SWT1_YEAST - dbPTM
SWT1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID SWT1_YEAST
UniProt AC Q12104
Protein Name Transcriptional protein SWT1
Gene Name SWT1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 458
Subcellular Localization Nucleus . Mainly nuclear, but might shuttle between the nucleus and the cytoplasm.
Protein Description Involved in transcription. Probably functions as a transcriptional activator..
Protein Sequence MTDEKRAFPKGNNHIRSETFNGSVSHKISESIKDIASLRPHGKYTVQDIDNIIASTSSHENRGQSGDSNGCINHDEEGDIPMCDLNDESDVEMISEYLSSQREMEAQSVANYMPKINDDLPLLNPPTLKTAFVVDTNFIISHLNTLEKLRSLSSTYHHLIIVPTTVIQELDGLKKSPDIARDNDDTTNQEHDRTIGTLARWGNDWIYKNLANLDSGLIGQKLKQSLNPGSLKDDSILDCCLYFKEILNCFVILLSNDKNLCTKALTEDILTVSFRKNMDAKIIAMRAYEENQLRFANLRDSTVNNFDQNVTSYAHIPGIETPPLQFDKVSQNVFEQVKETIFFAIDHTLRKEYGEDIGFIDYNPDKLTTIENASNYIYLFWVSVFSELFTCSKIKKNEWKSLPTVLKSKPTNLNDLRTFEQFWETVLHFLFSKFTNEEKQSLEKQIHEWKTSINAIST
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
17PhosphorylationKGNNHIRSETFNGSV
CCCCCCCCCCCCCCH
40.1524961812
19PhosphorylationNNHIRSETFNGSVSH
CCCCCCCCCCCCHHH
24.5223749301
23PhosphorylationRSETFNGSVSHKISE
CCCCCCCCHHHHHCH
22.8824961812
25PhosphorylationETFNGSVSHKISESI
CCCCCCHHHHHCHHH
22.2924961812
33AcetylationHKISESIKDIASLRP
HHHCHHHHHHHHCCC
52.9725381059
43AcetylationASLRPHGKYTVQDID
HHCCCCCCEEHHHHC
34.4125381059
401PhosphorylationIKKNEWKSLPTVLKS
CCCCCHHCCCHHHHC
40.4321126336
404PhosphorylationNEWKSLPTVLKSKPT
CCHHCCCHHHHCCCC
43.7027214570

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of SWT1_YEAST !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of SWT1_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of SWT1_YEAST !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
THO2_YEASTTHO2genetic
17030511
MFT1_YEASTMFT1genetic
17030511
THP2_YEASTTHP2genetic
17030511
SUB2_YEASTSUB2genetic
17030511
HPR1_YEASTHPR1physical
17030511
SUB2_YEASTSUB2physical
17030511
YRA1_YEASTYRA1physical
17030511
RPB1_YEASTRPO21physical
17030511
THO2_YEASTTHO2genetic
19127978
HPR1_YEASTHPR1genetic
19127978
MFT1_YEASTMFT1genetic
19127978
THP2_YEASTTHP2genetic
19127978
SUB2_YEASTSUB2genetic
19127978
SAC3_YEASTSAC3genetic
19127978
THP1_YEASTTHP1genetic
19127978
SUS1_YEASTSUS1genetic
19127978
NUP60_YEASTNUP60genetic
19127978
ESC1_YEASTESC1genetic
19127978
NOP3_YEASTNPL3genetic
19127978
MLP1_YEASTMLP1genetic
19127978
AVT5_YEASTAVT5genetic
27708008
SAC3_YEASTSAC3genetic
27708008
MON1_YEASTMON1genetic
27708008
THP2_YEASTTHP2genetic
27708008
SDHX_YEASTYJL045Wgenetic
27708008
MLP1_YEASTMLP1genetic
27708008
YL287_YEASTYLR287Cgenetic
27708008
YNO0_YEASTYNL140Cgenetic
27708008
VPS4_YEASTVPS4genetic
27708008
HSP26_YEASTHSP26genetic
29674565
SNT1_YEASTSNT1genetic
29674565
BRE1_YEASTBRE1genetic
29674565
SAC3_YEASTSAC3genetic
29674565
RS26B_YEASTRPS26Bgenetic
29674565
VPS24_YEASTVPS24genetic
29674565
SMY1_YEASTSMY1genetic
29674565
HSL1_YEASTHSL1genetic
29674565
CANB_YEASTCNB1genetic
29674565
RT109_YEASTRTT109genetic
29674565
CAP_YEASTSRV2genetic
29674565
PUS1_YEASTPUS1genetic
29674565
RLF2_YEASTRLF2genetic
29674565
ATP18_YEASTATP18genetic
29674565

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of SWT1_YEAST

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Related Literatures of Post-Translational Modification

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