GAL2_YEAST - dbPTM
GAL2_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID GAL2_YEAST
UniProt AC P13181
Protein Name Galactose transporter
Gene Name GAL2
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 574
Subcellular Localization Membrane
Multi-pass membrane protein.
Protein Description GAL2 is a facilitated diffusion transporter required for both the high-affinity galactokinase-dependent and low-affinity galactokinase-independent galactose transport processes..
Protein Sequence MAVEENNMPVVSQQPQAGEDVISSLSKDSHLSAQSQKYSNDELKAGESGSEGSQSVPIEIPKKPMSEYVTVSLLCLCVAFGGFMFGWDTGTISGFVVQTDFLRRFGMKHKDGTHYLSNVRTGLIVAIFNIGCAFGGIILSKGGDMYGRKKGLSIVVSVYIVGIIIQIASINKWYQYFIGRIISGLGVGGIAVLCPMLISEIAPKHLRGTLVSCYQLMITAGIFLGYCTNYGTKSYSNSVQWRVPLGLCFAWSLFMIGALTLVPESPRYLCEVNKVEDAKRSIAKSNKVSPEDPAVQAELDLIMAGIEAEKLAGNASWGELFSTKTKVFQRLLMGVFVQMFQQLTGNNYFFYYGTVIFKSVGLDDSFETSIVIGVVNFASTFFSLWTVENLGHRKCLLLGAATMMACMVIYASVGVTRLYPHGKSQPSSKGAGNCMIVFTCFYIFCYATTWAPVAWVITAESFPLRVKSKCMALASASNWVWGFLIAFFTPFITSAINFYYGYVFMGCLVAMFFYVFFFVPETKGLSLEEIQELWEEGVLPWKSEGWIPSSRRGNNYDLEDLQHDDKPWYKAMLE
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
23PhosphorylationQAGEDVISSLSKDSH
CCCHHHHHHHCCCCH		25.6928889911
24PhosphorylationAGEDVISSLSKDSHL
CCHHHHHHHCCCCHH		26.0728889911
26PhosphorylationEDVISSLSKDSHLSA
HHHHHHHCCCCHHHH		36.0428889911
29PhosphorylationISSLSKDSHLSAQSQ
HHHHCCCCHHHHCCC		30.0228889911
32PhosphorylationLSKDSHLSAQSQKYS
HCCCCHHHHCCCCCC		20.8828889911
35PhosphorylationDSHLSAQSQKYSNDE
CCHHHHCCCCCCCCC		28.4928889911
38PhosphorylationLSAQSQKYSNDELKA
HHHCCCCCCCCCCCC		12.6928889911
39PhosphorylationSAQSQKYSNDELKAG
HHCCCCCCCCCCCCC		44.8628889911
48PhosphorylationDELKAGESGSEGSQS
CCCCCCCCCCCCCCC		46.8628889911
50PhosphorylationLKAGESGSEGSQSVP
CCCCCCCCCCCCCCC		48.3328889911
53PhosphorylationGESGSEGSQSVPIEI
CCCCCCCCCCCCCCC		18.4128889911
55PhosphorylationSGSEGSQSVPIEIPK
CCCCCCCCCCCCCCC		31.4028889911
226PhosphorylationTAGIFLGYCTNYGTK
HHHHHHHHHHCCCCC		9.7628889911
228PhosphorylationGIFLGYCTNYGTKSY
HHHHHHHHCCCCCCC		24.0028889911
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources
-KUbiquitinationE3 ubiquitin ligaseGRR1P24814
PMID:22199232
-KUbiquitinationE3 ubiquitin ligaseRSP5P39940
PMID:22199232
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of GAL2_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of GAL2_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
GAL1_YEASTGAL1genetic
18421797
GAL7_YEASTGAL7genetic
18421797
GAL10_YEASTGAL10genetic
18421797
SNF3_YEASTSNF3genetic
20014043
SLX5_YEASTSLX5genetic
20093466
TPS2_YEASTTPS2genetic
20093466
GLO2_YEASTGLO2genetic
20093466
APQ12_YEASTAPQ12genetic
20093466
SNX4_YEASTSNX4genetic
20093466
VPS55_YEASTVPS55genetic
20093466
CBT1_YEASTCBT1genetic
20093466
COA4_YEASTCOA4genetic
20093466
GTR1_YEASTGTR1genetic
20093466
SWS2_YEASTSWS2genetic
20093466
TOR2_YEASTTOR2genetic
20526336
SUR1_YEASTSUR1genetic
21623372
CBS_YEASTCYS4genetic
21623372
ATPK_YEASTATP17genetic
21623372
HXKB_YEASTHXK2genetic
21623372
KMO_YEASTBNA4genetic
21623372
BLH1_YEASTLAP3genetic
21589890
GAL7_YEASTGAL7genetic
21589890
GAL80_YEASTGAL80genetic
21589890
GLO2_YEASTGLO2genetic
27708008
BCS1_YEASTBCS1genetic
27708008
ASK10_YEASTASK10genetic
27708008
QCR9_YEASTQCR9genetic
27708008
SNX4_YEASTSNX4genetic
27708008
VPS55_YEASTVPS55genetic
27708008
CBT1_YEASTCBT1genetic
27708008
COA4_YEASTCOA4genetic
27708008
GTR1_YEASTGTR1genetic
27708008
NGL2_YEASTNGL2genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of GAL2_YEAST

loading...

Related Literatures of Post-Translational Modification

TOP
© 2024 Institute of Bioinformatics and Systems Biology, NYCU | Designed by : BiOmics Laboratory