dbPTM

YGL7_YEAST - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	YGL7_YEAST
UniProt AC	P53133
Protein Name	Uncharacterized protein YGL117W
Gene Name	YGL117W
Organism	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length	265
Subcellular Localization
Protein Description
Protein Sequence	MQPISIKDVESDQGKVYIVNALKDLVCKCLLEFVDIQIESFMYPDDPKCFTRIFKGNKIVNEASDKDSKVRSYPSSLGVGHSALFPLIYIRQKTNSLRFLNDPKQLPTPLVDDMNAKFKGIIKVYENLIHLYHSYQTVDCNNMNQQKLLGDLVSRGNFMLDILHGYVTIASTIVRDSKDANILIDTVNRFIHDTILFHKRIIHNSNAYTEYHVMKRGMQRNQSEETLVELEFRILDVSDVNLDNEFDDFLQHRKTSLKITHRRVI

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
7	Acetylation	-MQPISIKDVESDQG -CCCCCCEEEECCCC	49.26	25381059
15	Ubiquitination	DVESDQGKVYIVNAL EEECCCCEEEEHHHH	26.65	17644757
15	Acetylation	DVESDQGKVYIVNAL EEECCCCEEEEHHHH	26.65	25381059
23	Ubiquitination	VYIVNALKDLVCKCL EEEHHHHHHHHHHHH	46.75	17644757
28	Ubiquitination	ALKDLVCKCLLEFVD HHHHHHHHHHHHHCC	22.04	17644757
66	Ubiquitination	IVNEASDKDSKVRSY EECCCCCCCCCHHCC	62.50	23749301
68	Phosphorylation	NEASDKDSKVRSYPS CCCCCCCCCHHCCCC	38.50	27017623
123	Ubiquitination	AKFKGIIKVYENLIH HHHHHHHHHHHHHHH	36.52	17644757
147	Ubiquitination	CNNMNQQKLLGDLVS CCCCCHHHHHHHHHH	35.60	17644757
178	Ubiquitination	STIVRDSKDANILID EEHHCCCCCCCEEHH	66.21	17644757
199	Ubiquitination	HDTILFHKRIIHNSN HHHHHHEEEECCCCC	37.65	17644757
215	Ubiquitination	YTEYHVMKRGMQRNQ HHHHHHHHHHHCCCC	44.72	17644757
223	Phosphorylation	RGMQRNQSEETLVEL HHHCCCCCHHHHHEE	40.73	22369663
226	Phosphorylation	QRNQSEETLVELEFR CCCCCHHHHHEEEEE	31.86	22369663

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of YGL7_YEAST !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of YGL7_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of YGL7_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
PIR5_YEAST	YJL160C	genetic	27708008
INO4_YEAST	INO4	genetic	27708008

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of YGL7_YEAST

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"A multidimensional chromatography technology for in-depthphosphoproteome analysis."; Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.; Mol. Cell. Proteomics 7:1389-1396(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-223, AND MASSSPECTROMETRY.	18407956 [Abstract]
"Quantitative phosphoproteomics applied to the yeast pheromonesignaling pathway."; Gruhler A., Olsen J.V., Mohammed S., Mortensen P., Faergeman N.J.,Mann M., Jensen O.N.; Mol. Cell. Proteomics 4:310-327(2005). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-223, AND MASSSPECTROMETRY.	15665377 [Abstract]