dbPTM

BMI1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	BMI1_HUMAN
UniProt AC	P35226
Protein Name	Polycomb complex protein BMI-1
Gene Name	BMI1
Organism	Homo sapiens (Human).
Sequence Length	326
Subcellular Localization	Nucleus . Cytoplasm .
Protein Description	Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. [PubMed: 15386022]
Protein Sequence	MHRTTRIKITELNPHLMCVLCGGYFIDATTIIECLHSFCKTCIVRYLETSKYCPICDVQVHKTRPLLNIRSDKTLQDIVYKLVPGLFKNEMKRRRDFYAAHPSADAANGSNEDRGEVADEDKRIITDDEIISLSIEFFDQNRLDRKVNKDKEKSKEEVNDKRYLRCPAAMTVMHLRKFLRSKMDIPNTFQIDVMYEEEPLKDYYTLMDIAYIYTWRRNGPLPLKYRVRPTCKRMKISHQRDGLTNAGELESDSGSDKANSPAGGIPSTSSCLPSPSTPVQSPHPQFPHISSTMNGTSNSPSGNHQSSFANRPRKSSVNGSSATSSG

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
51	Acetylation	VRYLETSKYCPICDV HHHHHHCCCCCCCCE	59.29	26051181
51	Ubiquitination	VRYLETSKYCPICDV HHHHHHCCCCCCCCE	59.29	32015554
62	Ubiquitination	ICDVQVHKTRPLLNI CCCEEEEECCCCCCC	47.58	PubMed
73	Ubiquitination	LLNIRSDKTLQDIVY CCCCCCCCCHHHHHH	53.00	21890473
81	Ubiquitination	TLQDIVYKLVPGLFK CHHHHHHHHCCCCCH	31.92	33845483
88	Sumoylation	KLVPGLFKNEMKRRR HHCCCCCHHHHHHHH	57.97	-
88	Ubiquitination	KLVPGLFKNEMKRRR HHCCCCCHHHHHHHH	57.97	32015554
88	Sumoylation	KLVPGLFKNEMKRRR HHCCCCCHHHHHHHH	57.97	-
103	Phosphorylation	DFYAAHPSADAANGS CHHHHCCCCCCCCCC	28.99	27732954
110	Phosphorylation	SADAANGSNEDRGEV CCCCCCCCCCCCCCC	36.53	30624053
114	Methylation	ANGSNEDRGEVADED CCCCCCCCCCCCCCC	36.67	-
122	Ubiquitination	GEVADEDKRIITDDE CCCCCCCCCCCCCHH	43.37	24816145
151	Acetylation	DRKVNKDKEKSKEEV HHCCCCCHHHCHHHH	69.52	7987715
153	Ubiquitination	KVNKDKEKSKEEVND CCCCCHHHCHHHHCC	72.99	24816145
203	Phosphorylation	EEEPLKDYYTLMDIA ECCCCCCCEEHHHHH	9.21	26657352
204	Phosphorylation	EEPLKDYYTLMDIAY CCCCCCCEEHHHHHH	11.97	-
216	Ubiquitination	IAYIYTWRRNGPLPL HHHHHHCCCCCCCCC	17.87	-
224	Ubiquitination	RNGPLPLKYRVRPTC CCCCCCCEEEECCCC	29.13	-
224	Acetylation	RNGPLPLKYRVRPTC CCCCCCCEEEECCCC	29.13	26051181
231	Sumoylation	KYRVRPTCKRMKISH EEEECCCCCCCCCCC	2.66	-
244	Phosphorylation	SHQRDGLTNAGELES CCCCCCCCCCHHCCC	28.66	23403867
251	Phosphorylation	TNAGELESDSGSDKA CCCHHCCCCCCCCCC	50.10	30266825
253	Phosphorylation	AGELESDSGSDKANS CHHCCCCCCCCCCCC	49.85	30266825
255	Phosphorylation	ELESDSGSDKANSPA HCCCCCCCCCCCCCC	39.63	29255136
255	O-linked_Glycosylation	ELESDSGSDKANSPA HCCCCCCCCCCCCCC	39.63	29485866
257	Methylation	ESDSGSDKANSPAGG CCCCCCCCCCCCCCC	51.68	-
260	Phosphorylation	SGSDKANSPAGGIPS CCCCCCCCCCCCCCC	22.46	-
269	Phosphorylation	AGGIPSTSSCLPSPS CCCCCCCCCCCCCCC	24.32	-
274	Phosphorylation	STSSCLPSPSTPVQS CCCCCCCCCCCCCCC	20.66	-
