RING2_HUMAN - dbPTM
RING2_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID RING2_HUMAN
UniProt AC Q99496
Protein Name E3 ubiquitin-protein ligase RING2
Gene Name RNF2
Organism Homo sapiens (Human).
Sequence Length 336
Subcellular Localization Nucleus . Chromosome . Enriched on inactive X chromosome (Xi) in female trophoblast stem (TS) cells as well as differentiating embryonic stem (ES) cells. The enrichment on Xi is transient during TS and ES cell differentiation. The association with Xi
Protein Description E3 ubiquitin-protein ligase that mediates monoubiquitination of 'Lys-119' of histone H2A (H2AK119Ub), thereby playing a central role in histone code and gene regulation. [PubMed: 15386022]
Protein Sequence MSQAVQTNGTQPLSKTWELSLYELQRTPQEAITDGLEIVVSPRSLHSELMCPICLDMLKNTMTTKECLHRFCADCIITALRSGNKECPTCRKKLVSKRSLRPDPNFDALISKIYPSRDEYEAHQERVLARINKHNNQQALSHSIEEGLKIQAMNRLQRGKKQQIENGSGAEDNGDSSHCSNASTHSNQEAGPSNKRTKTSDDSGLELDNNNAAMAIDPVMDGASEIELVFRPHPTLMEKDDSAQTRYIKTSGNATVDHLSKYLAVRLALEELRSKGESNQMNLDTASEKQYTIYIATASGQFTVLNGSFSLELVSEKYWKVNKPMELYYAPTKEHK
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
2Phosphorylation------MSQAVQTNG
------CCCCCCCCC
27.1819691289
2Acetylation------MSQAVQTNG
------CCCCCCCCC
27.1819691289
7Phosphorylation-MSQAVQTNGTQPLS
-CCCCCCCCCCCCCC
29.0828450419
10PhosphorylationQAVQTNGTQPLSKTW
CCCCCCCCCCCCCCE
29.1428450419
14PhosphorylationTNGTQPLSKTWELSL
CCCCCCCCCCEEEEH
34.4224043423
22PhosphorylationKTWELSLYELQRTPQ
CCEEEEHHHCCCCHH
15.9527642862
33PhosphorylationRTPQEAITDGLEIVV
CCHHHHHCCCCEEEE
30.9430301811
41PhosphorylationDGLEIVVSPRSLHSE
CCCEEEECCCHHCHH
12.0530278072
44PhosphorylationEIVVSPRSLHSELMC
EEEECCCHHCHHHCH
33.5426074081
47PhosphorylationVSPRSLHSELMCPIC
ECCCHHCHHHCHHHH
37.4124719451
65UbiquitinationLKNTMTTKECLHRFC
HHHCCCHHHHHHHHH
36.95-
65UbiquitinationLKNTMTTKECLHRFC
HHHCCCHHHHHHHHH
36.95-
78PhosphorylationFCADCIITALRSGNK
HHHHHHHHHHHHCCC
10.3424719451
99PhosphorylationKKLVSKRSLRPDPNF
HHHHCCHHCCCCCCH
32.2520873877
100UbiquitinationKLVSKRSLRPDPNFD
HHHCCHHCCCCCCHH
12.2221890473
116PhosphorylationLISKIYPSRDEYEAH
HHHHHCCCHHHHHHH
35.08-
120PhosphorylationIYPSRDEYEAHQERV
HCCCHHHHHHHHHHH
23.78-
133UbiquitinationRVLARINKHNNQQAL
HHHHHHHHHCCHHHH
45.3929967540
141PhosphorylationHNNQQALSHSIEEGL
HCCHHHHHHHHHHHH
20.4323663014
143PhosphorylationNQQALSHSIEEGLKI
CHHHHHHHHHHHHHH
28.4625159151
149UbiquitinationHSIEEGLKIQAMNRL
HHHHHHHHHHHHHHH
43.5622817900
168PhosphorylationKQQIENGSGAEDNGD
HHHCCCCCCCCCCCC
46.5423927012
176PhosphorylationGAEDNGDSSHCSNAS
CCCCCCCCCCCCCCC
24.3125850435
177PhosphorylationAEDNGDSSHCSNAST
CCCCCCCCCCCCCCC
33.0025850435
177UbiquitinationAEDNGDSSHCSNAST
CCCCCCCCCCCCCCC
33.0021890473
180PhosphorylationNGDSSHCSNASTHSN
CCCCCCCCCCCCCCC
29.9730576142
183PhosphorylationSSHCSNASTHSNQEA
CCCCCCCCCCCCCCC
30.7925850435
184PhosphorylationSHCSNASTHSNQEAG
CCCCCCCCCCCCCCC
27.2429496963
186PhosphorylationCSNASTHSNQEAGPS
CCCCCCCCCCCCCCC
40.0525850435
189UbiquitinationASTHSNQEAGPSNKR
CCCCCCCCCCCCCCC
60.9021890473
193PhosphorylationSNQEAGPSNKRTKTS
CCCCCCCCCCCCCCC
54.8130576142
197PhosphorylationAGPSNKRTKTSDDSG
CCCCCCCCCCCCCCC
40.0422496350
198UbiquitinationGPSNKRTKTSDDSGL
CCCCCCCCCCCCCCC
50.4932015554
199PhosphorylationPSNKRTKTSDDSGLE
CCCCCCCCCCCCCCC
36.4525159151
200PhosphorylationSNKRTKTSDDSGLEL
CCCCCCCCCCCCCCC
40.7625159151
200UbiquitinationSNKRTKTSDDSGLEL
CCCCCCCCCCCCCCC
40.7621890473
203PhosphorylationRTKTSDDSGLELDNN
CCCCCCCCCCCCCCC
50.7122496350
212UbiquitinationLELDNNNAAMAIDPV
CCCCCCCCEEEEEEC
10.7521890473
247PhosphorylationDDSAQTRYIKTSGNA
CCCCCCEEEEECCCC
15.34-
248UbiquitinationDSAQTRYIKTSGNAT
CCCCCEEEEECCCCC
3.3721890473
249AcetylationSAQTRYIKTSGNATV
CCCCEEEEECCCCCH
27.9220167786
249UbiquitinationSAQTRYIKTSGNATV
CCCCEEEEECCCCCH
27.9222817900
249SumoylationSAQTRYIKTSGNATV
CCCCEEEEECCCCCH
27.9228112733
251UbiquitinationQTRYIKTSGNATVDH
CCEEEEECCCCCHHH
25.6621890473
260PhosphorylationNATVDHLSKYLAVRL
CCCHHHHHHHHHHHH
18.81-
261UbiquitinationATVDHLSKYLAVRLA
CCHHHHHHHHHHHHH
51.1223000965
262PhosphorylationTVDHLSKYLAVRLAL
CHHHHHHHHHHHHHH
9.1229759185
271UbiquitinationAVRLALEELRSKGES
HHHHHHHHHHHCCCC
50.7821890473
274UbiquitinationLALEELRSKGESNQM
HHHHHHHHCCCCCCC
58.6021890473
275UbiquitinationALEELRSKGESNQMN
HHHHHHHCCCCCCCC
61.33-
275AcetylationALEELRSKGESNQMN
HHHHHHHCCCCCCCC
61.3326051181
278O-linked_GlycosylationELRSKGESNQMNLDT
HHHHCCCCCCCCCCC
40.8223301498
320UbiquitinationLVSEKYWKVNKPMEL
EEEEEEEECCCCEEE
32.6121890473
323SumoylationEKYWKVNKPMELYYA
EEEEECCCCEEEEEC
49.05-
323UbiquitinationEKYWKVNKPMELYYA
EEEEECCCCEEEEEC
49.0521890473
323SumoylationEKYWKVNKPMELYYA
EEEEECCCCEEEEEC
49.0528112733
333UbiquitinationELYYAPTKEHK----
EEEECCCCCCC----
57.6832015554

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources
-KUbiquitinationE3 ubiquitin ligasePRC1O43663
PMID:22199232
-KUbiquitinationE3 ubiquitin ligaseBMI1P35226
PMID:16710298
-KUbiquitinationE3 ubiquitin ligaseRNF2Q99496
PMID:22910419
-KUbiquitinationE3 ubiquitin ligaseBMI1#RNF2P35226#Q99496
PMID:22199232

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of RING2_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of RING2_HUMAN !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
CBX4_HUMANCBX4physical
16169070
UBE2K_HUMANUBE2Kphysical
11513855
UB2D2_HUMANUBE2D2physical
11513855
UB2D1_HUMANUBE2D1physical
