| UniProt ID | TIM9_YEAST | |
|---|---|---|
| UniProt AC | O74700 | |
| Protein Name | Mitochondrial import inner membrane translocase subunit TIM9 | |
| Gene Name | TIM9 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 87 | |
| Subcellular Localization |
Mitochondrion inner membrane Peripheral membrane protein Intermembrane side . Mitochondrion intermembrane space . |
|
| Protein Description | Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. Compared to TIM10, it may have a strong structural role.. | |
| Protein Sequence | MDALNSKEQQEFQKVVEQKQMKDFMRLYSNLVERCFTDCVNDFTTSKLTNKEQTCIMKCSEKFLKHSERVGQRFQEQNAALGQGLGR | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
|
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 1 | Acetylation | -------MDALNSKE -------CCCCCHHH | 6.49 | 22814378 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of TIM9_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of TIM9_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of TIM9_YEAST !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| TIM10_YEAST | TIM10 | physical | 12138093 | |
| TIM10_YEAST | TIM10 | physical | 11483513 | |
| TIM10_YEAST | TIM10 | physical | 9822593 | |
| TIM10_YEAST | TIM10 | physical | 11867522 | |
| SPT7_YEAST | SPT7 | genetic | 12923659 | |
| TIM10_YEAST | TIM10 | physical | 16039669 | |
| TIM10_YEAST | TIM10 | physical | 18022191 | |
| TIM9_YEAST | TIM9 | physical | 18022191 | |
| TIM9_YEAST | TIM9 | physical | 12138093 | |
| TIM10_YEAST | TIM10 | physical | 19667201 | |
| MIA40_YEAST | MIA40 | physical | 19667201 | |
| TIM22_YEAST | TIM22 | physical | 19667201 | |
| TIM10_YEAST | TIM10 | physical | 18270693 | |
| TIM10_YEAST | TIM10 | physical | 18421298 | |
| MIA40_YEAST | MIA40 | physical | 17978092 | |
| TIM10_YEAST | TIM10 | physical | 17978092 | |
| MIA40_YEAST | MIA40 | physical | 21944719 | |
| TIM10_YEAST | TIM10 | physical | 21944719 | |
| TIM12_YEAST | TIM12 | physical | 21944719 | |
| TIM18_YEAST | TIM18 | physical | 21944719 | |
| TIM22_YEAST | TIM22 | physical | 21944719 | |
| TIM54_YEAST | TIM54 | physical | 21944719 | |
| YME1_YEAST | YME1 | genetic | 23036860 | |
| TIM10_YEAST | TIM10 | physical | 22095685 | |
| YME1_YEAST | YME1 | genetic | 26182355 | |
| TIM10_YEAST | TIM10 | physical | 26182355 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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