276	Phosphorylation	SSCLPSPSTPVQSPH CCCCCCCCCCCCCCC	50.08	-
277	Phosphorylation	SCLPSPSTPVQSPHP CCCCCCCCCCCCCCC	30.75	-
281	Phosphorylation	SPSTPVQSPHPQFPH CCCCCCCCCCCCCCC	25.96	-
290	Phosphorylation	HPQFPHISSTMNGTS CCCCCCCCCCCCCCC	19.40	-
315	Phosphorylation	FANRPRKSSVNGSSA CCCCCCCCCCCCCCC	40.58	26329039
316	Phosphorylation	ANRPRKSSVNGSSAT CCCCCCCCCCCCCCC	23.72	26329039
320	Phosphorylation	RKSSVNGSSATSSG- CCCCCCCCCCCCCC-	16.17	28857561
321	Phosphorylation	KSSVNGSSATSSG-- CCCCCCCCCCCCC--	36.64	26329039
323	Phosphorylation	SVNGSSATSSG---- CCCCCCCCCCC----	25.93	26329039
324	Phosphorylation	VNGSSATSSG----- CCCCCCCCCC-----	32.55	26329039
325	Phosphorylation	NGSSATSSG------ CCCCCCCCC------	44.14	26329039
367	Ubiquitination	------------------------------------------------ ------------------------------------------------		-
387	Phosphorylation	-------------------------------------------------------------------- --------------------------------------------------------------------		-
394	Phosphorylation	--------------------------------------------------------------------------- ---------------------------------------------------------------------------		27251275
396	Phosphorylation	----------------------------------------------------------------------------- -----------------------------------------------------------------------------		27251275
398	Phosphorylation	------------------------------------------------------------------------------- -------------------------------------------------------------------------------		27251275
458	Phosphorylation	------------------------------------------------------------------------------------------------------------------------------------------- -------------------------------------------------------------------------------------------------------------------------------------------		-
459	Phosphorylation	-------------------------------------------------------------------------------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------		24719451

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
110	S	Phosphorylation	Kinase	CSNK2A1	P68400	GPS
316	S	Phosphorylation	Kinase	AKT1	P31749	PSP
-	K	Ubiquitination	E3 ubiquitin ligase	BTRC	Q9Y297	PMID:24658274
-	K	Ubiquitination	E3 ubiquitin ligase	SPOP	O43791	PMID:15897469

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of BMI1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of BMI1_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
RING1_HUMAN	RING1	physical	9199346
CBX4_HUMAN	CBX4	physical	9199346
