PFA5_YEAST - dbPTM
PFA5_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID PFA5_YEAST
UniProt AC Q03289
Protein Name Palmitoyltransferase PFA5
Gene Name PFA5
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 374
Subcellular Localization Membrane
Multi-pass membrane protein.
Protein Description
Protein Sequence MALSWNIRIRRRSWFRFILPIIVLGLLCYGTWAYCHKLCYEQVDKRLRQKSVSVGLICAVCFLDVVVIFIWLQIVILVGPGTQPHVAPFLILPIASEEKTSNTSQNTSVEYDAVVPPKCYQSDPHGYPIWCSECQSLKMERTHHSSELGHCIPRFDHYCMWIGTVIGRDNYRLFVQFAAYFSTLLLIMWVSICVYIRIITQHNHNYSPNLNANIISTLVFAILGWLLTASLLASSIFYMSQNKTSLEAIIDSKRKKFGTRKIFCYYSEANKLRFVVEFDRSEFHSFWDKKSILANIKDFMGSNILMWIIPLGKPYTSRCKSDGKSGSKTTLVEILGPYEETLSDYTIQAIEDKISRGEYLATLRASGDDSDPAY
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
158PhosphorylationCIPRFDHYCMWIGTV
CCCCCCCEEEHHHHE
5.9528889911
355PhosphorylationQAIEDKISRGEYLAT
HHHHHHCCCCCHHHH
39.7219779198

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of PFA5_YEAST !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of PFA5_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of PFA5_YEAST !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
YGK8_YEASTYGL108Cphysical
19416974
GPI1_YEASTGPI1physical
16093310
SLX5_YEASTSLX5genetic
27708008
AGP1_YEASTAGP1genetic
27708008
ODO2_YEASTKGD2genetic
27708008
SAC3_YEASTSAC3genetic
27708008
RAD4_YEASTRAD4genetic
27708008
CHO2_YEASTCHO2genetic
27708008
YHK5_YEASTYHR045Wgenetic
27708008
CSN12_YEASTYJR084Wgenetic
27708008
ELM1_YEASTELM1genetic
27708008
PRY2_YEASTPRY2genetic
27708008
OCA2_YEASTOCA2genetic
27708008
SUCA_YEASTLSC1genetic
27708008

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of PFA5_YEAST

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Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"A multidimensional chromatography technology for in-depthphosphoproteome analysis.";
Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.;
Mol. Cell. Proteomics 7:1389-1396(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-158, AND MASSSPECTROMETRY.

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