HOT13_YEAST - dbPTM
HOT13_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID HOT13_YEAST
UniProt AC P36078
Protein Name Helper of Tim protein 13
Gene Name HOT13
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 116
Subcellular Localization Mitochondrion intermembrane space . Mitochondrion membrane
Peripheral membrane protein .
Protein Description Required for the assembly or recycling of the small Tim proteins in the mitochondrial intermembrane, thereby participating in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. Probably acts by facilitating the formation of disulfide bonds in small Tim proteins..
Protein Sequence MIETAIYGKTVDDQSRCVHWHLPKDVIAIRFKCCDKYYACFECHQELSSHPLEKYDLLDDANKHLIICGVCRHEMTFAEYYDYNSNLICPNCRSPFNPGCKLHYHLYFQNPPPAMC
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
9UbiquitinationIETAIYGKTVDDQSR
CEEEEECCCCCCCCC
28.5324961812

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of HOT13_YEAST !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of HOT13_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of HOT13_YEAST !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
MIA40_YEASTMIA40physical
18787558
SEC22_YEASTSEC22genetic
27708008
ODPB_YEASTPDB1genetic
27708008
MTU1_YEASTSLM3genetic
27708008
RPN6_YEASTRPN6genetic
27708008
ACT_YEASTACT1genetic
27708008
CDC12_YEASTCDC12genetic
27708008
SPC97_YEASTSPC97genetic
27708008
HACD_YEASTPHS1genetic
27708008
CBF3B_YEASTCEP3genetic
27708008
RNA1_YEASTRNA1genetic
27708008
CAP_YEASTSRV2genetic
27708008
DBP6_YEASTDBP6genetic
27708008
TYSY_YEASTCDC21genetic
27708008
GPI2_YEASTGPI2genetic
27708008
DIB1_YEASTDIB1genetic
27708008
HAP3_YEASTHAP3genetic
27708008
HPC2_YEASTHPC2genetic
27708008
SGF29_YEASTSGF29genetic
27708008
PAT1_YEASTPAT1genetic
27708008
S2538_YEASTYDL119Cgenetic
27708008
CRD1_YEASTCRD1genetic
27708008
TGL2_YEASTTGL2genetic
27708008
RM01_YEASTMRPL1genetic
27708008
RTR1_YEASTRTR1genetic
27708008
CGR1_YEASTCGR1genetic
27708008
YG036_YEASTYGL036Wgenetic
27708008
PYC1_YEASTPYC1genetic
27708008
GTS1_YEASTGTS1genetic
27708008
PEF1_YEASTPEF1genetic
27708008
YHJ5_YEASTNEL1genetic
27708008
HTD2_YEASTHTD2genetic
27708008
YHU0_YEASTYHR140Wgenetic
27708008
LPLA_YEASTAIM22genetic
27708008
ASF1_YEASTASF1genetic
27708008
CSN12_YEASTYJR084Wgenetic
27708008
MIC60_YEASTMIC60genetic
27708008
SA190_YEASTSAP190genetic
27708008
UPS1_YEASTUPS1genetic
27708008
ADY4_YEASTADY4genetic
27708008
LIPB_YEASTLIP2genetic
27708008
ATG23_YEASTATG23genetic
27708008
ATG16_YEASTATG16genetic
27708008
ARK1_YEASTARK1genetic
27708008
EFM6_YEASTYNL024Cgenetic
27708008
CUZ1_YEASTCUZ1genetic
27708008
TOP1_YEASTTOP1genetic
27708008
ESC8_YEASTESC8genetic
27708008
YO024_YEASTYOL024Wgenetic
27708008
OPI10_YEASTOPI10genetic
27708008
DCAM_YEASTSPE2genetic
27708008
RTG1_YEASTRTG1genetic
27708008
ATG34_YEASTATG34genetic
27708008
HMI1_YEASTHMI1genetic
27708008
GAS4_YEASTGAS4genetic
27708008
PDR5_YEASTPDR5genetic
27708008
GAC1_YEASTGAC1genetic
27708008
SERC_YEASTSER1genetic
27708008
SCP1_YEASTSCP1genetic
27708008
TRM44_YEASTTRM44genetic
27708008
SRL4_YEASTSRL4genetic
27708008
SUR1_YEASTSUR1genetic
27708008
PET20_YEASTPET20genetic
27708008
NEW1_YEASTNEW1genetic
27708008
ENV7_YEASTENV7genetic
27708008
YME1_YEASTYME1genetic
27708008

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of HOT13_YEAST

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Related Literatures of Post-Translational Modification

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