| UniProt ID | SLF1_YEAST | |
|---|---|---|
| UniProt AC | Q12034 | |
| Protein Name | Protein SLF1 | |
| Gene Name | SLF1 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 447 | |
| Subcellular Localization | ||
| Protein Description | Regulates the copper-dependent mineralization of copper sulfide complexes on the cell surface in cells cultured in medium containing copper salts.. | |
| Protein Sequence | MSSQNLNDNPKNTSSAAEDKKKQTSSLKLAPIPTTSPWKSSSPDSNTVIPVEELRDISKTAKPSKNGSGSIKLTSNTKWTPITPSVIISGSKDTNSKSGKNSKNSKTNKKMKKRGKYNNDINKKDFNGQTNSTSEISNVSNLESKPLDANAKVNIHSSSGATANGNIKRITNNNNSTNGRQSRNYQNRNGKTRYNNNSRHSQAANNAISFPNNYQARPEYIPNASHWLNNNSRNSYKQLSYFRQQQYYNNINYQQQLQTPYYYSMEPIFKSIESIKNQIEFYFSEENLKTDEFLRSKFKKANDGFIPMSLIGKFYRMVNLSLGGDPNLILASMREVLQHKETNHLEIALGSIEGAQKNMADDFNPLENYFIRRENWAEYAMESNFDENDDETEKYNIEKLLGPNDLDNYSYMGYPNFFPSNENGKKSQSYDQGEISRQFEQNLQIND | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 2 | Phosphorylation | ------MSSQNLNDN ------CCCCCCCCC | 40.40 | 30377154 | |
| 40 | Phosphorylation | PTTSPWKSSSPDSNT CCCCCCCCCCCCCCC | 31.98 | 22369663 | |
| 41 | Phosphorylation | TTSPWKSSSPDSNTV CCCCCCCCCCCCCCE | 42.01 | 22369663 | |
| 42 | Phosphorylation | TSPWKSSSPDSNTVI CCCCCCCCCCCCCEE | 39.56 | 22369663 | |
| 45 | Phosphorylation | WKSSSPDSNTVIPVE CCCCCCCCCCEEEHH | 37.47 | 22369663 | |
| 47 | Phosphorylation | SSSPDSNTVIPVEEL CCCCCCCCEEEHHHH | 24.62 | 22369663 | |
| 133 | Phosphorylation | FNGQTNSTSEISNVS CCCCCCCCHHCCCCC | 32.23 | 28889911 | |
| 134 | Phosphorylation | NGQTNSTSEISNVSN CCCCCCCHHCCCCCC | 32.52 | 28889911 | |
| 176 | Phosphorylation | RITNNNNSTNGRQSR ECCCCCCCCCCCCCC | 25.93 | 21551504 | |
| 182 | Phosphorylation | NSTNGRQSRNYQNRN CCCCCCCCCCCCCCC | 22.57 | 21551504 | |
| 427 | Phosphorylation | SNENGKKSQSYDQGE CCCCCCCCCCCCHHH | 28.04 | 23749301 | |
| 429 | Phosphorylation | ENGKKSQSYDQGEIS CCCCCCCCCCHHHHH | 37.45 | 28889911 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of SLF1_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of SLF1_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of SLF1_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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| Phosphorylation | |
| Reference | PubMed |
| "A multidimensional chromatography technology for in-depthphosphoproteome analysis."; Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.; Mol. Cell. Proteomics 7:1389-1396(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-40; SER-42; SER-45 ANDSER-427, AND MASS SPECTROMETRY. | |
| "Quantitative phosphoproteomics applied to the yeast pheromonesignaling pathway."; Gruhler A., Olsen J.V., Mohammed S., Mortensen P., Faergeman N.J.,Mann M., Jensen O.N.; Mol. Cell. Proteomics 4:310-327(2005). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-42, AND MASSSPECTROMETRY. | |