PHC1_HUMAN	PHC1	physical	9199346
BMI1_HUMAN	BMI1	physical	9858531
PHC1_HUMAN	PHC1	physical	9121482
PHC2_HUMAN	PHC2	physical	9121482
E2F6_HUMAN	E2F6	physical	11171983
ZBT16_HUMAN	ZBTB16	physical	12408802
MIC60_HUMAN	IMMT	physical	16169070
CE126_HUMAN	KIAA1377	physical	16169070
PTN_HUMAN	PTN	physical	16169070
KAT5_HUMAN	KAT5	physical	16169070
LRIF1_HUMAN	LRIF1	physical	16169070
RING2_HUMAN	RNF2	physical	16359901
RING1_HUMAN	RING1	physical	16359901
CBX4_HUMAN	CBX4	physical	18453536
RING2_HUMAN	RNF2	physical	17157253
RING2_HUMAN	RNF2	physical	16714294
H2A2C_HUMAN	HIST2H2AC	physical	16714294
PHC1_HUMAN	PHC1	physical	19636380
PHC3_HUMAN	PHC3	physical	19636380
PHC2_HUMAN	PHC2	physical	19636380
RING2_HUMAN	RNF2	physical	19636380
CBX4_HUMAN	CBX4	physical	19636380
CBX2_HUMAN	CBX2	physical	19636380
RING1_HUMAN	RING1	physical	19636380
CBX8_HUMAN	CBX8	physical	19636380
FOXS1_HUMAN	FOXS1	physical	20211142
RING1_HUMAN	RING1	physical	16751658
RING2_HUMAN	RNF2	physical	16751658
XRCC5_HUMAN	XRCC5	physical	20668194
PARP1_HUMAN	PARP1	physical	20668194
PRKDC_HUMAN	PRKDC	physical	20668194
UBP7_HUMAN	USP7	physical	20601937
UBP11_HUMAN	USP11	physical	20601937
FBW1A_HUMAN	BTRC	physical	21430439
H2A2C_HUMAN	HIST2H2AC	physical	21772249
H2A2A_HUMAN	HIST2H2AA3	physical	21772249
UB2D3_HUMAN	UBE2D3	physical	21772249
RING2_HUMAN	RNF2	physical	22325352
RING1_HUMAN	RING1	physical	22325352
RYBP_HUMAN	RYBP	physical	22325352
YAF2_HUMAN	YAF2	physical	22325352
PHC1_HUMAN	PHC1	physical	22325352
PHC2_HUMAN	PHC2	physical	22325352
PHC3_HUMAN	PHC3	physical	22325352
CBX2_HUMAN	CBX2	physical	22325352
CBX4_HUMAN	CBX4	physical	22325352
CBX6_HUMAN	CBX6	physical	22325352
CBX8_HUMAN	CBX8	physical	22325352
SCMH1_HUMAN	SCMH1	physical	22325352
BMI1_HUMAN	BMI1	physical	22325352
ATM_HUMAN	ATM	physical	21676867
RING2_HUMAN	RNF2	physical	21676867
H2AX_HUMAN	H2AFX	physical	21676867
ZBT16_HUMAN	ZBTB16	physical	19451220
SPYA_HUMAN	AGXT	physical	19451220
TUSC3_HUMAN	TUSC3	physical	19451220
RING1_HUMAN	RING1	physical	19451220
MAPK3_HUMAN	MAPKAPK3	physical	15563468
PTEN_HUMAN	PTEN	physical	19903340
UB2D3_HUMAN	UBE2D3	physical	16714294
P53_HUMAN	TP53	physical	22907436
RING1_HUMAN	RING1	physical	22897849
PHC1_HUMAN	PHC1	physical	23523425
VPS11_HUMAN	VPS11	physical	22493164
RN114_HUMAN	RNF114	physical	22493164
SOCS2_HUMAN	SOCS2	physical	21988832
RIR1_HUMAN	RRM1	physical	24614341
UB2D3_HUMAN	UBE2D3	physical	24614341
P53_HUMAN	TP53	physical	24039897
PHC2_HUMAN	PHC2	physical	25416956
RING1_HUMAN	RING1	physical	25416956
NDEL1_HUMAN	NDEL1	physical	25416956
YLPM1_HUMAN	YLPM1	physical	24457600
