dbPTM

TMA7_YEAST - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	TMA7_YEAST
UniProt AC	Q3E764
Protein Name	Translation machinery-associated protein 7
Gene Name	TMA7
Organism	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length	64
Subcellular Localization	Cytoplasm . Nucleus .
Protein Description	Involved in protein synthesis..
Protein Sequence	MSSRQGGKMKPLKQKKKQQQDLDPEDIAFKEKQKADAAAKKALMANMKSGKPLVGGGIKKSGKK

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
8	Acetylation	MSSRQGGKMKPLKQK CCCCCCCCCCCHHHH	51.04	25381059
10	Acetylation	SRQGGKMKPLKQKKK CCCCCCCCCHHHHHH	51.16	25381059
16	Acetylation	MKPLKQKKKQQQDLD CCCHHHHHHHHCCCC	54.01	24489116
17	Ubiquitination	KPLKQKKKQQQDLDP CCHHHHHHHHCCCCH	61.45	23749301
30	Ubiquitination	DPEDIAFKEKQKADA CHHHHHHHHHHHHHH	55.79	23749301
30	Acetylation	DPEDIAFKEKQKADA CHHHHHHHHHHHHHH	55.79	24489116
32	Acetylation	EDIAFKEKQKADAAA HHHHHHHHHHHHHHH	58.66	24489116
41	Acetylation	KADAAAKKALMANMK HHHHHHHHHHHHHCC	41.86	25381059
48	Ubiquitination	KALMANMKSGKPLVG HHHHHHCCCCCCCCC	56.73	22817900
48	Acetylation	KALMANMKSGKPLVG HHHHHHCCCCCCCCC	56.73	25381059
49	Phosphorylation	ALMANMKSGKPLVGG HHHHHCCCCCCCCCC	41.08	21440633
51	Ubiquitination	MANMKSGKPLVGGGI HHHCCCCCCCCCCCC	42.12	23749301
59	Acetylation	PLVGGGIKKSGKK-- CCCCCCCCCCCCC--	44.13	25381059

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of TMA7_YEAST !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of TMA7_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of TMA7_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
YG1O_YEAST	YGR035C	genetic	20093466
YOR1_YEAST	YOR1	genetic	20093466
SDHX_YEAST	YJL045W	genetic	20093466
YJ24_YEAST	KCH1	genetic	20093466
YP257_YEAST	YPL257W	genetic	20093466
YP191_YEAST	YPL191C	genetic	20093466
PMA2_YEAST	PMA2	genetic	20093466
YP078_YEAST	YPR078C	genetic	20093466
YBB0_YEAST	YBL010C	genetic	27708008
MRM2_YEAST	MRM2	genetic	27708008
PIL1_YEAST	PIL1	genetic	27708008
DAP2_YEAST	DAP2	genetic	27708008
SDHX_YEAST	YJL045W	genetic	27708008
YJ24_YEAST	KCH1	genetic	27708008
RL8B_YEAST	RPL8B	genetic	27708008
VPS9_YEAST	VPS9	genetic	27708008
PEX12_YEAST	PEX12	genetic	27708008
SWS2_YEAST	SWS2	genetic	27708008
FAR11_YEAST	FAR11	genetic	27708008
YP257_YEAST	YPL257W	genetic	27708008
YP078_YEAST	YPR078C	genetic	27708008
BUD3_YEAST	BUD3	genetic	29674565
AK_YEAST	HOM3	genetic	29674565
LST8_YEAST	LST8	genetic	29674565
AIM4_YEAST	AIM4	genetic	29674565
SPT3_YEAST	SPT3	genetic	29674565
ITR1_YEAST	ITR1	genetic	29674565
COG3_YEAST	COG3	genetic	29674565
PUF4_YEAST	PUF4	genetic	29674565
APQ12_YEAST	APQ12	genetic	29674565
MTC1_YEAST	MTC1	genetic	29674565
VPS35_YEAST	VPS35	genetic	29674565
ENT3_YEAST	ENT3	genetic	29674565
KTI12_YEAST	KTI12	genetic	29674565
APC2_YEAST	APC2	genetic	29674565

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of TMA7_YEAST

Related Literatures of Post-Translational Modification