HRQ1_YEAST - dbPTM
HRQ1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID HRQ1_YEAST
UniProt AC Q05549
Protein Name ATP-dependent helicase HRQ1 {ECO:0000305}
Gene Name HRQ1 {ECO:0000303|PubMed:18701350}
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 1077
Subcellular Localization Nucleus .
Protein Description Helicase with 3'-5' helicase activity involved in genome stability. [PubMed: 23456718]
Protein Sequence MEEGPIKKKLKSAGQGSGKTDAFRNFEQFFFRLNTLYTFLICRKHVVPTFKTLCGPIETALKRTVTKEDLAMVMALMPRECVFKYIDENQIYTETKIFDFNNGGFQQKENDIFELKDVDDQNQTQKSTQLLIFEFIDGTMQRSWSASDRFSQIKIPTYTTEEMKKMISKREALFKSRLREFILEKEKANLDPFSELTNLAQKYIPRERDYEDPIEAMMKAKQESNEMSIPNYSNNSVITTIPQMIEKLKSTEFYASQIKHCFTIPSRTAKYKGLCFELAPEVYQGMEHENFYSHQADAINSLHQGENVIITTSTSSGKSLIYQLAAIDLLLKDPESTFMYIFPTKALAQDQKRAFKVILSKIPELKNAVVDTYDGDTEPEERAYIRKNARVIFTNPDMIHTSILPNHANWRHFLYHLKLVVVDELHIYKGLFGSHVALVMRRLLRLCHCFYENSGLQFISCSATLKSPVQHMKDMFGINEVTLIHEDGSPTGAKHLVVWNPPILPQHERKRENFIRESAKILVQLILNNVRTIAFCYVRRVCELLMKEVRNIFIETGREDLVTEVMSYRGGYSASDRRKIEREMFHGNLKAVISTNALELGIDIGGLDAVLMCGFPLSMANFHQQSGRAGRRNNDSLTLVVASDSPVDQHYVAHPESLLEVNNFESYQDLVLDFNNILILEGHIQCAAFELPINFERDKQYFTESHLRKICVERLHHNQDGYHASNRFLPWPSKCVSLRGGEEDQFAVVDITNGRNIIIEEIEASRTSFTLYDGGIFIHQGYPYLVKEFNPDERYAKVQRVDVDWVTNQRDFTDVDPQEIELIRSLRNSDVPVYFGKIKTTIIVFGFFKVDKYKRIIDAIETHNPPVIINSKGLWIDMPKYALEICQKKQLNVAGAIHGAQHAIMGMLPRFIVAGVDEIQTECKAPEKEFAERQTKRKRPARLIFYDSKGGKYGSGLCVKAFEHIDDIIESSLRRIEECPCSDGCPDCVAASFCKENSLVLSKPGAQVVLHCILGHSEDSFIDLIKDGPEPNMPEIKVETVIPVSEHVNFSDDFKIIDVRRATKDDTHTNEIIKKEI
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
17PhosphorylationLKSAGQGSGKTDAFR
HHHCCCCCCCCHHHH		29.2728889911
154UbiquitinationSDRFSQIKIPTYTTE
CCCHHCCCCCCCCHH		34.69-
224PhosphorylationMMKAKQESNEMSIPN
HHHHHHHHCCCCCCC		35.2828889911
240PhosphorylationSNNSVITTIPQMIEK
CCCCCCCCHHHHHHH		21.3828889911
366UbiquitinationLSKIPELKNAVVDTY
HHCCHHHHHCEEECC		40.9917644757
872UbiquitinationPPVIINSKGLWIDMP
CCEEEECCCEEEECC		54.2417644757
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of HRQ1_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of HRQ1_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of HRQ1_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
SGS1_YEASTSGS1genetic
23456718
RAD51_YEASTRAD51genetic
24682993
RAD52_YEASTRAD52genetic
24682993
RAD5_YEASTRAD5genetic
24682993
DPOZ_YEASTREV3genetic
24682993
RAD7_YEASTRAD7genetic
24682993