11513855
BMI1_HUMANBMI1physical
16359901
PCGF2_HUMANPCGF2physical
17936708
PRS6B_HUMANPSMC4physical
15773819
KMT2A_HUMANKMT2Aphysical
15960975
KAT8_HUMANKAT8physical
15960975
PO5F1_HUMANPOU5F1physical
18339675
H2A2C_HUMANHIST2H2ACphysical
15386022
PHB_HUMANPHBphysical
17873902
UBE3A_HUMANUBE3Aphysical
20351251
RING2_HUMANRNF2physical
20351251
H2A2C_HUMANHIST2H2ACphysical
20351251
UBP7_HUMANUSP7physical
20800574
H31T_HUMANHIST3H3physical
21596310
LMBL2_HUMANL3MBTL2physical
21596310
PCGF6_HUMANPCGF6physical
21596310
H2A2C_HUMANHIST2H2ACphysical
21772249
H2A2A_HUMANHIST2H2AA3physical
21772249
UB2D3_HUMANUBE2D3physical
21772249
PCGF1_HUMANPCGF1physical
22325352
PCGF2_HUMANPCGF2physical
22325352
PCGF3_HUMANPCGF3physical
22325352
BMI1_HUMANBMI1physical
22325352
PCGF5_HUMANPCGF5physical
22325352
PCGF6_HUMANPCGF6physical
22325352
RING1_HUMANRING1physical
22325352
RYBP_HUMANRYBPphysical
22325352
YAF2_HUMANYAF2physical
22325352
PHC1_HUMANPHC1physical
22325352
PHC2_HUMANPHC2physical
22325352
PHC3_HUMANPHC3physical
22325352
CBX2_HUMANCBX2physical
22325352
CBX4_HUMANCBX4physical
22325352
CBX6_HUMANCBX6physical
22325352
CBX8_HUMANCBX8physical
22325352
SCMH1_HUMANSCMH1physical
22325352
SCML1_HUMANSCML1physical
22325352
SCML2_HUMANSCML2physical
22325352
LMBL2_HUMANL3MBTL2physical
22325352
CBX3_HUMANCBX3physical
22325352
E2F6_HUMANE2F6physical
22325352
TFDP1_HUMANTFDP1physical
22325352
WDR5_HUMANWDR5physical
22325352
MGAP_HUMANMGAphysical
22325352
HDAC1_HUMANHDAC1physical
22325352
SKP1_HUMANSKP1physical
22325352
BCOR_HUMANBCORphysical
22325352
BCORL_HUMANBCORL1physical
22325352
KDM2B_HUMANKDM2Bphysical
22325352
UBP7_HUMANUSP7physical
22325352
AUTS2_HUMANAUTS2physical
22325352
FBRS_HUMANFBRSphysical
22325352
FBSL_HUMANFBRSL1physical
22325352
CSK21_HUMANCSNK2A1physical
22325352
CSK22_HUMANCSNK2A2physical
22325352
CSK2B_HUMANCSNK2Bphysical
22325352
BMI1_HUMANBMI1physical
21676867
H2AX_HUMANH2AFXphysical
21676867
PRGC1_HUMANPPARGC1Aphysical
22099309
PGP_HUMANPGPphysical
17088979
UB2D2_HUMANUBE2D2physical
22902369
PCGF2_HUMANPCGF2physical
22844243
CDN2A_HUMANCDKN2Aphysical
22910419
ARF_HUMANCDKN2Aphysical
22910419
RING2_HUMANRNF2physical
22910419
MAPK3_HUMANMAPKAPK3physical
15563468
BMI1_HUMANBMI1physical
15563468
PHC2_HUMANPHC2physical
15563468
UBC_HUMANUBCphysical
22493164
PCGF1_HUMANPCGF1physical
22493164
PCGF2_HUMANPCGF2physical
22493164
PCGF3_HUMANPCGF3physical
22493164
PCGF5_HUMANPCGF5physical
22493164
BMI1_HUMANBMI1physical
22493164
SIAH1_HUMANSIAH1physical
22493164
PCGF6_HUMANPCGF6physical
12167161
PHB2_HUMANPHB2physical
18629613
TFCP2_HUMANTFCP2physical
18629613
RING2_HUMANRNF2physical
18616292
UB2D3_HUMANUBE2D3physical
16714294
UB2D3_HUMANUBE2D3physical
21676867
UB2L3_HUMANUBE2L3physical
20351251
P53_HUMANTP53physical
22907436
P53_HUMANTP53physical
23318437
MDM2_HUMANMDM2physical
23318437
TYY1_HUMANYY1physical
16624538
CBX2_MOUSECbx2physical
12589020
CBX4_MOUSECbx4physical
12589020
BMI1_HUMANBMI1physical
12589020
PEG10_HUMANPEG10physical
12589020
RIR1_HUMANRRM1physical
24614341
UB2D3_HUMANUBE2D3physical
24614341
SNAI1_HUMANSNAI1physical
24903147
AMRA1_HUMANAMBRA1physical
24980959
UB2D3_HUMANUBE2D3physical
24980959
WASH1_HUMANWASH1physical
24980959
PK3C3_HUMANPIK3C3physical
24980959
BECN1_HUMANBECN1physical
24980959
BAKOR_HUMANATG14physical
24980959
H2A2C_HUMANHIST2H2ACphysical
16714294
H2A2C_HUMANHIST2H2ACphysical
16943429
UB2D3_HUMANUBE2D3physical
16943429
BMI1_HUMANBMI1physical
25355358
UB2D3_HUMANUBE2D3physical
25355358
NUCL_HUMANNCLphysical
24457600
NUMA1_HUMANNUMA1physical
24457600
CBX8_HUMANCBX8physical
24457600
PHC2_HUMANPHC2physical
24457600
HNRPU_HUMANHNRNPUphysical
24457600
RING1_HUMANRING1physical
24457600
ACTG_HUMANACTG1physical
24457600
PHC3_HUMANPHC3physical
24457600
DYHC1_HUMANDYNC1H1physical
24457600
TIF1B_HUMANTRIM28physical
24457600
MGAP_HUMANMGAphysical
24457600
LIMA1_HUMANLIMA1physical
24457600
RL4_HUMANRPL4physical
24457600
RL6_HUMANRPL6physical
24457600
SON_HUMANSONphysical
24457600
DDX5_HUMANDDX5physical
24457600
HNRPQ_HUMANSYNCRIPphysical
24457600
RS3A_HUMANRPS3Aphysical
24457600
BCOR_HUMANBCORphysical
24457600
PCGF2_HUMANPCGF2physical
24457600
HNRPC_HUMANHNRNPCphysical
24457600
CBX4_HUMANCBX4physical
24457600
RS2_HUMANRPS2physical
24457600
HNRPL_HUMANHNRNPLphysical
24457600
AT2A2_HUMANATP2A2physical
24457600
TPM3_HUMANTPM3physical
24457600
CHD4_HUMANCHD4physical
24457600
RL10_HUMANRPL10physical
24457600
ROA1_HUMANHNRNPA1physical
24457600
BMI1_HUMANBMI1physical
24457600
NOP58_HUMANNOP58physical
24457600
HNRPR_HUMANHNRNPRphysical
24457600
SCMH1_HUMANSCMH1physical
24457600
DHX9_HUMANDHX9physical
24457600
RS8_HUMANRPS8physical
24457600
RL7_HUMANRPL7physical
24457600
AIFM1_HUMANAIFM1physical
24457600
GCN1_HUMANGCN1L1physical
24457600
HNRL1_HUMANHNRNPUL1physical
24457600
CBX6_HUMANCBX6physical
24457600
MBB1A_HUMANMYBBP1Aphysical
24457600
ANDR_HUMANARphysical
24457600
RL7A_HUMANRPL7Aphysical
24457600
ACACA_HUMANACACAphysical
24457600
ILF3_HUMANILF3physical
24457600
KDM2B_HUMANKDM2Bphysical
24457600
CBX2_HUMANCBX2physical
24457600
TBB4B_HUMANTUBB4Bphysical
24457600
RS11_HUMANRPS11physical
24457600
HNRL2_HUMANHNRNPUL2physical
24457600
RL17_HUMANRPL17physical
24457600
U520_HUMANSNRNP200physical
24457600
SP16H_HUMANSUPT16Hphysical
24457600
RS24_HUMANRPS24physical
24457600
