BOL1_YEAST - dbPTM
BOL1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID BOL1_YEAST
UniProt AC Q3E793
Protein Name BolA-like protein 1 {ECO:0000305}
Gene Name BOL1 {ECO:0000303|PubMed:27532772, ECO:0000303|PubMed:27532773}
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 110
Subcellular Localization Mitochondrion matrix .
Protein Description Acts as a mitochondrial iron-sulfur (Fe-S) cluster assembly factor that facilitates [4Fe-4S] cluster insertion into a subset of mitochondrial proteins such as LIAS and succinate dehydrogenase (SDH). [PubMed: 27532772 Required during the last step of iron-sulfur protein assembly when the iron-sulfur cluster is inserted into the target protein]
Protein Sequence MFKRAMSTDGPVARTILKRLECGFPDYKNFAFGLYNDSHKHKGHAGVQGNVSAETHFRIEMVSKKFEGLKLPQRHRMVYSLLQDEMAQANGIHALQLSLKTPQEYESKAK
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
7Phosphorylation-MFKRAMSTDGPVAR
-CCCCCCCCCCHHHH
19823750
8PhosphorylationMFKRAMSTDGPVART
CCCCCCCCCCHHHHH
19823750
15PhosphorylationTDGPVARTILKRLEC
CCCHHHHHHHHHHCC
19823750
40AcetylationGLYNDSHKHKGHAGV
ECCCCCCCCCCCCCC
24489116

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of BOL1_YEAST !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of BOL1_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of BOL1_YEAST !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
MPA43_YEASTMPA43physical
18719252
GLRX3_YEASTGRX3physical
18719252
WRIP1_YEASTMGS1physical
18719252
GLRX4_YEASTGRX4physical
18719252
BOL3_YEASTAIM1genetic
27532773
GLRX5_YEASTGRX5physical
27532773
RPB1_YEASTRPO21genetic
27708008
ERF3_YEASTSUP35genetic
27708008
CDC1_YEASTCDC1genetic
27708008
SNU56_YEASTSNU56genetic
27708008
DPB11_YEASTDPB11genetic
27708008
CDC11_YEASTCDC11genetic
27708008
MTU1_YEASTSLM3genetic
27708008
BCS1_YEASTBCS1genetic
27708008
RV167_YEASTRVS167genetic
27708008
XRN1_YEASTXRN1genetic
27708008
SNF6_YEASTSNF6genetic
27708008
VPS53_YEASTVPS53genetic
27708008
GSH1_YEASTGSH1genetic
27708008
RS10A_YEASTRPS10Agenetic
27708008
BOL3_YEASTAIM1genetic
27532772
GLRX3_HUMANGLRX3physical
27107014
BIRC2_HUMANBIRC2physical
27107014
XIAP_HUMANXIAPphysical
27107014

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of BOL1_YEAST

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Related Literatures of Post-Translational Modification

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