RAD26_YEASTRAD26genetic
24682993
RPB9_YEASTRPB9genetic
24682993
RAD4_YEASTRAD4physical
24682993
ASF1_YEASTASF1genetic
24700328
CHL1_YEASTCHL1genetic
24700328
CGS5_YEASTCLB5genetic
24700328
CTF4_YEASTCTF4genetic
24700328
DCC1_YEASTDCC1genetic
24700328
DDC1_YEASTDDC1genetic
24700328
MMS1_YEASTMMS1genetic
24700328
MMS22_YEASTMMS22genetic
24700328
MRE11_YEASTMRE11genetic
24700328
RAD17_YEASTRAD17genetic
24700328
RAD24_YEASTRAD24genetic
24700328
RAD52_YEASTRAD52genetic
24700328
RAD54_YEASTRAD54genetic
24700328
RAD55_YEASTRAD55genetic
24700328
RAD57_YEASTRAD57genetic
24700328
RAD59_YEASTRAD59genetic
24700328
CUL8_YEASTRTT101genetic
24700328
RT109_YEASTRTT109genetic
24700328
COM1_YEASTSAE2genetic
24700328
CYC8_YEASTCYC8genetic
24700328
GMH1_YEASTGMH1genetic
24700328
ODPA_YEASTPDA1genetic
24700328
ARP4_YEASTARP4genetic
24700328
BAS1_YEASTBAS1genetic
24700328
BMH1_YEASTBMH1genetic
24700328
BRE1_YEASTBRE1genetic
24700328
ERG5_YEASTERG5genetic
24700328
ERJ5_YEASTERJ5genetic
24700328
GCN1_YEASTGCN1genetic
24700328
GCN20_YEASTGCN20genetic
24700328
GET2_YEASTGET2genetic
24700328
GNP1_YEASTGNP1genetic
24700328
HPC2_YEASTHPC2genetic
24700328
IRA2_YEASTIRA2genetic
24700328
ODP2_YEASTLAT1genetic
24700328
LGE1_YEASTLGE1genetic
24700328
LST4_YEASTLST4genetic
24700328
MET18_YEASTMET18genetic
24700328
MFT1_YEASTMFT1genetic
24700328
MKS1_YEASTMKS1genetic
24700328
MRC1_YEASTMRC1genetic
24700328
NPR1_YEASTNPR1genetic
24700328
PBS2_YEASTPBS2genetic
24700328
ODPB_YEASTPDB1genetic
24700328
PDE2_YEASTPDE2genetic
24700328
ATC1_YEASTPMR1genetic
24700328
DPOD3_YEASTPOL32genetic
24700328
PALH_YEASTRIM21genetic
24700328
RL34B_YEASTRPL34Bgenetic
24700328
RS21B_YEASTRPS21Bgenetic
24700328
RTF1_YEASTRTF1genetic
24700328
RTG3_YEASTRTG3genetic
24700328
SDC1_YEASTSDC1genetic
24700328
SEC22_YEASTSEC22genetic
24700328
SEC66_YEASTSEC66genetic
24700328
SEC72_YEASTSEC72genetic
24700328
SGF73_YEASTSGF73genetic
24700328
SNX4_YEASTSNX4genetic
24700328
ATC6_YEASTSPF1genetic
24700328
TF2B_YEASTSUA7genetic
24700328
SWD1_YEASTSWD1genetic
24700328
SWD3_YEASTSWD3genetic
24700328
SWI4_YEASTSWI4genetic
24700328
SYC1_YEASTSYC1genetic
24700328
UBA3_YEASTUBA3genetic
24700328
UBP15_YEASTUBP15genetic
24700328
UBP6_YEASTUBP6genetic
24700328
URE2_YEASTURE2genetic
24700328
VPS8_YEASTVPS8genetic
24700328
TBP7_YEASTYTA7genetic
24700328
AIM21_YEASTAIM21genetic
24700328
ELO2_YEASTELO2genetic
24700328
