MAG2_YEAST - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: MAG2_YEAST
• UniProt AC: Q06436
• Protein Name: RING-finger protein MAG2
• Gene Name: MAG2
• Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
• Sequence Length: 670
• Subcellular Localization: Cytoplasm .
• Protein Sequence: MVEPDMQKKASGGSGGSEMDTLNATSNSSKQGVSNNKRNPVSKKKPGNKVSDGRDNAHNYHGEGRRKSSKQQRSRTPYKETSTRINDQDIDLSIQEEILGGNFKLRGRKTQVSINHLLNFQLPEVEREKSRSSSSKKSNRRRDEHVHLHGDTFVNVNYRLLVDDRFDYPEQNCNPNVPVDQEKILRVIVPKGQNCSICLSEEPVAPRMVTCGHIFCLSCLLNFFSIEETVKNKETGYSKKKKYKECPLCGSIIGPKRVKPVLYEDDFDVTRLNQKPEPGATVHLQLMCKPHGSLLPLPVALHLDPLKCGNFPPANLGSIKHYAHIMKCGVSYSLELYQKDIVAIQEQYEIDKAIYNDSGKFVKQSIENINDQISTLLAATTDLSPLSNDINNGLDNFHFDDDLLTKYDDSSAYFFYQTLVASSTKYFLSPLDVKILLTIFHYYSKFPESIETTVENIHYDTVVTEQLIRRYKYIGHLPIGTEIALLDLDWRKIPFLPKEIYEQFAHELKQRRRKFTMKKQKEDKEKKLYEKRLEQEHAEFYRKENGNSLKFEDSVQMATHYESIVSSSIPLNSLGISMLGPPTNSCSTPQKQAPSHTKRTIWGTSIAVTEDEKASKENKEFQDMLLQRIRQEDSSDVTDSTDSPPTSNGKRGRKKKGKVMLFSSNHQALG

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
8	Ubiquitination	MVEPDMQKKASGGSG CCCHHHCCCCCCCCC	43.60	22817900
9	Ubiquitination	VEPDMQKKASGGSGG CCHHHCCCCCCCCCC	30.78	23749301
14	Phosphorylation	QKKASGGSGGSEMDT CCCCCCCCCCCCHHH	43.43	28889911
17	Phosphorylation	ASGGSGGSEMDTLNA CCCCCCCCCHHHCCC	33.02	27017623
28	Phosphorylation	TLNATSNSSKQGVSN HCCCCCCCCCCCCCC	38.38	27017623
30	Ubiquitination	NATSNSSKQGVSNNK CCCCCCCCCCCCCCC	51.39	23749301
49	Ubiquitination	SKKKPGNKVSDGRDN CCCCCCCCCCCCCCC	49.37	17644757
79	Ubiquitination	QRSRTPYKETSTRIN HHCCCCCCHHCCCCC	56.57	17644757
104	Ubiquitination	EILGGNFKLRGRKTQ HHHCCCCEECCCCCE	41.07	17644757
109	Ubiquitination	NFKLRGRKTQVSINH CCEECCCCCEEEHHH	46.24	17644757
129	Ubiquitination	LPEVEREKSRSSSSK CCHHHHHHHCCCCCC	58.34	17644757
183	Ubiquitination	NVPVDQEKILRVIVP CCCCCHHHEEEEEEE	41.21	17644757
191	Ubiquitination	ILRVIVPKGQNCSIC EEEEEEECCCCCEEE	63.33	23749301
210	Phosphorylation	PVAPRMVTCGHIFCL CCCCCEEHHHHHHHH	11.92	21440633
242	Ubiquitination	TGYSKKKKYKECPLC CCCCCCCCCCCCCCC	71.13	17644757
243	Phosphorylation	GYSKKKKYKECPLCG CCCCCCCCCCCCCCC	22.39	27017623
244	Ubiquitination	YSKKKKYKECPLCGS CCCCCCCCCCCCCCC	62.82	17644757
256	Ubiquitination	CGSIIGPKRVKPVLY CCCCCCCCCCCCCEE	65.69	17644757
259	Ubiquitination	IIGPKRVKPVLYEDD CCCCCCCCCCEEECC	33.18	17644757
337	Phosphorylation	VSYSLELYQKDIVAI CEEEEEEHHHCEEEE	12.25	19779198
425	Ubiquitination	TLVASSTKYFLSPLD HHHHHCCCCCCCHHH	35.63	17644757
434	Ubiquitination	FLSPLDVKILLTIFH CCCHHHHHHHHHHHH	27.57	17644757
472	Ubiquitination	EQLIRRYKYIGHLPI HHHHHHHCCCCCCCC	28.69	17644757
492	Ubiquitination	LLDLDWRKIPFLPKE EEECCHHCCCCCCHH	50.94	17644757
498	Ubiquitination	RKIPFLPKEIYEQFA HCCCCCCHHHHHHHH	59.91	17644757
509	Acetylation	EQFAHELKQRRRKFT HHHHHHHHHHHHHHH	38.48	24489116
509	Ubiquitination	EQFAHELKQRRRKFT HHHHHHHHHHHHHHH	38.48	17644757
531	Ubiquitination	KEKKLYEKRLEQEHA HHHHHHHHHHHHHHH	49.04	17644757
543	Ubiquitination	EHAEFYRKENGNSLK HHHHHHHHHCCCCCC	44.12	17644757
613	Ubiquitination	IAVTEDEKASKENKE EEECCCHHHHHHCHH	70.99	15699485
616	Ubiquitination	TEDEKASKENKEFQD CCCHHHHHHCHHHHH	70.89	15699485
619	Ubiquitination	EKASKENKEFQDMLL HHHHHHCHHHHHHHH	62.08	24961812
634	Phosphorylation	QRIRQEDSSDVTDST HHHHHHCCCCCCCCC	27.90	23749301
635	Phosphorylation	RIRQEDSSDVTDSTD HHHHHCCCCCCCCCC	48.71	28889911
650	Ubiquitination	SPPTSNGKRGRKKKG CCCCCCCCCCCCCCC	56.80	17644757