RL18A_HUMANRPL18Aphysical
24457600
RL10A_HUMANRPL10Aphysical
24457600
CBX7_HUMANCBX7physical
24457600
MYOME_HUMANPDE4DIPphysical
24457600
ATPB_HUMANATP5Bphysical
24457600
YBOX1_HUMANYBX1physical
24457600
TRI25_HUMANTRIM25physical
24457600
RL13A_HUMANRPL13Aphysical
24457600
CBX3_HUMANCBX3physical
24457600
RL28_HUMANRPL28physical
24457600
SF3B1_HUMANSF3B1physical
24457600
SF3B2_HUMANSF3B2physical
24457600
RS15A_HUMANRPS15Aphysical
24457600
LMBL2_HUMANL3MBTL2physical
24457600
RYBP_HUMANRYBPphysical
24457600
PDLI5_HUMANPDLIM5physical
24457600
TR150_HUMANTHRAP3physical
24457600
RL14_HUMANRPL14physical
24457600
SC16A_HUMANSEC16Aphysical
24457600
CSRP1_HUMANCSRP1physical
24457600
H10_HUMANH1F0physical
24457600
LC7L2_HUMANLUC7L2physical
24457600
EFTU_HUMANTUFMphysical
24457600
RL9_HUMANRPL9physical
24457600
DDX18_HUMANDDX18physical
24457600
CLH2_HUMANCLTCL1physical
24457600
SMC1A_HUMANSMC1Aphysical
24457600
DX39B_HUMANDDX39Bphysical
24457600
RL27A_HUMANRPL27Aphysical
24457600
HP1B3_HUMANHP1BP3physical
24457600
CHTOP_HUMANCHTOPphysical
24457600
ATD3A_HUMANATAD3Aphysical
24457600
ROA0_HUMANHNRNPA0physical
24457600
RACK1_HUMANGNB2L1physical
24457600
THOC4_HUMANALYREFphysical
24457600
RBP2_HUMANRANBP2physical
24457600
RL21_HUMANRPL21physical
24457600
RL3_HUMANRPL3physical
24457600
RL31_HUMANRPL31physical
24457600
RS13_HUMANRPS13physical
24457600
RL26_HUMANRPL26physical
24457600
DDX3X_HUMANDDX3Xphysical
24457600
SKP1_HUMANSKP1physical
24457600
COPA_HUMANCOPAphysical
24457600
ADNP_HUMANADNPphysical
24457600
RBM39_HUMANRBM39physical
24457600
PCGF6_HUMANPCGF6physical
24457600
RBMX_HUMANRBMXphysical
24457600
UBP7_HUMANUSP7physical
24457600
NOP2_HUMANNOP2physical
24457600
MRT4_HUMANMRTO4physical
24457600
FBRL_HUMANFBLphysical
24457600
RL34_HUMANRPL34physical
24457600
DKC1_HUMANDKC1physical
24457600
RBP56_HUMANTAF15physical
24457600
LMNB2_HUMANLMNB2physical
24457600
SMCA4_HUMANSMARCA4physical
24457600
ZCCHV_HUMANZC3HAV1physical
24457600
SCML2_HUMANSCML2physical
24457600
RL24_HUMANRPL24physical
24457600
RL32_HUMANRPL32physical
24457600
RL15_HUMANRPL15physical
24457600
RL27_HUMANRPL27physical
24457600
LAS1L_HUMANLAS1Lphysical
24457600
RBM14_HUMANRBM14physical
24457600
U2AF1_HUMANU2AF1physical
24457600
PRP8_HUMANPRPF8physical
24457600
EIF3A_HUMANEIF3Aphysical
24457600
YBOX3_HUMANYBX3physical
24457600
H2A3_HUMANHIST3H2Aphysical
24457600
TFR1_HUMANTFRCphysical
24457600
PABP4_HUMANPABPC4physical
24457600
LAD1_HUMANLAD1physical
24457600
M2OM_HUMANSLC25A11physical
24457600
SRSF1_HUMANSRSF1physical
24457600
DIC_HUMANSLC25A10physical
24457600
NOG1_HUMANGTPBP4physical
24457600
DSRAD_HUMANADARphysical
24457600
DHX30_HUMANDHX30physical
24457600
PCGF1_HUMANPCGF1physical
24457600
RL36_HUMANRPL36physical
24457600
RS26_HUMANRPS26physical
24457600
JCAD_HUMANKIAA1462physical
24457600
THOC2_HUMANTHOC2physical
24457600
RPB2_HUMANPOLR2Bphysical
24457600
SMCA5_HUMANSMARCA5physical
24457600
SYEP_HUMANEPRSphysical
24457600
EF2_HUMANEEF2physical
24457600
WDR43_HUMANWDR43physical
24457600
TBL1R_HUMANTBL1XR1physical
24457600
PTBP1_HUMANPTBP1physical
24457600
FUBP3_HUMANFUBP3physical
24457600
DDX56_HUMANDDX56physical
24457600
RL29_HUMANRPL29physical
24457600
MCM7_HUMANMCM7physical
24457600
LA_HUMANSSBphysical
24457600
SF3B3_HUMANSF3B3physical
24457600
ZFR_HUMANZFRphysical
24457600
ZC3H4_HUMANZC3H4physical
24457600
BMS1_HUMANBMS1physical
24457600
SMC3_HUMANSMC3physical
24457600
MYEF2_HUMANMYEF2physical
24457600
RL19_HUMANRPL19physical
24457600
DCAF7_HUMANDCAF7physical
24457600
SMD2_HUMANSNRPD2physical
24457600
DDX52_HUMANDDX52physical
24457600
EWS_HUMANEWSR1physical
24457600
RRP5_HUMANPDCD11physical
24457600
XRCC5_HUMANXRCC5physical
24457600
KS6A4_HUMANRPS6KA4physical
24457600
ZFP91_HUMANZFP91physical
24457600
HNRDL_HUMANHNRNPDLphysical
24457600
RL1D1_HUMANRSL1D1physical
24457600
AKAP9_HUMANAKAP9physical
24457600
RBM47_HUMANRBM47physical
24457600
RPN1_HUMANRPN1physical
24457600
PGAM5_HUMANPGAM5physical
24457600
BCLF1_HUMANBCLAF1physical
24457600
EF1D_HUMANEEF1Dphysical
24457600
PESC_HUMANPES1physical
24457600
SAMH1_HUMANSAMHD1physical
24457600
UIF_HUMANFYTTD1physical
24457600
BAZ1B_HUMANBAZ1Bphysical
24457600
FLNB_HUMANFLNBphysical
24457600
REPI1_HUMANREPIN1physical
24457600
HDAC2_HUMANHDAC2physical
24457600
RAD21_HUMANRAD21physical
24457600
SSRP1_HUMANSSRP1physical
24457600
KRR1_HUMANKRR1physical
24457600
EIF3B_HUMANEIF3Bphysical
24457600
AKAP8_HUMANAKAP8physical
24457600
AKP8L_HUMANAKAP8Lphysical
24457600
TYY1_HUMANYY1physical
24457600
SFXN1_HUMANSFXN1physical
24457600
RRP1_HUMANRRP1physical
24457600
H2AY_HUMANH2AFYphysical
24457600
RL23A_HUMANRPL23Aphysical
24457600
P5CR1_HUMANPYCR1physical
24457600
RBM8A_HUMANRBM8Aphysical
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RLA1_HUMANRPLP1physical
24457600
SPR1A_HUMANSPRR1Aphysical
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CYTSB_HUMANSPECC1physical
24457600
POGZ_HUMANPOGZphysical
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PDS5B_HUMANPDS5Bphysical
24457600
IQGA1_HUMANIQGAP1physical
24457600
CALR_HUMANCALRphysical
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RRP1B_HUMANRRP1Bphysical
24457600
COPG1_HUMANCOPG1physical
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RENT1_HUMANUPF1physical
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TCPG_HUMANCCT3physical
