dbPTM

MPA43_YEAST - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	MPA43_YEAST
UniProt AC	P53583
Protein Name	Protein MPA43
Gene Name	MPA43
Organism	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length	542
Subcellular Localization
Protein Description
Protein Sequence	MNSSLQVGIGIDVGSSSARIGVYNYYNDALLEMAQEPVPYYQDSSKKSWKFWQKSTEIIKALQKCLQKLNIREYEVKSCGVSATCSLAIFERDRTSNMLIPYPNEDNVIFWMDSSAVNECQWLNMQCPQQLLDYLGGKFVPEMGVPKLKYFLDEYSHLRDKHFHIFDLHQYIAYELSRLYEWNIEGLLGRENLNGIGNDGEVSGWSSSFYKNIINLPSNVSIGTTSLVANKHISTTVVRSCIDSYASWFAVASPHLETSLFMIAGTSSCYMYGTTISDTRIPGVWGPFDTILDNRGDFSVYAAGQSCTGKLIEHLFESHPCARKILKDGADIYQVLEQTIRDIEKNNGLSIHILTKDMFFYGDYEGNRTPFADPRIKGSFIGESTDTSMLNLTYKYICILEFLSFQTKLIIDTFQNENSNIHIKELRISGSQAKNERLLSLISLVNNGVAIIKPKENVDMMGIKGAYVLAKSAKEKKQLADVITERDISNDSEKFESLAEYRLGNDSILLRKLLCVKYHIHLDMAKQQKRYHKLVDEVFQHL

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
4	Phosphorylation	----MNSSLQVGIGI ----CCCCCEEEEEE	20.16	28889911
15	Phosphorylation	GIGIDVGSSSARIGV EEEEECCCCCCEEEE	22.44	28889911
17	Phosphorylation	GIDVGSSSARIGVYN EEECCCCCCEEEEEH	24.22	28889911
48	Phosphorylation	YQDSSKKSWKFWQKS CCCCCCCCHHHHHHH	38.95	30377154
443	Phosphorylation	ERLLSLISLVNNGVA HHHHHHHHHHHCCEE	31.40	25521595

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of MPA43_YEAST !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of MPA43_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of MPA43_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
PABS_YEAST	ABZ1	physical	16429126
TSA1_YEAST	TSA1	physical	16429126
MPA43_YEAST	MPA43	physical	18719252
KA120_YEAST	KAP120	physical	18719252
MDM10_YEAST	MDM10	genetic	21987634
BPH1_YEAST	BPH1	genetic	21987634
TPS2_YEAST	TPS2	genetic	21987634
DOP1_YEAST	DOP1	genetic	21987634
SSD1_YEAST	SSD1	genetic	21987634
UGO1_YEAST	UGO1	genetic	21987634
ZUO1_YEAST	ZUO1	genetic	21987634
PT130_YEAST	PET130	genetic	21987634
MMM1_YEAST	MMM1	genetic	21987634
GEP5_YEAST	GEP5	genetic	21987634
IPYR2_YEAST	PPA2	genetic	21987634
PFD4_YEAST	GIM3	genetic	21987634
PSD1_YEAST	PSD1	genetic	21987634
MDM32_YEAST	MDM32	genetic	21987634
GEP3_YEAST	GEP3	genetic	21987634
ASK10_YEAST	ASK10	genetic	27708008
ELO2_YEAST	ELO2	genetic	27708008
PEX19_YEAST	PEX19	genetic	27708008
LSB3_YEAST	LSB3	genetic	27708008
YOR1_YEAST	YOR1	genetic	27708008
EMC5_YEAST	EMC5	genetic	27708008
TED1_YEAST	TED1	genetic	27708008
UBI4P_YEAST	UBI4	genetic	27708008
YMS4_YEAST	YMR034C	genetic	27708008
YM01_YEAST	YMR111C	genetic	27708008
KTR1_YEAST	KTR1	genetic	27708008
MEOX2_HUMAN	MEOX2	physical	27107014

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of MPA43_YEAST

Related Literatures of Post-Translational Modification