ILF3_HUMAN	ILF3	physical	24457600
RBP56_HUMAN	TAF15	physical	24457600
TDRD1_HUMAN	TDRD1	physical	24457600
RENT1_HUMAN	UPF1	physical	24457600
DSRAD_HUMAN	ADAR	physical	24457600
TASOR_HUMAN	FAM208A	physical	24457600
SON_HUMAN	SON	physical	24457600
FUS_HUMAN	FUS	physical	24457600
TR150_HUMAN	THRAP3	physical	24457600
ZN638_HUMAN	ZNF638	physical	24457600
NUMA1_HUMAN	NUMA1	physical	24457600
EWS_HUMAN	EWSR1	physical	24457600
PLEC_HUMAN	PLEC	physical	24457600
F120A_HUMAN	FAM120A	physical	24457600
PABP4_HUMAN	PABPC4	physical	24457600
U5S1_HUMAN	EFTUD2	physical	24457600
ILF2_HUMAN	ILF2	physical	24457600
NCBP1_HUMAN	NCBP1	physical	24457600
ELAV1_HUMAN	ELAVL1	physical	24457600
TRA2A_HUMAN	TRA2A	physical	24457600
NUCL_HUMAN	NCL	physical	24457600
BCLF1_HUMAN	BCLAF1	physical	24457600
HELZ2_HUMAN	HELZ2	physical	24457600
SCAFB_HUMAN	SCAF11	physical	24457600
SAFB2_HUMAN	SAFB2	physical	24457600
SLTM_HUMAN	SLTM	physical	24457600
CBX8_HUMAN	CBX8	physical	24457600
SRRT_HUMAN	SRRT	physical	24457600
IF4A3_HUMAN	EIF4A3	physical	24457600
TIF1B_HUMAN	TRIM28	physical	24457600
NCOA5_HUMAN	NCOA5	physical	24457600
YBOX1_HUMAN	YBX1	physical	24457600
KHDR1_HUMAN	KHDRBS1	physical	24457600
ACTG_HUMAN	ACTG1	physical	24457600
RING1_HUMAN	RING1	physical	24457600
DAZP1_HUMAN	DAZAP1	physical	24457600
DYHC1_HUMAN	DYNC1H1	physical	24457600
YBOX3_HUMAN	YBX3	physical	24457600
ACINU_HUMAN	ACIN1	physical	24457600
RTCB_HUMAN	RTCB	physical	24457600
RALY_HUMAN	RALY	physical	24457600
CHERP_HUMAN	CHERP	physical	24457600
SUGP2_HUMAN	SUGP2	physical	24457600
PKP1_HUMAN	PKP1	physical	24457600
PPHLN_HUMAN	PPHLN1	physical	24457600
KHDR3_HUMAN	KHDRBS3	physical	24457600
AQR_HUMAN	AQR	physical	24457600
CN166_HUMAN	C14orf166	physical	24457600
WDR33_HUMAN	WDR33	physical	24457600
PTBP1_HUMAN	PTBP1	physical	24457600
MSI2H_HUMAN	MSI2	physical	24457600
ATX2_HUMAN	ATXN2	physical	24457600
CAPR1_HUMAN	CAPRIN1	physical	24457600
RNC_HUMAN	DROSHA	physical	24457600
ZN326_HUMAN	ZNF326	physical	24457600
GEMI5_HUMAN	GEMIN5	physical	24457600
SPT6H_HUMAN	SUPT6H	physical	24457600
PHC2_HUMAN	PHC2	physical	24457600
MGN_HUMAN	MAGOH	physical	24457600
PUM2_HUMAN	PUM2	physical	24457600
CIRBP_HUMAN	CIRBP	physical	24457600
SMCA4_HUMAN	SMARCA4	physical	24457600
AKAP8_HUMAN	AKAP8	physical	24457600
H2AY_HUMAN	H2AFY	physical	24457600
SK2L2_HUMAN	SKIV2L2	physical	24457600
ZCCHV_HUMAN	ZC3HAV1	physical	24457600
TADBP_HUMAN	TARDBP	physical	24457600
TIRR_HUMAN	NUDT16L1	physical	24457600
H2B1B_HUMAN	HIST1H2BB	physical	24457600
PRC2A_HUMAN	PRRC2A	physical	24457600
G3BP1_HUMAN	G3BP1	physical	24457600