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TEX10_HUMANTEX10physical
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RU17_HUMANSNRNP70physical
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NUP93_HUMANNUP93physical
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VGF_HUMANVGFphysical
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ROA3_HUMANHNRNPA3physical
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IF2G_HUMANEIF2S3physical
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RUVB2_HUMANRUVBL2physical
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RAN_HUMANRANphysical
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ERH_HUMANERHphysical
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RS10_HUMANRPS10physical
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RS17_HUMANRPS17physical
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CSK2B_HUMANCSNK2Bphysical
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H2B3B_HUMANHIST3H2BBphysical
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CBX1_HUMANCBX1physical
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IF2A_HUMANEIF2S1physical
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TERA_HUMANVCPphysical
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YAF2_HUMANYAF2physical
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ZN326_HUMANZNF326physical
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SYNE1_HUMANSYNE1physical
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GTF2I_HUMANGTF2Iphysical
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DDX27_HUMANDDX27physical
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BOP1_HUMANBOP1physical
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SERA_HUMANPHGDHphysical
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TIM50_HUMANTIMM50physical
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HYEP_HUMANEPHX1physical
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KHDR1_HUMANKHDRBS1physical
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AFG32_HUMANAFG3L2physical
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HEAT1_HUMANHEATR1physical
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G3BP1_HUMANG3BP1physical
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RBM28_HUMANRBM28physical
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WDR46_HUMANWDR46physical
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TITIN_HUMANTTNphysical
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RRP12_HUMANRRP12physical
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LPPRC_HUMANLRPPRCphysical
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NU205_HUMANNUP205physical
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SART3_HUMANSART3physical
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RBM5_HUMANRBM5physical
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CPT1A_HUMANCPT1Aphysical
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LARP1_HUMANLARP1physical
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MCCA_HUMANMCCC1physical
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NCBP3_HUMANC17orf85physical
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UTP6_HUMANUTP6physical
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CALX_HUMANCANXphysical
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SMRD2_HUMANSMARCD2physical
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DDX50_HUMANDDX50physical
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ABCE1_HUMANABCE1physical
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FA60A_HUMANFAM60Aphysical
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STRBP_HUMANSTRBPphysical
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UTP15_HUMANUTP15physical
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EIF3D_HUMANEIF3Dphysical
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DHB12_HUMANHSD17B12physical
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RS7_HUMANRPS7physical
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H2A2B_HUMANHIST2H2ABphysical
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THEM6_HUMANTHEM6physical
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ELAV1_HUMANELAVL1physical
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RM11_HUMANMRPL11physical
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TF3C1_HUMANGTF3C1physical
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PWP2_HUMANPWP2physical
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P66B_HUMANGATAD2Bphysical
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NAT10_HUMANNAT10physical
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COPB_HUMANCOPB1physical
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NOL6_HUMANNOL6physical
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NDUS1_HUMANNDUFS1physical
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RCC1_HUMANRCC1physical
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NOL9_HUMANNOL9physical
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NOL11_HUMANNOL11physical
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RSMN_HUMANSNRPNphysical
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DNJA2_HUMANDNAJA2physical
