetic
27708008
RL4A_YEASTRPL4Agenetic
27708008
RXT2_YEASTRXT2genetic
27708008
GID4_YEASTVID24genetic
27708008
CCZ1_YEASTCCZ1genetic
27708008
RS6A_YEASTRPS6Bgenetic
27708008
RS6B_YEASTRPS6Bgenetic
27708008
SWC5_YEASTSWC5genetic
27708008
YCY0_YEASTYCR090Cgenetic
27708008
GPR1_YEASTGPR1genetic
27708008
TPS2_YEASTTPS2genetic
27708008
VPS41_YEASTVPS41genetic
27708008
RAD9_YEASTRAD9genetic
27708008
MSH4_YEASTMSH4genetic
27708008
IES1_YEASTIES1genetic
27708008
PIB2_YEASTPIB2genetic
27708008
PALF_YEASTRIM8genetic
27708008
ASK10_YEASTASK10genetic
27708008
RL8A_YEASTRPL8Agenetic
27708008
YIF5_YEASTYIL055Cgenetic
27708008
ATG32_YEASTATG32genetic
27708008
PHO86_YEASTPHO86genetic
27708008
YJQ3_YEASTYJL163Cgenetic
27708008
YJY1_YEASTYJR011Cgenetic
27708008
IRS4_YEASTIRS4genetic
27708008
CSF1_YEASTCSF1genetic
27708008
ACE2_YEASTACE2genetic
27708008
YL149_YEASTYLR149Cgenetic
27708008
EFM7_YEASTNNT1genetic
27708008
AMPD_YEASTAMD1genetic
27708008
GTR1_YEASTGTR1genetic
27708008
SOK2_YEASTSOK2genetic
27708008
RAD14_YEASTRAD14genetic
27708008
YHM2_YEASTYHM2genetic
27708008
SPO1_YEASTSPO1genetic
27708008
SIW14_YEASTSIW14genetic
27708008
RHO2_YEASTRHO2genetic
27708008
WHI5_YEASTWHI5genetic
27708008
KIN4_YEASTKIN4genetic
27708008
TBP6_YEASTYTA6genetic
27708008
ACEB_YEASTICL2genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of COS5_YEAST

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Related Literatures of Post-Translational Modification

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