MCH4_YEAST - dbPTM
MCH4_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID MCH4_YEAST
UniProt AC Q08268
Protein Name Probable transporter MCH4
Gene Name MCH4
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 501
Subcellular Localization Membrane
Multi-pass membrane protein.
Protein Description Probable transporter. Does not act in the transport of monocarboxylic acids across the plasma membrane..
Protein Sequence MLNIPIIANSKRFLFSKDHEAQSTRDHDVELETREGPSSGYNPNFNAADAILKKNSDQVDLDVNKLTNVTSRVLNTPEASLIYDDDREFPDGGLKAWLVVFGAFMGLVPVFGLINSLGAIESYISKHQLANISSSTISWIFSLYLAISFLSCILSGGYFDRNGSIGLMCTGTVIYAGGLFALANCKSVWQFILAFSVCSGLGTGILMTPLIGTVATWFLKRRGIATSISTMGGSIGGIVFPIMLRKLYKEVGFQWAIRILSFICLTCLICASVLARERTKPVVQPFKSKAEVAKWYISSVFNWRYFLEGKFLFVAIGASFAESSLTSCATYLASYSMTRGNTENVAYTMITASNAVGILGRYIPGYFADKFIGRFNVEIITISMAALFNFVMWLPFGGNTKVLWAYVCLWGFSTGSILSLTPVCIGQISKTTDFGKRYATVYLLQALVTIPVLPIGGTLIGKGTVANYNHFIIFNSALMAAGAACYIISRHICVGAKLCKF
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
11UbiquitinationIPIIANSKRFLFSKD
CCEEECCCEEEECCC
47.1523749301
17UbiquitinationSKRFLFSKDHEAQST
CCEEEECCCCCCCCC
56.6322817900
53UbiquitinationNAADAILKKNSDQVD
CHHHHHHHCCCCCCC
43.7423749301
54UbiquitinationAADAILKKNSDQVDL
HHHHHHHCCCCCCCC
59.2323749301
56PhosphorylationDAILKKNSDQVDLDV
HHHHHCCCCCCCCCH
38.0023749301
65UbiquitinationQVDLDVNKLTNVTSR
CCCCCHHHHHHHHHH
57.4423749301
70PhosphorylationVNKLTNVTSRVLNTP
HHHHHHHHHHHHCCC
16.9423749301
71PhosphorylationNKLTNVTSRVLNTPE
HHHHHHHHHHHCCCC
18.9923749301
76PhosphorylationVTSRVLNTPEASLIY
HHHHHHCCCCHHCEE
20.5328889911
80PhosphorylationVLNTPEASLIYDDDR
HHCCCCHHCEECCCC
17.4021551504
131N-linked_GlycosylationISKHQLANISSSTIS
HCHHHHCCCCHHHHH
43.18-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of MCH4_YEAST !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of MCH4_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of MCH4_YEAST !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
SC61G_YEASTSSS1genetic
27708008
SRPR_YEASTSRP101genetic
27708008
MOB2_YEASTMOB2genetic
27708008
PRS10_YEASTRPT4genetic
27708008
CHO2_YEASTCHO2genetic
27708008
NCA3_YEASTNCA3genetic
27708008
AEP2_YEASTAEP2genetic
27708008
CDC24_YEASTCDC24genetic
27708008
SYIC_YEASTILS1genetic
27708008
MPS1_YEASTMPS1genetic
27708008
NOP14_YEASTNOP14genetic
27708008
TPIS_YEASTTPI1genetic
27708008
DBF4_YEASTDBF4genetic
27708008
TAF12_YEASTTAF12genetic
27708008
GPI8_YEASTGPI8genetic
27708008
CAK1_YEASTCAK1genetic
27708008
RPN11_YEASTRPN11genetic
27708008
RRP41_YEASTSKI6genetic
27708008
ZPR1_YEASTZPR1genetic
27708008
CDC12_YEASTCDC12genetic
27708008
DNA2_YEASTDNA2genetic
27708008
RPC9_YEASTRPC17genetic
27708008
DPB11_YEASTDPB11genetic
27708008
ESS1_YEASTESS1genetic
27708008
KTHY_YEASTCDC8genetic
27708008
CDC11_YEASTCDC11genetic
27708008
GRC3_YEASTGRC3genetic
27708008
ERG27_YEASTERG27genetic
27708008
SEC22_YEASTSEC22genetic
27708008
TAD3_YEASTTAD3genetic
27708008
PRP39_YEASTPRP39genetic
27708008
ORC1_YEASTORC1genetic
27708008
TAP42_YEASTTAP42genetic
27708008
CBF3B_YEASTCEP3genetic