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LDHB_HUMANLDHBphysical
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G3BP2_HUMANG3BP2physical
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ZN512_HUMANZNF512physical
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RPAB3_HUMANPOLR2Hphysical
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GHC1_HUMANSLC25A22physical
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SPR2A_HUMANSPRR2Aphysical
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IF4A3_HUMANEIF4A3physical
24457600
CG050_HUMANC7orf50physical
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ATPG_HUMANATP5C1physical
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CDK1_HUMANCDK1physical
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EIF3I_HUMANEIF3Iphysical
24457600
RBBP4_HUMANRBBP4physical
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AQR_HUMANAQRphysical
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TIAM2_HUMANTIAM2physical
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UBF1_HUMANUBTFphysical
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SMRC1_HUMANSMARCC1physical
24457600
LMO7_HUMANLMO7physical
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TIF1A_HUMANTRIM24physical
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ABCF1_HUMANABCF1physical
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CEBPZ_HUMANCEBPZphysical
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WDR12_HUMANWDR12physical
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PCGF5_HUMANPCGF5physical
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WIZ_HUMANWIZphysical
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AT5F1_HUMANATP5F1physical
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TRI26_HUMANTRIM26physical
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PUM3_HUMANKIAA0020physical
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UTP4_HUMANCIRH1Aphysical
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PCGF3_HUMANPCGF3physical
24457600
SRSF9_HUMANSRSF9physical
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U2AF2_HUMANU2AF2physical
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RRP7A_HUMANRRP7Aphysical
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TRAF2_HUMANTRAF2physical
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RUVB1_HUMANRUVBL1physical
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LYAR_HUMANLYARphysical
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PHB2_HUMANPHB2physical
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THOC6_HUMANTHOC6physical
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ATP5I_HUMANATP5Iphysical
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EMD_HUMANEMDphysical
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MYL6B_HUMANMYL6Bphysical
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NHP2_HUMANNHP2physical
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RT26_HUMANMRPS26physical
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RS19_HUMANRPS19physical
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ATS6_HUMANADAMTS6physical
24457600
ANK3_HUMANANK3physical
24457600
CNBP_HUMANCNBPphysical
24457600
MIC19_HUMANCHCHD3physical
24457600
RPA1_HUMANPOLR1Aphysical
24457600
HNRH3_HUMANHNRNPH3physical
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KLK2_HUMANKLK2physical
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NFXL1_HUMANNFXL1physical
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TIRR_HUMANNUDT16L1physical
24457600
SRSF3_HUMANSRSF3physical
24457600
TF65_HUMANRELAphysical
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PELP1_HUMANPELP1physical
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ZN638_HUMANZNF638physical
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UACA_HUMANUACAphysical
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PLAP_HUMANPLAAphysical
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TASOR_HUMANFAM208Aphysical
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IF2B_HUMANEIF2S2physical
24457600
RFC4_HUMANRFC4physical
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CAPR1_HUMANCAPRIN1physical
24457600
LARP7_HUMANLARP7physical
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DDX31_HUMANDDX31physical
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PYRG2_HUMANCTPS2physical
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TECR_HUMANTECRphysical
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PWP1_HUMANPWP1physical
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YTHD1_HUMANYTHDF1physical
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RAGP1_HUMANRANGAP1physical
24457600
EIF3L_HUMANEIF3Lphysical
24457600
FUBP2_HUMANKHSRPphysical
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H1X_HUMANH1FXphysical
24457600
RN222_HUMANRNF222physical
24457600
YTHD2_HUMANYTHDF2physical
24457600
ATLA3_HUMANATL3physical
24457600
TDRKH_HUMANTDRKHphysical
24457600
BIG3_HUMANKIAA1244physical
24457600
IGLL5_HUMANIGLL5physical
24457600
RPF2_HUMANRPF2physical
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MSI2H_HUMANMSI2physical
24457600
SUGP2_HUMANSUGP2physical
