dbPTM

MPH3_YEAST - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	MPH3_YEAST
UniProt AC	P0CE00
Protein Name	Alpha-glucosides permease MPH3
Gene Name	MPH3
Organism	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length	602
Subcellular Localization	Cell membrane Multi-pass membrane protein.
Protein Description	High-affinity uptake of maltose and maltotriose. Also transports alpha-methylglucoside, glucose and turanose but not melezitose or trehalose..
Protein Sequence	MKNLSFLINRRKENTSDSNVYPGKAKSHEPSWIEMDDQTKKDGLDIVHVEFSPDTRAPSDSNKVITEIFDATEDAKEADESERGMPLATALNTYPKAAAWSLLVSTTLIMEGYDTAILGAFYALPIFQRKFGSQNDKTGEWEISASWQIGLTLCYMAGEIVGLQLTGPSVDLVGNRYTLIIALFFLAAFTFILYFCNSLGMIAVGQALCGMPWGCFQCLTVSYASEICPLALRYYLTTYSNLCWLFGQLFAAGIMKNSQKKYADSELGYKLPFALQWILPVPLALGIFFAPESPWWLVKKGRFDEARRSLRRTLSGKGPEKEILVTLEVDKIKVTIDKEKRLTSKEGSYSDCFEDKINRRRTRITCLCWAGQATCGSILIGYSTYFYEKAGVSTEMSFTFSIIQYCLGICATFLSWWASKYFGRYDLYAFGLAFQTIVFFIIGGLGCSSTHGSKMGSGSLLMAVAFFYNLGIAPVVFCLVSEMPSSRLRTKTIILARNTYNVVSIICSVLILYQLNSKKWNWGAKSGFFWGVLCFCTLIWAVVDLPETAGKTFVEINELFKLGVSARKFKSTKVDPFVVKTPPKDVSHNDPKGDIEASIAEE

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
262	Phosphorylation	MKNSQKKYADSELGY CHHHHHHHCCCHHCC	23.76	27017623
265	Phosphorylation	SQKKYADSELGYKLP HHHHHCCCHHCCCHH	26.92	27017623
315	Phosphorylation	RSLRRTLSGKGPEKE HHHHHHHCCCCCCCE	37.53	29136822

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of MPH3_YEAST !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of MPH3_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of MPH3_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
PHO88_YEAST	PHO88	physical	16093310
ELO3_YEAST	ELO3	physical	16093310
KPR4_YEAST	PRS4	genetic	21623372
IPT1_YEAST	IPT1	genetic	21623372
THRC_YEAST	THR4	genetic	21623372
GUAD_YEAST	GUD1	genetic	21623372
PYRC_YEAST	URA4	genetic	21623372
EXG2_YEAST	EXG2	genetic	21623372
KAPS_YEAST	MET14	genetic	21623372
COX6_YEAST	COX6	genetic	21623372
CDA2_YEAST	CDA2	genetic	21623372
COQ3_YEAST	COQ3	genetic	21623372
THI20_YEAST	THI20	genetic	21623372
DHE2_YEAST	GDH2	genetic	21623372
TPS1_YEAST	TPS1	genetic	21623372
GPX2_YEAST	GPX2	genetic	21623372
GAL2_YEAST	GAL2	genetic	21623372
ADH4_YEAST	ADH4	genetic	21623372
IAH1_YEAST	IAH1	genetic	21623372
ECM38_YEAST	ECM38	genetic	21623372
YM71_YEAST	YMR226C	genetic	21623372
GAL1_YEAST	GAL1	genetic	21623372
CHMU_YEAST	ARO7	genetic	21623372
MCR1_YEAST	MCR1	genetic	21623372
GYS2_YEAST	GSY2	genetic	21623372
GSH1_YEAST	GSH1	genetic	21623372
MET22_YEAST	MET22	genetic	21623372
THI3_YEAST	THI3	genetic	21623372
STDH_YEAST	CHA1	genetic	21623372
PYRD_YEAST	URA1	genetic	21623372
CHO2_YEAST	CHO2	genetic	21623372
PMG3_YEAST	GPM3	genetic	21623372
URH1_YEAST	URH1	genetic	21623372
PDC6_YEAST	PDC6	genetic	21623372
IDH1_YEAST	IDH1	genetic	21623372
GLO2_YEAST	GLO2	genetic	21623372
GLG1_YEAST	GLG1	genetic	21623372
INP54_YEAST	INP54	genetic	21623372

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of MPH3_YEAST

Related Literatures of Post-Translational Modification