SMU1_HUMAN	SMU1	physical	24457600
H2B1D_HUMAN	HIST1H2BD	physical	24457600
H2B1C_HUMAN	HIST1H2BD	physical	24457600
G3BP2_HUMAN	G3BP2	physical	24457600
CIZ1_HUMAN	CIZ1	physical	24457600
MBB1A_HUMAN	MYBBP1A	physical	24457600
MINT_HUMAN	SPEN	physical	24457600
KLHL8_HUMAN	KLHL8	physical	24457600
SMCA2_HUMAN	SMARCA2	physical	24457600
SMN_HUMAN	SMN1	physical	24457600
PSPC1_HUMAN	PSPC1	physical	24457600
PAIP1_HUMAN	PAIP1	physical	24457600
ERH_HUMAN	ERH	physical	24457600
MYEF2_HUMAN	MYEF2	physical	24457600
YTDC1_HUMAN	YTHDC1	physical	24457600
NOP58_HUMAN	NOP58	physical	24457600
ZCHC8_HUMAN	ZCCHC8	physical	24457600
YTHD1_HUMAN	YTHDF1	physical	24457600
TIAR_HUMAN	TIAL1	physical	24457600
AKP8L_HUMAN	AKAP8L	physical	24457600
ACACA_HUMAN	ACACA	physical	24457600
RACK1_HUMAN	GNB2L1	physical	24457600
RING2_HUMAN	RNF2	physical	24457600
CHD4_HUMAN	CHD4	physical	24457600
PHF3_HUMAN	PHF3	physical	24457600
LIMA1_HUMAN	LIMA1	physical	24457600
NCBP3_HUMAN	C17orf85	physical	24457600
ZC3HD_HUMAN	ZC3H13	physical	24457600
TNR6B_HUMAN	TNRC6B	physical	24457600
GCN1_HUMAN	GCN1L1	physical	24457600
PHC3_HUMAN	PHC3	physical	24457600
DX39B_HUMAN	DDX39B	physical	24457600
FBRL_HUMAN	FBL	physical	24457600
POTEE_HUMAN	POTEE	physical	24457600
AGO2_HUMAN	AGO2	physical	24457600
DKC1_HUMAN	DKC1	physical	24457600
YTHD2_HUMAN	YTHDF2	physical	24457600
CHTOP_HUMAN	CHTOP	physical	24457600
ATX2L_HUMAN	ATXN2L	physical	24457600
PHF5A_HUMAN	PHF5A	physical	24457600
ANDR_HUMAN	AR	physical	24457600
STRBP_HUMAN	STRBP	physical	24457600
LA_HUMAN	SSB	physical	24457600
CSRP1_HUMAN	CSRP1	physical	24457600
PTBP3_HUMAN	PTBP3	physical	24457600
FXR2_HUMAN	FXR2	physical	24457600
PUM1_HUMAN	PUM1	physical	24457600
NCBP2_HUMAN	NCBP2	physical	24457600
RFOX2_HUMAN	RBFOX2	physical	24457600
ARGI1_HUMAN	ARG1	physical	24457600
SART3_HUMAN	SART3	physical	24457600
RRP5_HUMAN	PDCD11	physical	24457600
LPPRC_HUMAN	LRPPRC	physical	24457600
ZFR_HUMAN	ZFR	physical	24457600
ELAV2_HUMAN	ELAVL2	physical	24457600
CNBP_HUMAN	CNBP	physical	24457600
XRN2_HUMAN	XRN2	physical	24457600
PLRG1_HUMAN	PLRG1	physical	24457600
ZC3H4_HUMAN	ZC3H4	physical	24457600
NOL6_HUMAN	NOL6	physical	24457600
STAU1_HUMAN	STAU1	physical	24457600
UBP2L_HUMAN	UBAP2L	physical	24457600
SYNE1_HUMAN	SYNE1	physical	24457600
ENOX1_HUMAN	ENOX1	physical	24457600
CRNL1_HUMAN	CRNKL1	physical	24457600
VIR_HUMAN	KIAA1429	physical	24457600
KTN1_HUMAN	KTN1	physical	24457600
RBP2_HUMAN	RANBP2	physical	24457600
S39A7_HUMAN	SLC39A7	physical	24457600
SAP18_HUMAN	SAP18	physical	24457600
RYR3_HUMAN	RYR3	physical	24457600
REPI1_HUMAN	REPIN1	physical	24457600