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PNO1_HUMANPNO1physical
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PPP6_HUMANPPP6Cphysical
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OCAD2_HUMANOCIAD2physical
24457600
RALY_HUMANRALYphysical
24457600
RED_HUMANIKphysical
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PFKAL_HUMANPFKLphysical
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ARPC4_HUMANARPC4physical
24457600
COPD_HUMANARCN1physical
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LPP_HUMANLPPphysical
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MTA1_HUMANMTA1physical
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PAR12_HUMANPARP12physical
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OTUB1_HUMANOTUB1physical
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MCM5_HUMANMCM5physical
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SMHD1_HUMANSMCHD1physical
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DPOD1_HUMANPOLD1physical
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BCORL_HUMANBCORL1physical
24457600
ZMYM3_HUMANZMYM3physical
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HYOU1_HUMANHYOU1physical
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U5S1_HUMANEFTUD2physical
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AT2C1_HUMANATP2C1physical
24457600
TRI56_HUMANTRIM56physical
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SMC4_HUMANSMC4physical
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TCPE_HUMANCCT5physical
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SPB1_HUMANFTSJ3physical
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FIP1_HUMANFIP1L1physical
24457600
SNUT1_HUMANSART1physical
24457600
REQU_HUMANDPF2physical
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NUP88_HUMANNUP88physical
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EHMT2_HUMANEHMT2physical
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DHE4_HUMANGLUD2physical
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PLMN_HUMANPLGphysical
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MOV10_HUMANMOV10physical
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ZN614_HUMANZNF614physical
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DDX51_HUMANDDX51physical
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CO052_HUMANC15orf52physical
24457600
MTA2_HUMANMTA2physical
24457600
PDIP3_HUMANPOLDIP3physical
24457600
UTP18_HUMANUTP18physical
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EIF3F_HUMANEIF3Fphysical
24457600
VIME_HUMANVIMphysical
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A4_HUMANAPPphysical
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ARAF_HUMANARAFphysical
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FXR2_HUMANFXR2physical
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SC11A_HUMANSEC11Aphysical
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FBRS_HUMANFBRSphysical
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ATPO_HUMANATP5Ophysical
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CSK21_HUMANCSNK2A1physical
24457600
RPAB1_HUMANPOLR2Ephysical
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PHF5A_HUMANPHF5Aphysical
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RCN1_HUMANRCN1physical
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SFXN2_HUMANSFXN2physical
24457600
ROAA_HUMANHNRNPABphysical
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MGN_HUMANMAGOHphysical
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MAGD2_HUMANMAGED2physical
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SMD1_HUMANSNRPD1physical
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ITM2A_HUMANITM2Aphysical
24457600
MIC27_HUMANAPOOLphysical
24457600
RL38_HUMANRPL38physical
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TBB2A_HUMANTUBB2Aphysical
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CIRBP_HUMANCIRBPphysical
24457600
XPO1_HUMANXPO1physical
24457600
XPOT_HUMANXPOTphysical
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HXB13_HUMANHOXB13physical
24457600
NH2L1_HUMANNHP2L1physical
24457600
SC22B_HUMANSEC22Bphysical
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RICTR_HUMANRICTORphysical
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WDR36_HUMANWDR36physical
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FBSL_HUMANFBRSL1physical
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NOP14_HUMANNOP14physical
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NU133_HUMANNUP133physical
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SMRC2_HUMANSMARCC2physical
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CND2_HUMANNCAPHphysical
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CADH1_HUMANCDH1physical
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ESRP1_HUMANESRP1physical
24457600
DC1I2_HUMANDYNC1I2physical
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MAGT1_HUMANMAGT1physical
24457600
KAT7_HUMANKAT7physical
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UHRF1_HUMANUHRF1physical
24457600
NOLC1_HUMANNOLC1physical
24457600
SPT5H_HUMANSUPT5Hphysical
24457600
TBL2_HUMANTBL2physical
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ACINU_HUMANACIN1physical