AP3S_YEASTAPS3genetic
24700328
ARO1_YEASTARO1genetic
24700328
ARP7_YEASTARP7genetic
24700328
GGPPS_YEASTBTS1genetic
24700328
BUL1_YEASTBUL1genetic
24700328
CAPZA_YEASTCAP1genetic
24700328
COQ2_YEASTCOQ2genetic
24700328
CUE3_YEASTCUE3genetic
24700328
CY1_YEASTCYT1genetic
24700328
DCR2_YEASTDCR2genetic
24700328
HOS2_YEASTHOS2genetic
24700328
MSS18_YEASTMSS18genetic
24700328
NGL2_YEASTNGL2genetic
24700328
PT130_YEASTPET130genetic
24700328
THI6_YEASTTHI6genetic
24700328
YMZ2_YEASTYMR102Cgenetic
24700328
DAL81_YEASTDAL81genetic
24700328
FKS1_YEASTFKS1genetic
24700328
GFD1_YEASTGFD1genetic
24700328
GFD2_YEASTGFD2genetic
24700328
MMS2_YEASTMMS2genetic
24700328
MOG1_YEASTMOG1genetic
24700328
MPH1_YEASTMPH1genetic
24700328
MSH4_YEASTMSH4genetic
24700328
PET18_YEASTPET18genetic
24700328
PPA5_YEASTPHO5genetic
24700328
RAD10_YEASTRAD10genetic
24700328
RAD18_YEASTRAD18genetic
24700328
FEN1_YEASTRAD27genetic
24700328
REV1_YEASTREV1genetic
24700328
DPOZ_YEASTREV3genetic
24700328
REV7_YEASTREV7genetic
24700328
RV161_YEASTRVS161genetic
24700328
SAK1_YEASTSAK1genetic
24700328
SCS7_YEASTSCS7genetic
24700328
SRO9_YEASTSRO9genetic
24700328
STP1_YEASTSTP1genetic
24700328
TRS33_YEASTTRS33genetic
24700328
UBC13_YEASTUBC13genetic
24700328
VMA21_YEASTVMA21genetic
24700328
YGI1_YEASTYGL081Wgenetic
24700328
YSY6_YEASTYSY6genetic
24700328
HST3_YEASTHST3genetic
24700328
ILM1_YEASTILM1genetic
24700328
KA122_YEASTKAP122genetic
24700328
ELO3_YEASTELO3genetic
24700328
HRQ1_YEASTHRQ1physical
24440721
REV1_YEASTREV1genetic
23589890
DPOZ_YEASTREV3genetic
23589890
RAD5_YEASTRAD5genetic
23589890
DPOD3_YEASTPOL32genetic
23589890
SCC1_YEASTMCD1genetic
27708008
SDA1_YEASTSDA1genetic
27708008
MCM7_YEASTMCM7genetic
27708008
PRP9_YEASTPRP9genetic
27708008
KIN28_YEASTKIN28genetic
27708008
GNA1_YEASTGNA1genetic
27708008
MOB2_YEASTMOB2genetic
27708008
ACT_YEASTACT1genetic
27708008
TAF1_YEASTTAF1genetic
27708008
MPPA_YEASTMAS2genetic
27708008
ORC1_YEASTORC1genetic
27708008
SMC5_YEASTSMC5genetic
27708008
CLP1_YEASTCLP1genetic
27708008
GPN2_YEASTGPN2genetic
27708008
HRR25_YEASTHRR25genetic
27708008
RPN7_YEASTRPN7genetic
27708008
SGS1_YEASTSGS1genetic
24440721
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of HRQ1_YEAST

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Related Literatures of Post-Translational Modification

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