CASC3_HUMAN	CASC3	physical	24457600
NUFP2_HUMAN	NUFIP2	physical	24457600
EP300_HUMAN	EP300	physical	24457600
TYY1_HUMAN	YY1	physical	24457600
HP1B3_HUMAN	HP1BP3	physical	24457600
NHP2_HUMAN	NHP2	physical	24457600
KCRU_HUMAN	CKMT1B	physical	24457600
ADNP_HUMAN	ADNP	physical	24457600
PURB_HUMAN	PURB	physical	24457600
NH2L1_HUMAN	NHP2L1	physical	24457600
CTCF_HUMAN	CTCF	physical	24457600
SRPK2_HUMAN	SRPK2	physical	24457600
CBP_HUMAN	CREBBP	physical	24457600
ZN787_HUMAN	ZNF787	physical	24457600
PAXB1_HUMAN	PAXBP1	physical	24457600
CAPZB_HUMAN	CAPZB	physical	24457600
TRI25_HUMAN	TRIM25	physical	24457600
CPEB4_HUMAN	CPEB4	physical	24457600
PURA_HUMAN	PURA	physical	24457600
SPB12_HUMAN	SERPINB12	physical	24457600
DGCR8_HUMAN	DGCR8	physical	24457600
RNPS1_HUMAN	RNPS1	physical	24457600
SCMH1_HUMAN	SCMH1	physical	24457600
STAU2_HUMAN	STAU2	physical	24457600
SUGP1_HUMAN	SUGP1	physical	24457600
PABP2_HUMAN	PABPN1	physical	24457600
PPIL1_HUMAN	PPIL1	physical	24457600
Z3H7A_HUMAN	ZC3H7A	physical	24457600
TFP11_HUMAN	TFIP11	physical	24457600
PDIA1_HUMAN	P4HB	physical	24457600
BUD31_HUMAN	BUD31	physical	24457600
ACTN1_HUMAN	ACTN1	physical	24457600
KRR1_HUMAN	KRR1	physical	24457600
PRKRA_HUMAN	PRKRA	physical	24457600
ENOX2_HUMAN	ENOX2	physical	24457600
ABC3F_HUMAN	APOBEC3F	physical	24457600
ATPB_HUMAN	ATP5B	physical	24457600
SNW1_HUMAN	SNW1	physical	24457600
MED12_HUMAN	MED12	physical	24457600
KI26B_HUMAN	KIF26B	physical	24457600
DYL1_HUMAN	DYNLL1	physical	24457600
MPP8_HUMAN	MPHOSPH8	physical	24457600
XRCC5_HUMAN	XRCC5	physical	24457600
RRP12_HUMAN	RRP12	physical	24457600
HEAT1_HUMAN	HEATR1	physical	24457600
UTP20_HUMAN	UTP20	physical	24457600
RUVB2_HUMAN	RUVBL2	physical	24457600
TGM1_HUMAN	TGM1	physical	24457600
TIA1_HUMAN	TIA1	physical	24457600
SP16H_HUMAN	SUPT16H	physical	24457600
CBX4_HUMAN	CBX4	physical	24457600
CSRP2_HUMAN	CSRP2	physical	24457600
WDR12_HUMAN	WDR12	physical	24457600
YTHD3_HUMAN	YTHDF3	physical	24457600
UBL5_HUMAN	UBL5	physical	24457600
CREST_HUMAN	SS18L1	physical	24457600
ATP5I_HUMAN	ATP5I	physical	24457600
Z385B_HUMAN	ZNF385B	physical	24457600
ZC11A_HUMAN	ZC3H11A	physical	24457600
PEO1_HUMAN	C10orf2	physical	24457600
TRAF4_HUMAN	TRAF4	physical	24457600
STRAP_HUMAN	STRAP	physical	24457600
PCNP_HUMAN	PCNP	physical	24457600
GPTC8_HUMAN	GPATCH8	physical	24457600
RED1_HUMAN	ADARB1	physical	24457600
AKAP9_HUMAN	AKAP9	physical	24457600
REQU_HUMAN	DPF2	physical	24457600
PGAM5_HUMAN	PGAM5	physical	24457600
LAS1L_HUMAN	LAS1L	physical	24457600
PDLI5_HUMAN	PDLIM5	physical	24457600
NOP14_HUMAN	NOP14	physical	24457600