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of MAG2_YEAST !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of MAG2_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of MAG2_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
AIM46_YEAST	AIM46	physical	11805837
HAS1_YEAST	HAS1	physical	11805837
IF4F2_YEAST	TIF4632	physical	11805837
UTP22_YEAST	UTP22	physical	11805837
FET4_YEAST	FET4	physical	11805837
MG101_YEAST	MGM101	physical	11805837
NOP12_YEAST	NOP12	physical	11805837
OYE2_YEAST	OYE2	physical	11805837
RPF2_YEAST	RPF2	physical	11805837
IF2P_YEAST	FUN12	physical	11805837
ARE1_YEAST	ARE1	physical	11805837
IF4F1_YEAST	TIF4631	physical	11805837
NOP3_YEAST	NPL3	physical	11805837
IF4E_YEAST	CDC33	physical	11805837
IMDH3_YEAST	IMD3	physical	11805837
NOC2_YEAST	NOC2	physical	11805837
SYG_YEAST	GRS1	physical	11805837
IMDH2_YEAST	IMD2	physical	11805837
MSC3_YEAST	MSC3	physical	11805837
NOP4_YEAST	NOP4	physical	11805837
IMDH4_YEAST	IMD4	physical	11805837
NAT10_YEAST	KRE33	physical	11805837
RRP12_YEAST	RRP12	physical	11805837
PDC6_YEAST	PDC6	physical	11805837
KRI1_YEAST	KRI1	physical	11805837
GNA1_YEAST	GNA1	genetic	27708008
MOB2_YEAST	MOB2	genetic	27708008
GPI10_YEAST	GPI10	genetic	27708008
GPI18_YEAST	GPI18	genetic	27708008
KRR1_YEAST	KRR1	genetic	27708008
PRP9_YEAST	PRP9	genetic	27708008
TIM22_YEAST	TIM22	genetic	27708008
CDC13_YEAST	CDC13	genetic	27708008
TRS23_YEAST	TRS23	genetic	27708008
COG3_YEAST	COG3	genetic	27708008
TAF6_YEAST	TAF6	genetic	27708008
YIP1_YEAST	YIP1	genetic	27708008
ZPR1_YEAST	ZPR1	genetic	27708008
YHS2_YEAST	CIA2	genetic	27708008
TIM16_YEAST	PAM16	genetic	27708008
XRN2_YEAST	RAT1	genetic	27708008
PSA7_YEAST	PRE10	genetic	27708008
TF2B_YEAST	SUA7	genetic	27708008
PSB5_YEAST	PRE2	genetic	27708008
RPN7_YEAST	RPN7	genetic	27708008
PGTB2_YEAST	BET2	genetic	27708008

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.