RAD28_YEAST - dbPTM
RAD28_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID RAD28_YEAST
UniProt AC Q12021
Protein Name Radiation-sensitive protein 28
Gene Name RAD28
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 506
Subcellular Localization Nucleus .
Protein Description Involved in transcription-coupled repair nucleotide excision repair (NER) of UV-induced DNA lesions..
Protein Sequence MDPFLEFRVGNISLNEFYRRTIQSEFERILEDPLSNMKNYRFSKQSNYSTKEKTPLSIGVNCLDIDDTGQVLLGGGDDGSLSIWGLDESLHRNDEGEQELINKRLNYIKRQPHQSDDEPAQIMGYKNKRTRINDNNTMRLVHSFQTQRNKYRMYRQSSAAVPVQRSHISNKTDSPIGFSETLSETDSEASISHHKYGITTLKWYKADNGMFFTGSNDKTVKIWDTNRFEAVQDINLGYKINQIDNNVVDDSSLLVVASEDYYPRLIDLRTMNSGVTALGMGNQTRMQSEILCCKFNPVREQIIACGDMEGGVKLWDLRMRNRLYSELKRNKNRFKTINNDDNDDQSDVYFSSNQSKAHLRCCSDIVWNSEGSELCSVGMDGKLNVWRPFTEILQPEGLASYSQLGTQDLSRIKYKKRVSRRLLWFDKFLLCITDNGEVEIYNTEEKKLWNKLEYPMVNQVKKNQASHCQFSSMIVQTNIMNSVGLKLFFGTNNNTVSDGGSIFECS
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
251PhosphorylationDNNVVDDSSLLVVAS
CCCCCCCCCEEEEEC
20.5827017623
252PhosphorylationNNVVDDSSLLVVASE
CCCCCCCCEEEEECC
32.4927017623
258PhosphorylationSSLLVVASEDYYPRL
CCEEEEECCCCCCCE
21.2827017623

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of RAD28_YEAST !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of RAD28_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of RAD28_YEAST !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
TCPB_YEASTCCT2physical
11805837
TCPA_YEASTTCP1physical
11805837
TCPZ_YEASTCCT6physical
11805837
DUN1_YEASTDUN1physical
11805837
NHP10_YEASTNHP10genetic
17314980
MTU1_YEASTSLM3genetic
17314980
SEC23_YEASTSEC23genetic
27708008
CDC37_YEASTCDC37genetic
27708008
TFB1_YEASTTFB1genetic
27708008
GNA1_YEASTGNA1genetic
27708008
MOB2_YEASTMOB2genetic
27708008
GPI10_YEASTGPI10genetic
27708008
ORC1_YEASTORC1genetic
27708008
NOP2_YEASTNOP2genetic
27708008
NAT10_YEASTKRE33genetic
27708008
APC5_YEASTAPC5genetic
27708008
RPN7_YEASTRPN7genetic
27708008
BUR1_YEASTSGV1genetic
27708008

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of RAD28_YEAST

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Related Literatures of Post-Translational Modification

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