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CENPB_HUMANCENPBphysical
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COPB2_HUMANCOPB2physical
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RPA34_HUMANCD3EAPphysical
24457600
NCBP1_HUMANNCBP1physical
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NOC2L_HUMANNOC2Lphysical
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MPP10_HUMANMPHOSPH10physical
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CLPX_HUMANCLPXphysical
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SNW1_HUMANSNW1physical
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AMPL_HUMANLAP3physical
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SYF1_HUMANXAB2physical
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SNAA_HUMANNAPAphysical
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RPA49_HUMANPOLR1Ephysical
24457600
SEC13_HUMANSEC13physical
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RU2B_HUMANSNRPB2physical
24457600
BYST_HUMANBYSLphysical
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C1QBP_HUMANC1QBPphysical
24457600
NOB1_HUMANNOB1physical
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EPN4_HUMANCLINT1physical
24457600
RL22_HUMANRPL22physical
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PRP19_HUMANPRPF19physical
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ARL1_HUMANARL1physical
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MD2L1_HUMANMAD2L1physical
24457600
NSA2_HUMANNSA2physical
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VDAC3_HUMANVDAC3physical
24457600
SRS10_HUMANSRSF10physical
24457600
RT22_HUMANMRPS22physical
24457600
MK67I_HUMANNIFKphysical
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TRI14_HUMANTRIM14physical
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CISD1_HUMANCISD1physical
24457600
PURB_HUMANPURBphysical
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BACD3_HUMANKCTD10physical
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RL7L_HUMANRPL7L1physical
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COMT_HUMANCOMTphysical
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RS4Y1_HUMANRPS4Y1physical
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NDUA4_HUMANNDUFA4physical
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RS12_HUMANRPS12physical
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TBA1B_HUMANTUBA1Bphysical
24457600
CHD3_HUMANCHD3physical
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SYQ_HUMANQARSphysical
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GNAI2_HUMANGNAI2physical
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HDAC1_HUMANHDAC1physical
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IPO7_HUMANIPO7physical
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PHIP_HUMANPHIPphysical
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DHX33_HUMANDHX33physical
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PDXD1_HUMANPDXDC1physical
24457600
ZBT7B_HUMANZBTB7Bphysical
24457600
ABCB6_HUMANABCB6physical
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EEA1_HUMANEEA1physical
24457600
ZCHC8_HUMANZCCHC8physical
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DDX24_HUMANDDX24physical
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ESF1_HUMANESF1physical
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EFR3A_HUMANEFR3Aphysical
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SARM1_HUMANSARM1physical
24457600
ADDG_HUMANADD3physical
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SYMC_HUMANMARSphysical
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SYRC_HUMANRARSphysical
24457600
PP6R3_HUMANPPP6R3physical
24457600
F120A_HUMANFAM120Aphysical
24457600
SRP72_HUMANSRP72physical
24457600
ZN687_HUMANZNF687physical
24457600
C1TC_HUMANMTHFD1physical
24457600
XPO2_HUMANCSE1Lphysical
24457600
ZFY_HUMANZFYphysical
24457600
GNL3_HUMANGNL3physical
24457600
THOC1_HUMANTHOC1physical
24457600
NEB2_HUMANPPP1R9Bphysical
24457600
NOM1_HUMANNOM1physical
24457600
TRI41_HUMANTRIM41physical
24457600
PBIP1_HUMANPBXIP1physical
24457600
SYAM_HUMANAARS2physical
24457600
PDIA1_HUMANP4HBphysical
24457600
PKP2_HUMANPKP2physical
24457600
PTCD3_HUMANPTCD3physical
24457600
ACOT8_HUMANACOT8physical
24457600
LRCH1_HUMANLRCH1physical
24457600
ABCF3_HUMANABCF3physical
24457600
CACO2_HUMANCALCOCO2physical
24457600
ABCD3_HUMANABCD3physical
24457600
ADAM9_HUMANADAM9physical
24457600
SMCE1_HUMANSMARCE1physical
24457600
GLE1_HUMANGLE1physical
24457600
FKB11_HUMANFKBP11physical
24457600
GT251_HUMANCOLGALT1physical
24457600
SRP68_HUMANSRP68physical
24457600
CUL5_HUMANCUL5physical
24457600
DJC21_HUMANDNAJC21physical
24457600
LDHA_HUMANLDHAphysical
24457600
MFAP1_HUMANMFAP1physical
24457600
SF3A3_HUMANSF3A3physical
24457600
SESN3_HUMANSESN3physical
24457600
NDUAA_HUMANNDUFA10physical
24457600
NSF_HUMANNSFphysical
24457600
GLYR1_HUMANGLYR1physical
24457600
RRP8_HUMANRRP8physical
24457600
RN114_HUMANRNF114physical
24457600
CLN6_HUMANCLN6physical
24457600
S27A3_HUMANSLC27A3physical
24457600
ZC3HF_HUMANZC3H15physical
24457600
ZCCHL_HUMANZC3HAV1Lphysical
24457600
IMP3_HUMANIMP3physical
24457600
ZN346_HUMANZNF346physical
24457600
SMN_HUMANSMN1physical
24457600
SAP18_HUMANSAP18physical
24457600