M2OM_HUMAN	SLC25A11	physical	24457600
EDC4_HUMAN	EDC4	physical	24457600
GATA2_HUMAN	GATA2	physical	24457600
GEMI4_HUMAN	GEMIN4	physical	24457600
GGYF2_HUMAN	GIGYF2	physical	24457600
CSK2B_HUMAN	CSNK2B	physical	24457600
XRN1_HUMAN	XRN1	physical	24457600
TERF2_HUMAN	TERF2	physical	24457600
TF3C1_HUMAN	GTF3C1	physical	24457600
ESRP1_HUMAN	ESRP1	physical	24457600
EEA1_HUMAN	EEA1	physical	24457600
DIDO1_HUMAN	DIDO1	physical	24457600
SYAM_HUMAN	AARS2	physical	24457600
SMRC1_HUMAN	SMARCC1	physical	24457600
MRM1_HUMAN	MRM1	physical	24457600
RED_HUMAN	IK	physical	24457600
PRDX4_HUMAN	PRDX4	physical	24457600
NDKA_HUMAN	NME1	physical	24457600
NAT10_HUMAN	NAT10	physical	24457600
EFTU_HUMAN	TUFM	physical	24457600
DREB_HUMAN	DBN1	physical	24457600
AGK_HUMAN	AGK	physical	24457600
TCPG_HUMAN	CCT3	physical	24457600
SFXN1_HUMAN	SFXN1	physical	24457600
SC31B_HUMAN	SEC31B	physical	24457600
PHF6_HUMAN	PHF6	physical	24457600
PPIE_HUMAN	PPIE	physical	24457600
PTCD3_HUMAN	PTCD3	physical	24457600
NDUA4_HUMAN	NDUFA4	physical	24457600
DIC_HUMAN	SLC25A10	physical	24457600
FXR1_HUMAN	FXR1	physical	24457600
CELF1_HUMAN	CELF1	physical	24457600
SMCA5_HUMAN	SMARCA5	physical	24457600
AGO1_HUMAN	AGO1	physical	24457600
NKRF_HUMAN	NKRF	physical	24457600
CSTF1_HUMAN	CSTF1	physical	24457600
CHD3_HUMAN	CHD3	physical	24457600
ACL6A_HUMAN	ACTL6A	physical	24457600
ZN687_HUMAN	ZNF687	physical	24457600
WBP11_HUMAN	WBP11	physical	24457600
WDR5_HUMAN	WDR5	physical	24457600
SSRD_HUMAN	SSR4	physical	24457600
GEMI2_HUMAN	GEMIN2	physical	24457600
SRP14_HUMAN	SRP14	physical	24457600
RSRC1_HUMAN	RSRC1	physical	24457600
AT2A3_HUMAN	ATP2A3	physical	24457600
P5CR1_HUMAN	PYCR1	physical	24457600
NOL9_HUMAN	NOL9	physical	24457600
MRT4_HUMAN	MRTO4	physical	24457600
MIC60_HUMAN	IMMT	physical	24457600
TIM50_HUMAN	TIMM50	physical	24457600
EHMT1_HUMAN	EHMT1	physical	24457600
FA98B_HUMAN	FAM98B	physical	24457600
RPN1_HUMAN	RPN1	physical	24457600
DI3L2_HUMAN	DIS3L2	physical	24457600
SERA_HUMAN	PHGDH	physical	24457600
BIG3_HUMAN	KIAA1244	physical	24457600
SYYM_HUMAN	YARS2	physical	24457600
RBM14_HUMAN	RBM14	physical	24457600
HACD3_HUMAN	PTPLAD1	physical	24457600
TM41B_HUMAN	TMEM41B	physical	24457600
NFX1_HUMAN	NFX1	physical	24457600
CFA20_HUMAN	CFAP20	physical	24457600
PSB5_HUMAN	PSMB5	physical	24457600
PKP2_HUMAN	PKP2	physical	24457600
PPIB_HUMAN	PPIB	physical	24457600
NDKM_HUMAN	NME4	physical	24457600
NXF1_HUMAN	NXF1	physical	24457600
LC7L3_HUMAN	LUC7L3	physical	24457600
LENG8_HUMAN	LENG8	physical	24457600
CBX2_HUMAN	CBX2	physical	24457600
CTND1_HUMAN	CTNND1	physical	24457600