27708008
RNA1_YEASTRNA1genetic
27708008
LST8_YEASTLST8genetic
27708008
GPI2_YEASTGPI2genetic
27708008
CET1_YEASTCET1genetic
27708008
BUR1_YEASTSGV1genetic
27708008
PMT2_YEASTPMT2genetic
27708008
SWD1_YEASTSWD1genetic
27708008
ECM33_YEASTECM33genetic
27708008
FAT2_YEASTPCS60genetic
27708008
RMD9L_YEASTYBR238Cgenetic
27708008
GPX2_YEASTGPX2genetic
27708008
GLYM_YEASTSHM1genetic
27708008
SGF29_YEASTSGF29genetic
27708008
SOL2_YEASTSOL2genetic
27708008
NHP10_YEASTNHP10genetic
27708008
LHP1_YEASTLHP1genetic
27708008
VAM6_YEASTVAM6genetic
27708008
S2538_YEASTYDL119Cgenetic
27708008
PP2A1_YEASTPPH21genetic
27708008
VPS41_YEASTVPS41genetic
27708008
RM01_YEASTMRPL1genetic
27708008
OMS1_YEASTOMS1genetic
27708008
LCMT1_YEASTPPM1genetic
27708008
SDC1_YEASTSDC1genetic
27708008
IES5_YEASTIES5genetic
27708008
IES1_YEASTIES1genetic
27708008
ATG1_YEASTATG1genetic
27708008
PHB2_YEASTPHB2genetic
27708008
MAL12_YEASTMAL12genetic
27708008
RL8A_YEASTRPL8Agenetic
27708008
ARP1_YEASTARP1genetic
27708008
CHS7_YEASTCHS7genetic
27708008
STB5_YEASTSTB5genetic
27708008
AIM18_YEASTAIM18genetic
27708008
SDS3_YEASTSDS3genetic
27708008
VPS53_YEASTVPS53genetic
27708008
ASF1_YEASTASF1genetic
27708008
RPE_YEASTRPE1genetic
27708008
RAV1_YEASTRAV1genetic
27708008
BFA1_YEASTBFA1genetic
27708008
HIR3_YEASTHIR3genetic
27708008
VPS24_YEASTVPS24genetic
27708008
ELM1_YEASTELM1genetic
27708008
HSL1_YEASTHSL1genetic
27708008
KAPC_YEASTTPK3genetic
27708008
RM49_YEASTMRP49genetic
27708008
NNK1_YEASTNNK1genetic
27708008
EMC3_YEASTEMC3genetic
27708008
MIC60_YEASTMIC60genetic
27708008
PAM17_YEASTPAM17genetic
27708008
POM33_YEASTPOM33genetic
27708008
LDB18_YEASTLDB18genetic
27708008
BRE2_YEASTBRE2genetic
27708008
COA4_YEASTCOA4genetic
27708008
BUD6_YEASTBUD6genetic
27708008
ROM2_YEASTROM2genetic
27708008
CDC73_YEASTCDC73genetic
27708008
RM39_YEASTMRPL39genetic
27708008
RCF1_YEASTRCF1genetic
27708008
SAP30_YEASTSAP30genetic
27708008
NGL2_YEASTNGL2genetic
27708008
DYN3_YEASTDYN3genetic
27708008
HDA1_YEASTHDA1genetic
27708008
SWS2_YEASTSWS2genetic
27708008
EAF7_YEASTEAF7genetic
27708008
RCF2_YEASTRCF2genetic
27708008
ATP23_YEASTATP23genetic
27708008
MSC6_YEASTMSC6genetic
27708008
VTS1_YEASTVTS1genetic
27708008
RAD1_YEASTRAD1genetic
27708008
SVL3_YEASTSVL3genetic
27708008
GGPPS_YEASTBTS1genetic
27708008
RNY1_YEASTRNY1genetic
27708008
SPP1_YEASTSPP1genetic
27708008
PTPA2_YEASTRRD2genetic
27708008
MSS18_YEASTMSS18genetic
27708008
HDA3_YEASTHDA3genetic
27708008
QCR2_YEASTQCR2genetic
27708008

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of MCH4_YEAST

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Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"A proteomics approach to understanding protein ubiquitination.";
Peng J., Schwartz D., Elias J.E., Thoreen C.C., Cheng D.,Marsischky G., Roelofs J., Finley D., Gygi S.P.;
Nat. Biotechnol. 21:921-926(2003).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-76, AND MASSSPECTROMETRY.

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