SMD3_HUMANSNRPD3physical
24457600
CSRP2_HUMANCSRP2physical
24457600
TPIS_HUMANTPI1physical
24457600
TRA2A_HUMANTRA2Aphysical
24457600
AROS_HUMANRPS19BP1physical
24457600
RT07_HUMANMRPS7physical
24457600
GAR1_HUMANGAR1physical
24457600
RT17_HUMANMRPS17physical
24457600
AGK_HUMANAGKphysical
24457600
CDK13_HUMANCDK13physical
24457600
RAD50_HUMANRAD50physical
24457600
HAKAI_HUMANCBLL1physical
24457600
IF6_HUMANEIF6physical
24457600
TF3C4_HUMANGTF3C4physical
24457600
H14_HUMANHIST1H1Ephysical
24457600
IPO4_HUMANIPO4physical
24457600
IQEC1_HUMANIQSEC1physical
24457600
LC7L3_HUMANLUC7L3physical
24457600
SPF27_HUMANBCAS2physical
24457600
RER1_HUMANRER1physical
24457600
RADI_HUMANRDXphysical
24457600
RNPS1_HUMANRNPS1physical
24457600
ZC3HE_HUMANZC3H14physical
24457600
TDRD1_HUMANTDRD1physical
24457600
OGFR_HUMANOGFRphysical
24457600
GSLG1_HUMANGLG1physical
24457600
SENP3_HUMANSENP3physical
24457600
DMAP1_HUMANDMAP1physical
24457600
KDM1A_HUMANKDM1Aphysical
24457600
PRS7_HUMANPSMC2physical
24457600
TOP1_HUMANTOP1physical
24457600
SF3B4_HUMANSF3B4physical
24457600
ZN787_HUMANZNF787physical
24457600
CRNL1_HUMANCRNKL1physical
24457600
SYTC_HUMANTARSphysical
24457600
KI20A_HUMANKIF20Aphysical
24457600
MMS19_HUMANMMS19physical
24457600
TMX3_HUMANTMX3physical
24457600
RFA1_HUMANRPA1physical
24457600
PTSS1_HUMANPTDSS1physical
24457600
FAF2_HUMANFAF2physical
24457600
THOC5_HUMANTHOC5physical
24457600
ZN740_HUMANZNF740physical
24457600
LRRF1_HUMANLRRFIP1physical
24457600
ZN363_HUMANRCHY1physical
24457600
CPSF5_HUMANNUDT21physical
24457600
RPB7_HUMANPOLR2Gphysical
24457600
DAZP1_HUMANDAZAP1physical
24457600
NGDN_HUMANNGDNphysical
24457600
ODPB_HUMANPDHBphysical
24457600
LYRIC_HUMANMTDHphysical
24457600
TBAL3_HUMANTUBAL3physical
24457600
TMEDA_HUMANTMED10physical
24457600
RM48_HUMANMRPL48physical
24457600
NOL7_HUMANNOL7physical
24457600
MIRO2_HUMANRHOT2physical
24457600
USMG5_HUMANUSMG5physical
24457600
H12_HUMANHIST1H1Cphysical
24457600
H13_HUMANHIST1H1Dphysical
24457600
H33_HUMANH3F3Aphysical
24457600
PHB_HUMANPHBphysical
24457600
SF3A1_HUMANSF3A1physical
24457600
CXXC1_HUMANCXXC1physical
24457600
ZF64A_HUMANZFP64physical
24457600
ZF64B_HUMANZFP64physical
24457600
NOC3L_HUMANNOC3Lphysical
24457600
PSD12_HUMANPSMD12physical
24457600
TIDC1_HUMANTIMMDC1physical
24457600
QPCTL_HUMANQPCTLphysical
24457600
AT2B1_HUMANATP2B1physical
24457600
MTCH2_HUMANMTCH2physical
24457600
PSA6_HUMANPSMA6physical
24457600
RSSA_HUMANRPSAphysical
24457600
BRI3B_HUMANBRI3BPphysical
24457600
NUBPL_HUMANNUBPLphysical
24457600
RCL1_HUMANRCL1physical
24457600
LCLT1_HUMANLCLAT1physical
24457600
SNRPA_HUMANSNRPAphysical
24457600
NDUA9_HUMANNDUFA9physical
24457600
RT21_HUMANMRPS21physical
24457600
NDK3_HUMANNME3physical
24457600
RAB10_HUMANRAB10physical
24457600
RS15_HUMANRPS15physical
24457600
H2A2A_HUMANHIST2H2AA3physical
24457600
UB2D3_HUMANUBE2D3physical
24457600
AUTS2_HUMANAUTS2physical
25519132
PCGF5_HUMANPCGF5physical
25519132
H2A2C_HUMANHIST2H2ACphysical
25519132
UB2D3_HUMANUBE2D3physical
25519132
UBP7_HUMANUSP7physical
25605328
SCML2_HUMANSCML2physical
25605328
BMI1_HUMANBMI1physical
26496610
PHC1_HUMANPHC1physical
26496610
PHC2_HUMANPHC2physical
26496610
TRI27_HUMANTRIM27physical
26496610
RING1_HUMANRING1physical
26496610
RLA0_HUMANRPLP0physical
26496610
TOP2A_HUMANTOP2Aphysical
26496610
UBP7_HUMANUSP7physical
26496610
CBX4_HUMANCBX4physical
26496610
YAF2_HUMANYAF2physical
26496610
SCML2_HUMANSCML2physical
26496610
WDR6_HUMANWDR6physical
26496610
MGAP_HUMANMGAphysical
26496610
RYBP_HUMANRYBPphysical
26496610
RL1D1_HUMANRSL1D1physical
26496610
BCOR_HUMANBCORphysical
26496610
AKIP1_HUMANAKIP1physical
26496610
CBX8_HUMANCBX8physical
26496610
FBRS_HUMANFBRSphysical
26496610
PHC3_HUMANPHC3physical
26496610
ACTL8_HUMANACTL8physical
26496610
PCGF6_HUMANPCGF6physical
26496610
KDM2B_HUMANKDM2Bphysical
26496610
CBX2_HUMANCBX2physical
26496610
PCGF1_HUMANPCGF1physical
26496610
H2A2C_HUMANHIST2H2ACphysical
25470042
PCGF1_HUMANPCGF1physical
26151332
PCGF2_HUMANPCGF2physical
26151332
PCGF3_HUMANPCGF3physical
26151332
BMI1_HUMANBMI1physical
26151332
PCGF5_HUMANPCGF5physical
26151332
PCGF6_HUMANPCGF6physical
26151332
KDM6A_HUMANKDM6Aphysical
26450788
SIK1_HUMANSIK1physical
27911266
MARF1_HUMANKIAA0430physical
27173435
UB2E1_HUMANUBE2E1physical
28073915
BMI1_HUMANBMI1physical
28073915
RING2_HUMANRNF2physical
28073915

Drug and Disease Associations
Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of RING2_HUMAN

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Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach.";
Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.;
Anal. Chem. 81:4493-4501(2009).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-168, AND MASSSPECTROMETRY.
"Evaluation of the low-specificity protease elastase for large-scalephosphoproteome analysis.";
Wang B., Malik R., Nigg E.A., Korner R.;
Anal. Chem. 80:9526-9533(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-203, AND MASSSPECTROMETRY.
"Global, in vivo, and site-specific phosphorylation dynamics insignaling networks.";
Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P.,Mann M.;
Cell 127:635-648(2006).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-168, AND MASSSPECTROMETRY.

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