dbPTM

FYV7_YEAST - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	FYV7_YEAST
UniProt AC	Q12247
Protein Name	rRNA-processing protein FYV7
Gene Name	FYV7
Organism	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length	151
Subcellular Localization	Nucleus, nucleolus .
Protein Description	Involved in the processing of the 20S pre-rRNA. Required for survival upon K1 Killer toxin exposure..
Protein Sequence	MGTAKQNQNRKKFTREYKVKEIQRSITKKTRLRKEYLKALKDEGYAVPEKEPKTVAKESVRKIKEARAIEGKKKLDEKKEIKKQRKRMQKDELNKQRNEQLERIRVSKEKFQRREDRKKKLTQRTRTGQPLMGPKIEDLLDKIKTDDTYTS

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
36	Phosphorylation	KTRLRKEYLKALKDE HHHHHHHHHHHHHHC	19.28	27017623
41	Acetylation	KEYLKALKDEGYAVP HHHHHHHHHCCCCCC	59.60	25381059
90	Acetylation	KQRKRMQKDELNKQR HHHHHHHHHHHHHHH	43.77	25381059
142	Acetylation	KIEDLLDKIKTDDTY HHHHHHHHHHCCCCC	46.18	22865919
145	Phosphorylation	DLLDKIKTDDTYTS- HHHHHHHCCCCCCC-	42.45	19779198
148	Phosphorylation	DKIKTDDTYTS---- HHHHCCCCCCC----	31.35	27717283
149	Phosphorylation	KIKTDDTYTS----- HHHCCCCCCC-----	16.39	19779198

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of FYV7_YEAST !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of FYV7_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of FYV7_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
CHK1_YEAST	CHK1	genetic	20093466
NOP6_YEAST	NOP6	genetic	20093466
YG34_YEAST	YGR122W	genetic	20093466
RL1D1_YEAST	UTP30	genetic	20093466
HBS1_YEAST	HBS1	genetic	20093466
EAF7_YEAST	EAF7	genetic	20093466
BRE5_YEAST	BRE5	genetic	20093466
BUD21_YEAST	BUD21	genetic	20093466
WHI5_YEAST	WHI5	genetic	20093466
MBF1_YEAST	MBF1	genetic	20093466
SUR1_YEAST	SUR1	genetic	20093466
CHK1_YEAST	CHK1	genetic	22282571
MAK16_YEAST	MAK16	genetic	27708008
PRS8_YEAST	RPT6	genetic	27708008
NOP2_YEAST	NOP2	genetic	27708008
IF6_YEAST	TIF6	genetic	27708008
APC11_YEAST	APC11	genetic	27708008
FBRL_YEAST	NOP1	genetic	27708008
NOP14_YEAST	NOP14	genetic	27708008
RS13_YEAST	RPS13	genetic	27708008
ERF3_YEAST	SUP35	genetic	27708008
CDC1_YEAST	CDC1	genetic	27708008
FCF1_YEAST	FCF1	genetic	27708008
UTP5_YEAST	UTP5	genetic	27708008
UTP6_YEAST	UTP6	genetic	27708008
RMRP_YEAST	SNM1	genetic	27708008
RRP3_YEAST	RRP3	genetic	27708008
UTP9_YEAST	UTP9	genetic	27708008
NUP85_YEAST	NUP85	genetic	27708008
DBP9_YEAST	DBP9	genetic	27708008
UTP15_YEAST	UTP15	genetic	27708008
MED11_YEAST	MED11	genetic	27708008
RRP5_YEAST	RRP5	genetic	27708008
HAS1_YEAST	HAS1	genetic	27708008
NAT10_YEAST	KRE33	genetic	27708008
NUF2_YEAST	NUF2	genetic	27708008
IPL1_YEAST	IPL1	genetic	27708008
DIM1_YEAST	DIM1	genetic	27708008
YBQ6_YEAST	YBR056W	genetic	27708008
SWC5_YEAST	SWC5	genetic	27708008
CHK1_YEAST	CHK1	genetic	27708008
NOP6_YEAST	NOP6	genetic	27708008
SWR1_YEAST	SWR1	genetic	27708008
RL1D1_YEAST	UTP30	genetic	27708008
HBS1_YEAST	HBS1	genetic	27708008
EAF7_YEAST	EAF7	genetic	27708008
YNO0_YEAST	YNL140C	genetic	27708008
BRE5_YEAST	BRE5	genetic	27708008
BUD21_YEAST	BUD21	genetic	27708008
WHI5_YEAST	WHI5	genetic	27708008
SUR1_YEAST	SUR1	genetic	27708008

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of FYV7_YEAST

Related Literatures of Post-Translational Modification