| UniProt ID | ETFD_YEAST | |
|---|---|---|
| UniProt AC | Q08822 | |
| Protein Name | Probable electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | |
| Gene Name | CIR2 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 631 | |
| Subcellular Localization | Mitochondrion inner membrane . | |
| Protein Description | Accepts electrons from ETF and reduces ubiquinone.. | |
| Protein Sequence | MIKFTNENLIRGIRMTISAKSRHLALGTDMTRKFSLSCRFLNKANLTEEEKELLNEPRARDYVDVCIVGGGPAGLATAIKLKQLDNSSGTGQLRVVVLEKSSVLGGQTVSGAILEPGVWKELFPDEKSDIGIPLPKELATLVTKEHLKFLKGKWAISVPEPSQMINKGRNYIVSLNQVVGYLGEKAEEVGVEVYPGIAVSDLIYDENNAVKGVITKDAGISKSGKPKETFERGMEFWARQTVLAEGCHGSLTKQALAKYDLRKGRQHQTYGLGIKEVWEVKPENFNKGFAAHTMGYPLTNDVYGGGFQYHFGDGLVTVGLVVGLDYKNPYVSPYKEFQKMKHHPYYSKVLEGGKCIAYAARALNEGGLQSVPKLNFPGGVLVGASAGFMNVPKIKGTHTAMKSGLLAAESIFESIKGLPVLEEVEDEDAKMAMFDKEATINLESYESAFKESSIYKELYEVRNIRPSFSGKLGGYGGMIYSGIDSLILKGKVPWTLKFDEKNDGEILEPASKYKPIEYPKPDGVISFDILTSVSRTGTYHDDDEPCHLRVPGQDMVKYAERSFPVWKGVESRFCPAGVYEFVKDEKSPVGTRLQINSQNCIHCKTCDIKAPRQDITWKVPEGGDGPKYTLT | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 3 | Ubiquitination | -----MIKFTNENLI -----CCCCCCHHHH | 44.85 | 23793018 | |
| 51 | Acetylation | ANLTEEEKELLNEPR CCCCHHHHHHHCCCC | 57.87 | 24489116 | |
| 127 | Acetylation | KELFPDEKSDIGIPL HHHCCCCCCCCCCCC | 61.89 | 24489116 | |
| 136 | Acetylation | DIGIPLPKELATLVT CCCCCCCHHHHHHHC | 73.39 | 24489116 | |
| 144 | Acetylation | ELATLVTKEHLKFLK HHHHHHCHHHHHHHC | 35.34 | 24489116 | |
| 221 | Phosphorylation | ITKDAGISKSGKPKE EECCCCCCCCCCCHH | 21.61 | 27017623 | |
| 223 | Phosphorylation | KDAGISKSGKPKETF CCCCCCCCCCCHHHH | 45.30 | 27017623 | |
| 335 | Acetylation | NPYVSPYKEFQKMKH CCCCCCCHHHHHCCC | 56.27 | 24489116 | |
| 370 | Phosphorylation | LNEGGLQSVPKLNFP HHCCCCCCCCCCCCC | 45.49 | 22369663 | |
| 456 | Acetylation | FKESSIYKELYEVRN HHHCHHHHHHHHHHC | 39.30 | 24489116 | |
| 467 | Phosphorylation | EVRNIRPSFSGKLGG HHHCCCCCCCCCCCC | 23.38 | 23749301 | |
| 469 | Phosphorylation | RNIRPSFSGKLGGYG HCCCCCCCCCCCCCC | 39.08 | 23749301 | |
| 471 | Ubiquitination | IRPSFSGKLGGYGGM CCCCCCCCCCCCCCE | 42.64 | 23749301 | |
| 481 | Phosphorylation | GYGGMIYSGIDSLIL CCCCEEEECCCEEEE | 20.53 | 23749301 | |
| 501 | Acetylation | WTLKFDEKNDGEILE CEEEECCCCCCCCCC | 63.28 | 24489116 | |
| 557 | Acetylation | VPGQDMVKYAERSFP CCCHHHHHHHHHHCC | 31.91 | 24489116 | |
| 586 | Acetylation | YEFVKDEKSPVGTRL CHHHCCCCCCCCCEE | 70.91 | 24489116 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of ETFD_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of ETFD_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of ETFD_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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