ERV2_YEAST - dbPTM
ERV2_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID ERV2_YEAST
UniProt AC Q12284
Protein Name FAD-linked sulfhydryl oxidase ERV2
Gene Name ERV2
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 196
Subcellular Localization Endoplasmic reticulum membrane
Single-pass type III membrane protein
Lumenal side .
Protein Description FAD-dependent sulfhydryl oxidase that catalyzes disulfide bond formation in the endoplasmic reticulum lumen in parallel to ERO1..
Protein Sequence MKQIVKRSHAIRIVAALGIIGLWMFFSSNELSIATPGLIKAKSGIDEVQGAAAEKNDARLKEIEKQTIMPLMGDDKVKKEVGRASWKYFHTLLARFPDEPTPEEREKLHTFIGLYAELYPCGECSYHFVKLIEKYPVQTSSRTAAAMWGCHIHNKVNEYLKKDIYDCATILEDYDCGCSDSDGKRVSLEKEAKQHG
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
42UbiquitinationTPGLIKAKSGIDEVQ
CHHHHHHHCCCCHHH		44.1823749301
43PhosphorylationPGLIKAKSGIDEVQG
HHHHHHHCCCCHHHH		45.9321126336
55UbiquitinationVQGAAAEKNDARLKE
HHHHHHHHCHHHHHH		56.2423749301
55AcetylationVQGAAAEKNDARLKE
HHHHHHHHCHHHHHH		56.2424489116
134AcetylationHFVKLIEKYPVQTSS
HHHHHHHHCCCCCCC		48.1124489116
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of ERV2_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of ERV2_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of ERV2_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
ERV2_YEASTERV2physical
11740506
SEC62_YEASTSEC62physical
18719252
NTM1_YEASTTAE1genetic
27708008
GPR1_YEASTGPR1genetic
27708008
SAC3_YEASTSAC3genetic
27708008
CYPD_YEASTCPR5genetic
27708008
RAD4_YEASTRAD4genetic
27708008
MMS2_YEASTMMS2genetic
27708008
ASK10_YEASTASK10genetic
27708008
CHO2_YEASTCHO2genetic
27708008
ETP1_YEASTETP1genetic
27708008
OCA5_YEASTOCA5genetic
27708008
MET5_YEASTMET5genetic
27708008
YRA2_YEASTYRA2genetic
27708008
PML1_YEASTPML1genetic
27708008
RL37A_YEASTRPL37Agenetic
27708008
EIF3J_YEASTHCR1genetic
27708008
ENT2_YEASTENT2genetic
27708008
COA4_YEASTCOA4genetic
27708008
VAM3_YEASTVAM3genetic
27708008
RS10A_YEASTRPS10Agenetic
27708008
SFG1_YEASTSFG1genetic
27708008
MDL2_YEASTMDL2genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of ERV2_YEAST

loading...

Related Literatures of Post-Translational Modification

TOP
© 2024 Institute of Bioinformatics and Systems Biology, NYCU | Designed by : BiOmics Laboratory