ABCB6_HUMAN	ABCB6	physical	24457600
AIFM1_HUMAN	AIFM1	physical	24457600
MEPCE_HUMAN	MEPCE	physical	24457600
ZN740_HUMAN	ZNF740	physical	24457600
ZCHC3_HUMAN	ZCCHC3	physical	24457600
SMRD2_HUMAN	SMARCD2	physical	24457600
SRP09_HUMAN	SRP9	physical	24457600
RCN1_HUMAN	RCN1	physical	24457600
NOP10_HUMAN	NOP10	physical	24457600
DUS14_HUMAN	DUSP14	physical	24457600
CLN6_HUMAN	CLN6	physical	24457600
CALX_HUMAN	CANX	physical	24457600
RLA1_HUMAN	RPLP1	physical	24457600
ZCCHL_HUMAN	ZC3HAV1L	physical	24457600
YAF2_HUMAN	YAF2	physical	24457600
DUS11_HUMAN	DUSP11	physical	24457600
RYBP_HUMAN	RYBP	physical	24457600
MBNL2_HUMAN	MBNL2	physical	24457600
INT6_HUMAN	INTS6	physical	24457600
H1X_HUMAN	H1FX	physical	24457600
DPM1_HUMAN	DPM1	physical	24457600
BMI1_HUMAN	BMI1	physical	19956605
ENL_HUMAN	MLLT1	physical	25921070
UBP7_HUMAN	USP7	physical	25605328
SCML2_HUMAN	SCML2	physical	25605328
NBN_HUMAN	NBN	physical	25088203
RING2_HUMAN	RNF2	physical	25843776
RING2_HUMAN	RNF2	physical	26151332
BMI1_HUMAN	BMI1	physical	26151332
UB2D3_HUMAN	UBE2D3	physical	26151332
H1X_HUMAN	H1FX	physical	26468281
CBX5_HUMAN	CBX5	physical	26468281
LMNA_HUMAN	LMNA	physical	26468281
LMNB2_HUMAN	LMNB2	physical	26468281
DEK_HUMAN	DEK	physical	26468281
BAF_HUMAN	BANF1	physical	26468281
BAZ1A_HUMAN	BAZ1A	physical	26468281
CENPV_HUMAN	CENPV	physical	26468281
NUP93_HUMAN	NUP93	physical	26468281
IMB1_HUMAN	KPNB1	physical	26468281
IMA1_HUMAN	KPNA2	physical	26468281
HDAC2_HUMAN	HDAC2	physical	26468281
BAZ1B_HUMAN	BAZ1B	physical	26468281
RING2_HUMAN	RNF2	physical	26468281
ATRX_HUMAN	ATRX	physical	26468281
CDKN3_HUMAN	CDKN3	physical	26468281
H31_HUMAN	HIST1H3A	physical	26468281
H11_HUMAN	HIST1H1A	physical	26468281
MUC1_HUMAN	MUC1	physical	27893710
PHC2_HUMAN	PHC2	physical	27827373
BMI1_HUMAN	BMI1	physical	27827373
UBR5_HUMAN	UBR5	physical	27647897
UBP2L_HUMAN	UBAP2L	physical	27647897
RING2_HUMAN	RNF2	physical	27647897
CBX3_HUMAN	CBX3	physical	27647897
CBX4_HUMAN	CBX4	physical	27647897
PHC1_HUMAN	PHC1	physical	27647897
HNF4A_HUMAN	HNF4A	physical	25391650

Drug and Disease Associations

Kegg Disease
There are no disease associations of PTM sites.
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of BMI1_HUMAN

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Global, in vivo, and site-specific phosphorylation dynamics insignaling networks."; Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P.,Mann M.; Cell 127:635-648(2006). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-251; SER-253 ANDSER-255, AND MASS SPECTROMETRY.	17081983 [Abstract]