ZN614_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZN614_HUMAN
• UniProt AC: Q8N883
• Protein Name: Zinc finger protein 614
• Gene Name: ZNF614
• Organism: Homo sapiens (Human).
• Sequence Length: 585
• Subcellular Localization: Nucleus .
• Protein Description: May be involved in transcriptional regulation..
• Protein Sequence: MIKTQESLTLEDVAVEFSWEEWQLLDTAQKNLYRDVMVENYNHLVSLGYQTSKPDVLSKLAHGQEPWTTDAKIQNKNCPGIGKVDSHLQEHSPNQRLLKSVQQCNGQNTLRNIVHLSKTHFPIVQNHDTFDLYRKNLKSSLSLINQKRRHGINNPVEFIGGEKTLLHGKHERTHTKTRFSENAKCIHTKFQVFKHQRTQKIEKPHACIECEQTFLRKSQLIYHENICIQENPGSGQCEKLSRSVLFTKHLKTNTTDKICIPNEYRKGSTVKSSLITHQQTHTEEKSYMCSECGKGFTMKRYLIAHQRTHSGEKPYVCKECGKGFTVKSNLIVHQRTHTGEKPYICSECGKGFTMKRYLVVHQRTHTGEKPYMCSECGKGFTVKSNLIVHQRSHTGEKSYICSECGKGFTVKRTLVIHQRTHTGEKSYICNECGKGFTTKRTLIIHQRTHTGEKPYECNECGKAFSQKICLIQHERCHTGKTPFVCTECGKSYSHKYGLITHQRIHTGEKPYECNECGKAFTTKSVLNVHQRTHTGERPYGCSDCEKAFSHLSNLVKHKKMHTREMGRISQVENSCNGESQLLPYK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
72	Ubiquitination	EPWTTDAKIQNKNCP CCCCCCHHHCCCCCC	47.86	29967540
83	Ubiquitination	KNCPGIGKVDSHLQE CCCCCCCCCCHHHHH	40.73	29967540
92	Phosphorylation	DSHLQEHSPNQRLLK CHHHHHCCCCHHHHH	25.45	20873877
99	Ubiquitination	SPNQRLLKSVQQCNG CCCHHHHHHHHHCCC	53.85	29967540
109	Phosphorylation	QQCNGQNTLRNIVHL HHCCCCCHHHHHHHH	21.14	-
147	Ubiquitination	SLSLINQKRRHGINN HHHHHHHHHHCCCCC	47.08	29967540
273	Phosphorylation	KGSTVKSSLITHQQT CCCCCHHHHHCCCCC	20.34	28348404
276	Phosphorylation	TVKSSLITHQQTHTE CCHHHHHCCCCCCCC	20.94	28348404
280	Phosphorylation	SLITHQQTHTEEKSY HHHCCCCCCCCCCCE	24.97	28348404
282	Phosphorylation	ITHQQTHTEEKSYMC HCCCCCCCCCCCEEC	49.58	28348404
297	Phosphorylation	SECGKGFTMKRYLIA CCCCCCCEEEEHHEE	30.37	23532336
325	Phosphorylation	KECGKGFTVKSNLIV CCCCCCEEEECCEEE	35.38	-
328	Phosphorylation	GKGFTVKSNLIVHQR CCCEEEECCEEEEEC	32.31	-
336	Phosphorylation	NLIVHQRTHTGEKPY CEEEEECCCCCCCCE	19.74	-
338	Phosphorylation	IVHQRTHTGEKPYIC EEEECCCCCCCCEEE	46.56	-
343	Phosphorylation	THTGEKPYICSECGK CCCCCCCEEECCCCC	26.15	-
353	Phosphorylation	SECGKGFTMKRYLVV CCCCCCEEEEEEEEE	30.37	23532336
357	Phosphorylation	KGFTMKRYLVVHQRT CCEEEEEEEEEEECC	9.79	22461510
364	Phosphorylation	YLVVHQRTHTGEKPY EEEEEECCCCCCCCE	19.74	22461510
366	Phosphorylation	VVHQRTHTGEKPYMC EEEECCCCCCCCEEC	46.56	22461510
381	Phosphorylation	SECGKGFTVKSNLIV CCCCCCEEEECCEEE	35.38	-
384	Phosphorylation	GKGFTVKSNLIVHQR CCCEEEECCEEEEEC	32.31	-
392	Phosphorylation	NLIVHQRSHTGEKSY CEEEEECCCCCCCEE	20.87	-
394	Phosphorylation	IVHQRSHTGEKSYIC EEEECCCCCCCEEEE	48.56	-
420	Phosphorylation	TLVIHQRTHTGEKSY EEEEEECCCCCCCEE	19.74	-
422	Phosphorylation	VIHQRTHTGEKSYIC EEEECCCCCCCEEEC	46.56	-
425	Acetylation	QRTHTGEKSYICNEC ECCCCCCCEEECCCC	50.32	7428845
448	Phosphorylation	TLIIHQRTHTGEKPY EEEEEECCCCCCCCC	19.74	28348404
450	Phosphorylation	IIHQRTHTGEKPYEC EEEECCCCCCCCCCC	46.56	29496963
453	Acetylation	QRTHTGEKPYECNEC ECCCCCCCCCCCCCC	55.00	7428853
453	Ubiquitination	QRTHTGEKPYECNEC ECCCCCCCCCCCCCC	55.00	-
455	Phosphorylation	THTGEKPYECNECGK CCCCCCCCCCCCCHH	44.15	-
506	Phosphorylation	ITHQRIHTGEKPYEC EECCEEECCCCCEEC	44.67	28152594
509	Ubiquitination	QRIHTGEKPYECNEC CEEECCCCCEECCCC	55.00	-
511	Phosphorylation	IHTGEKPYECNECGK EECCCCCEECCCCCC	44.15	28152594
524	Phosphorylation	GKAFTTKSVLNVHQR CCEEECHHHEEEECC	29.73	30622161
584	Phosphorylation	GESQLLPYK------ CCCCCCCCC------	29.33	17929957

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZN614_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZN614_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZN614_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
FAM9B_HUMAN	FAM9B	physical	25416956

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.