dbPTM

NUBPL_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	NUBPL_HUMAN
UniProt AC	Q8TB37
Protein Name	Iron-sulfur protein NUBPL
Gene Name	NUBPL
Organism	Homo sapiens (Human).
Sequence Length	319
Subcellular Localization	Mitochondrion .
Protein Description	Required for the assembly of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I). May deliver of one or more Fe-S clusters to complex I subunits..
Protein Sequence	MGIWQRLLLFGGVSLRAGGGATAPLGGSRAMVCGRQLSGAGSETLKQRRTQIMSRGLPKQKPIEGVKQVIVVASGKGGVGKSTTAVNLALALAANDSSKAIGLLDVDVYGPSVPKMMNLKGNPELSQSNLMRPLLNYGIACMSMGFLVEESEPVVWRGLMVMSAIEKLLRQVDWGQLDYLVVDMPPGTGDVQLSVSQNIPITGAVIVSTPQDIALMDAHKGAEMFRRVHVPVLGLVQNMSVFQCPKCKHKTHIFGADGARKLAQTLGLEVLGDIPLHLNIREASDTGQPIVFSQPESDEAKAYLRIAVEVVRRLPSPSE

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
50	Phosphorylation	ETLKQRRTQIMSRGL HHHHHHHHHHHHCCC	25.33	30622161
61	Methylation	SRGLPKQKPIEGVKQ HCCCCCCCCCCCCCE	54.83	-
82	Phosphorylation	GKGGVGKSTTAVNLA CCCCCCHHHHHHHHH	25.68	23403867
83	Phosphorylation	KGGVGKSTTAVNLAL CCCCCHHHHHHHHHH	23.43	23403867
84	Phosphorylation	GGVGKSTTAVNLALA CCCCHHHHHHHHHHH	35.38	23403867
98	Phosphorylation	ALAANDSSKAIGLLD HHHHCCCCCCCCCCE	29.04	23403867
109	Phosphorylation	GLLDVDVYGPSVPKM CCCEEEECCCCCCHH	20.89	23403867
112	Phosphorylation	DVDVYGPSVPKMMNL EEEECCCCCCHHCCC	46.84	23403867
240	Phosphorylation	LGLVQNMSVFQCPKC HHHCCCCEEEECCCC	27.59	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of NUBPL_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of NUBPL_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of NUBPL_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
MTUS2_HUMAN	MTUS2	physical	24722188

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of NUBPL_HUMAN

Related Literatures of Post-Translational Modification